, 2016 接种疫苗是预防H5N1禽流感爆发的有效手段，H5N1流感疫苗免疫原性较差，抗原用量高，需要添加佐剂以提高疫苗效果。壳聚糖微球作为颗粒型佐剂具有良好的生物相容性和免疫刺激性。然而，壳聚糖微球的制备及其作为疫苗佐剂的应用还存在以下的需求与问题：1）传统的壳聚糖微球制备方法（如机械搅拌法、凝聚法等）所制备的微球粒径不均一，产品的稳定性与重复性差；2）与包埋相比，抗原吸附过程简单，在细胞内易于释放抗原，而高抗原吸附率要求制备阳离子性、网络多孔的壳聚糖微球，以增大抗原与微球的接触面积与结合力；3 ...
王月琦
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[Research progress in diagnosis and treatment of non-tumorous salivary gland diseases]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanCong X, Su J, Wu L, Ding C, Li W, Yu G.
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Effect of inward rectifier potassium 2.1 channel on the osteogenic differentiation of human dental follicle cells and its mechanism. [PDF]
Hua Xi Kou Qiang Yi Xue Za Zhi, 2022 Zhang P +5 more
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Effect of CaCl_2 on Fine Sediment Flocculation and Settling in Still Water
, 2000 细颗粒泥沙的絮凝或分散对土壤渗透性、土壤可蚀性有重要作用 ,是水土保持研究的重要内容。在 Ca Cl2 浓度为 0～ 1.0 mmol/L ,泥沙浓度为 10 g/L时 ,用吸管法研究了 Ca Cl2 对细颗粒泥沙絮凝沉降的影响。结果表明 :泥沙沉降分 2个阶段 ,分选沉降段和絮凝沉降段 ;在絮凝沉降段 ,Ca Cl2 浓度越大 ,絮凝沉降越快。但较高浓度时 ,细颗粒泥沙平均沉速反而随 Ca Cl2浓度增大而逐渐减小 ;泥沙浓度随时间呈指数衰减 ;细颗粒泥沙絮凝临界粒径为 0 .0 ...
邵明安, 陈洪松
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Numerical study of flocculation settling of cohesive sediment
, 2010 盐度等因素对泥沙絮凝沉降的影响是本文的研究目的.考虑了泥沙颗粒在水中的多体相互作用, 以及颗粒间的XDLVO势.分析了盐度、泥沙浓度、Hamaker常数、水合作用对泥沙絮凝沉降的影响.获得的泥沙絮凝沉降速度的拟合公式与计算和试验相符 ...
王龙, 李家春, 周济福
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[In vivo experimental study of acute intraocular hypertension in rabbit based on particle image velocimetry technique]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2020 Li Q, Wang W, Long X, Yang H, Song H.
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[Succinate Dehydrogenase-Deficient Renal Cell Carcinoma: Clinicopathological Analysis of 11 Cases]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanPan X +7 more
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[High-mobility group protein 1 promotes diethylnitrosamine-induced liver cancer formation in mice by activating mitochondrial biogenesis]. [PDF]
Zhonghua Gan Zang Bing Za Zhi, 2020 He XB +5 more
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[Use of Trichosanthis fructus and the core drug pair Trichosanthis fructus-Glycyrrhizae radix et rhizoma in traditional Chinese prescriptions: molecular mechanisms in network pharmacology and molecular docking]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2021 Yan H, Zou C.
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