On the low reproducibility of cancer studies.
National Science Review, 2018 早前有研究指出，近九成肿瘤生物学论文的实验结果不能重复。最近，eLife期刊上刊登了五个详细的重复性研究，将这一数字证实。研究结果的不可重复常被归咎于人为因素，因而认为可以避免。但是其原因也可能是生物学上的，以致这些研究本质上就无法重复。肿瘤研究的可重复率低，将深刻地影响到临床的方案，同时也反映出肿瘤生成多样的进化通路。 背 景 可重复性是实验科学的基础。尽管多种因素困扰着不同研究领域，影响的程度也不尽相同，肿瘤研究却显得首当其冲。早前一个报告指出，53个发表的肿瘤研究，只有6个的结论可被重复 ...
Haijun Wen +3 more
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Tracing natural groundwater recharge to the Thiaroye aquifer of Dakar, Senegal
Hydrogeology Journal, 2019 Urban groundwater in Sub-Saharan Africa provides vital freshwater to rapidly growing cities. In the Thiaroye aquifer of Dakar (Senegal), groundwater within Quaternary unconsolidated sands provided nearly half of the city’s water supply into the 1980s ...
S. C. Faye +7 more
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4.2—90K固体比热容国家标准的建立——I.25—90K自动绝热量热计及α-Al 2 O 3 的摩尔热容
, 1990 本文详细描述了一套用于25—90K温区内精密测定固体热容的自动绝热量热计及其低温恒温器的结构,对样品容器特别设计了与内壁非接触、薄壁径向、分布均匀的散热片,充分改善了量热容器内部的热平衡条件,对绝热控制研制了专用的高精度ACD-79型绝热控温仪,大大提高了量热系统中热屏和导线的控温精度,用国产标准参考材料,高纯α-A1 2 O 3 检测了该量热计的性能;α-A1 2 O 3 摩尔热容实验结果与美国标准局数据比对其标准偏差为±0.3％—±0.1％。
谭志诚 +7 more
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室温离子液体[bmim][BF4]和水混合物的计算机模拟研究
, 2005 针对室温离子液体[bmim][BF4]和水的混合物,用分子动力学模拟研究了溶液的微观组成与浓度的关系.模拟结果表明:该混合物中各组分间的径向分布函数随[bmim][BF4]摩尔分数的增加呈有规律的变化;在此基础上计算了溶液的局部组成以及组分间的缔合因子,进一步考察了各组分间的相互作用情况;另外基于Kirkwood-Buff理论估算了混合物的偏摩尔体积、等温压缩因子以及活度系数对浓度的偏导数,对于理解离子液体与水之间的交互作用具有一定的参考意义.
吴晓萍, 刘志平
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[A comparative study of different methods for treatment switching analysis in clinical trials]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLiang Z, Xu L, Li K, Yu M, An S.
europepmc +1 more source
[Parameter estimation using time-dependent Weibull proportional hazards model for survival analysis with partly interval censored data]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoWang S, Liu X, Li R, Li Y.
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[Development and evaluation of a positioning system for radiotherapy patient based on structured light surface imaging]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiWang Y +6 more
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[Meta analysis of the prevalence and risk factors of non-alcoholic fatty liver disease in overweight and obese children and adolescents in China]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiXiao Y +5 more
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[Poster Fusion Cage combined with xenogeneic bone graft augmentation for bone defect management in distal radius fractures]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiGao Y +6 more
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[Application of electrical impedance tomography in diagnosis and monitoring of pulmonary diseases]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiHu X +6 more
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