Results 31 to 40 of about 31,792 (238)

The expression and clinical significance of SATB2 in Esophageal Squamous Cell Carcinoma [PDF]

open access: yes, 2015
摘要 研究目的:食管癌在中国是一种高发的消化系统恶性肿瘤。由于解剖位置深、临床症状隐匿、早期症状不明显、易以多种路径转移、高位癌手术残留、术后容易复发以及放化疗不敏感等特点,食管癌预后较差。因此,进一步深入研究食管癌发生发展、侵袭转移以及预后评估因素的内在机制具有重要的意义。SATB1是富含AT序列结合蛋白的特殊家庭成员之一,已被证明影响众多肿瘤致瘤性的过程。SATB2与肿瘤的关系密切一直是研究的关注点,然而,其在食管鳞状细胞癌组织中的作用不清楚。本论文以食管鳞癌为研究对象,以SATB2为切入点 ...
李宁
core  

Emotion and the Advocacy Coalition Framework: An Affective Dynamics Perspective

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT Despite extensive evidence that emotion and cognition are deeply intertwined, the Advocacy Coalition Framework (ACF) lacks an analytically independent emotional mechanism in its causal architecture—an omission that may be particularly consequential in policy subsystems structured around morally charged, identity‐laden policy disputes.
Moshe Maor
wiley   +1 more source

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

open access: yesVeterinary Dermatology, EarlyView.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake   +2 more
wiley   +1 more source

Immunorecognition of Estrogen Receptor in the Optic Ganglion of Scylla serrata [PDF]

open access: yes, 2006
【中文摘要】 利用免疫细胞化学SABC法对锯缘青蟹(Scylla serrata)视神经节雌激素受体(ER)进行定位研究.结果表明:视神经节的视外髓、视内髓和视端髓存在ER免疫阳性细胞.视神经节存在的ER免疫阳性细胞可以为雌激素提供结合位点.本研究为雌激素参与视神经节神经内分泌调节作用提供了形态学依据.
叶海辉   +5 more
core  

数学形态学在串联型故障电弧诊断中的应用

open access: yesGaoya dianqi, 2016
故障电弧是导致设备或线路电气火灾故障的原因之一。为了实现对配电系统中串联型故障电弧的快速诊断,文中提出了一种基于数学形态学的串联型故障电弧诊断方法。该方法利用数学形态学的开闭运算,有效地滤除电流信号中的噪声干扰,并通过多分辨率形态梯度(MMG)运算提取串联型故障电弧发生前后电流波形的突变特征,进而获取正常工作情况下和故障电弧发生时线路电流波形的形态梯度值。通过比较故障发生前后线路电流波形形态梯度值的大小,可以准确地判断出线路是否发生了电弧故障。该串联故障电弧诊断方法具有逻辑运算简单 ...
刘振国, 孙鹏, 由广祥
doaj  

车轮虫分类与系统发育研究进展 [PDF]

open access: yes, 2007
车轮虫属一大类寄生性纤毛虫原生动物,可不同程度地给宿主造成危害,故对其研究既具有理论意义,又具有经济价值。文中简单回顾了车轮虫的分类研究和系统发育研究的历史。在分类学研究领域方面,全面介绍了目前车轮虫科已发现属的寄生部位和地理分布等;而系统发育研究领域方面,则介绍了车轮虫研究在萌芽期、探索期和发展期这三个时期的进展,包括形态学和分子生物学两方面的研究内容 ...
余育和, 龚迎春
core  

Effect of Worm‐Like Amorphous Phase on Corrosion Resistance and Antibacterial Properties of NiTiCu Alloy

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT By adding CuO, the worm‐like amorphous phase and atomic clusters were simultaneously introduced, enabling the (Ni40Ti40Cu20)99.9O0.1 alloy micron columns to exhibit a uniform flow strain of over 40% and a strength of over 2.5 GPa during compression.
Huwen Ma   +13 more
wiley   +1 more source

Genomic responses to increased temperature and pollinator selection in Brassica rapa L.

open access: yesNew Phytologist, Volume 250, Issue 2, Page 1231-1247, April 2026.
Summary Rapid environmental change reshapes both abiotic stress and biotic interactions, yet it remains unclear how these combined forces structure plants' genomic adaptation. In particular, the joint influence of temperature and pollinator identity, two ecological axes undergoing simultaneous global shifts, has rarely been quantified at genomic ...
Yanqian Ding, Florian P. Schiestl
wiley   +1 more source

Study on the species identification and the species interactions in the phycosphere of Alexandrium tamarense [PDF]

open access: yes, 2015
本文发现了一种生活在塔玛亚历山大藻(Alexandriumtamarense)藻际中的棕鞭藻。通过形态学和分子生物学的综合分析,确定该棕鞭藻为棕鞭藻(Ochromonassp.)。应用传统生物学与现代微流控技术相结合的手段,研究了该棕鞭藻的生活习性,并对藻际中塔玛亚历山大藻、棕鞭藻、细菌三者之间的相互关系进行了研究。本文的研究内容主要有一下几个方面: 1.通过光学显微镜、荧光显微镜和扫描电子显微镜对该棕鞭藻进行了形态学观察,确定了棕鞭藻的大小为2-3μm,外表呈球形,头部端具不等长的两条鞭毛 ...
胡丽丹
core  

Development of Radiolabeled tumor-specific targeting peptides for PET Imaging [PDF]

open access: yes, 2015
多肽具有优良的药动学特性和生物学活性,因此在PET分子影像领域,多肽类分子影像探针展现出广阔的应用前景和优势。本课题利用AlF螯合法标记多肽,开发出一系列PET探针,并对相应探针进行体外及体内生物学评价。本课题具体研究内容可分为四部分。 第一部分,肝癌是最常见也是最致命的癌症之一,对于肝癌转移复发目前尚无行之有效的诊断、治疗方法。本研究通过固相法合成NOTA-G-TMTP1,并利用18F标记制得PET探针[18F]AlF-NOTA-G-TMTP1。[18F]AlF-NOTA-G-TMTP1标记产率为 ...
李业森
core  

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