Results 1 to 10 of about 1,868 (100)

环状RNA circ_0120051通过miR-144-3p/IDH2轴抑制心肌成纤维细胞的纤维化表型研究

Zhongshan Daxue xuebao. Yixue kexue ban
目的研究环形 RNA circ_0120051对心肌成纤维细胞的纤维化表型的调控作用和机制。方法通过实时萤光定量PCR（RT-qPCR）检测健康器官捐献者（n=24）与心力衰竭（HF）病人（n=21）心肌标本中 circ_0120051及其宿主基因溶质载体家族8成员A1（SLC8A1）的表达水平。核糖核酸外切酶（RNase R）消化实验鉴定circ_0120051的RNA稳定性。RT-qPCR检测circ_0120051在人心肌细胞AC16中的核质分布情况。利用腺病毒在C57BL/6乳小鼠心肌成纤维细胞（
梁俣, 胡志琴, 温艺红, 伍华燕, 王娅, 刘宇鹏, 单志新, 方咸宏   +7 more
doaj  

[Advances in ribosome biogenesis and targeted therapies for diffuse large B-cell lymphomas]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Yue MX, Zhao WL, Wang L.
europepmc   +1 more source

狭缝引导配体1-3’非翻译区抑制心肌成纤维细胞纤维化表型的作用

Zhongshan Daxue xuebao. Yixue kexue ban
目的研究狭缝引导配体1（Slit1）的3’非翻译区序列部分片段（Slit1-3’UTR）对心肌成纤维细胞的纤维化表型的调节作用和可能机制。方法利用腺病毒介导在ICR乳小鼠心肌成纤维细胞（mCFs）中过表达Slit1-3’UTR 1526nt序列（Slit1-3’UTR 1526nt），使用蛋白质免疫印迹技术评估mCFs中胶原Iα1/（COL1A1）、胶原IIIα1/（COL3A1）、α平滑肌肌动蛋白（α-SMA）等纤维化相关基因的表达水平，结合EdU和Trans ...
王娅, 伍华燕, 高原, 吴茹诗, 关佩莹, 李晖, 方俊涛, 单志新   +7 more
doaj  

[Liraglutide improves cardiac structure and function in mice with advanced diabetic nephropathy and massive proteinuria]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yan Y, Yang W, Li W, Yang C, Wang F, Wang J.   +5 more
europepmc   +1 more source

[Progress in clinical research related to viral hepatitis in 2025]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ding Y, Li Y, Dou XG.
europepmc   +1 more source

[Ultrafine <i>Xiebai</i> powder alleviates lipopolysaccharide-induced acute lung injury in mice by suppressing ferroptosis and modulating the NF-κB/STAT3 signaling axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhu J, Shao N, Huang Z, Liu Y, Meng X, Liu Z, Sun Y, Dong J, Fan H.   +8 more
europepmc   +1 more source

[Modified <i>Gandou</i> Decoction improves cognitive function of TX mice with Wilson's disease by inhibiting the PKR/eIF2α pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xu C, Han Y, Cheng N, Dong J.
europepmc   +1 more source

[Single-cell RNA sequencing of B cells reveals molecular typing in Sjögren syndrome]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Lin W, Xie Y, Wang F, Wang S, Liu X, Hu F, Jia Y.   +6 more
europepmc   +1 more source

[Progress in regulating stem cell functions for repair and regeneration of craniomaxillofacial tissues]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Zhang H, Yang F, Yang R.
europepmc   +1 more source

[Study on the role and mechanism of quercetin promoting autophagy in HCCLM3 cells via STING signaling]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Chen L, Wu GZ, Zhu Y, Zhang TT.
europepmc   +1 more source