[Efficacy of Ganciclovir Combined With Recombinant Human Interferon α-1b for Viral Encephalitis in Children]. [PDF]
Han B, Zhao L, Han X, Kong N, Qin X.
europepmc +1 more source
用紫外线灭活的草鱼呼肠孤病毒 (GCRV)诱导鲫鱼囊胚细胞 (CAB)能产生一种高滴度的抗病毒物质。这种物质在 5 6℃及 pH 2~ 11稳定 ;对胰蛋白酶敏感 ;抗病毒活性受被保护细胞的密度、培养温度及保护时间的影响 ;不能被GCRV的特异性抗体中和 ;无直接杀病毒作用 ;抗病毒机制依赖于细胞内RNA和蛋白质的合成 ;在多种鱼类培养细胞中具有抑制病毒作用。这些特性与哺乳类α/ β干扰素一致 ...
张义兵,王铁辉,李戈强,贾方钧,俞小牧
core
[High expression of low-risk hpv in nasal inverted papilloma and its response to interferon therapy]. [PDF]
He Z, Lyu S, Huang M, Li X.
europepmc +1 more source
[Expert recommendations on the management of adverse reactions in pegylated interferon alpha therapy for chronic hepatitis B]. [PDF]
Expert Group on the Management of Adverse Reactions in Pegylated Interferon Alpha Therapy for Chronic Hepatitis B.
europepmc +1 more source
目的:考察不同添加剂对重组人α干扰素稳定性的影响。方法:取无菌过滤的重组干扰素纯品,分别加入不同浓度和种类的添加剂,37℃存放30 d后通过高效凝胶过滤色谱监测溶液中单体、二聚体及可溶寡聚体的含量变化,同时通过抗病毒能力考察存放过程中的生物活性变化情况。结果:pH 7.0时干扰素稳定性最强,碱性条件下加剧寡聚体形成。存放过程中添加海藻糖或甘露醇以及低浓度的聚山梨酯(<0.01%)可提高其储存稳定性。结论 ...
陈文琼, 刘永东
core
[Study on the role and mechanism of quercetin promoting autophagy in HCCLM3 cells via STING signaling]. [PDF]
Chen L, Wu GZ, Zhu Y, Zhang TT.
europepmc +1 more source
古尔班通古特沙漠作为北疆冬季牧场,普遍承受牲畜的践踏干扰,研究表明:动物践踏干扰导致各种类型生物结皮的覆盖度有不同程度的降低,干扰主要集中于结皮层(0~2 cm)。微生物各类群对践踏干扰的反应具差异性,真菌与干扰的相关性最高,细菌和放线菌对干扰不敏感。践踏干扰改变了微生物各类群在垄间低地的数量垂直分布格局,但并未改变微生物区系组成。有机质对干扰不敏感,仍随土层加深而递减,在结皮层(0~2 cm ...
梁少民 +4 more
core
[Comparison of antiviral efficacy of nucleos(t)ide analogue monotherapy and its combination with interferon-α in children 1-6 years-old with HBeAg-positive chronic hepatitis B]. [PDF]
Wang ZW +11 more
europepmc +1 more source
[A case of hepatitis B surface antigen clearance achievement based on the combination of interferon and intermittent consolidation therapy]. [PDF]
Deng W +5 more
europepmc +1 more source

