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不同剂量血管紧张素-（1-7）对心力衰竭大鼠心室有效不应期及心室颤动阈值的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】观察不同剂量血管紧张素-（1-7）对慢性心力衰竭大鼠心室有效不应期及心室颤动阈值的影响。【方法】40只Wistar大鼠成功建立慢性心力衰竭模型，随机分为心力衰竭组（n=10）、心力衰竭并血管紧张素-（1-7）处理3个剂量组（每组n=10）。另取10只Wistar大鼠行假手术，为正常对照组。用心电生理研究方法测定心室有效不应期（VERP）、心室颤动阈值（VFT）的变化，比较心力衰竭并血管紧张素-（1-7）处理的3个剂量组、心力衰竭组及正常对照组各项指标。【结果】心力衰竭大鼠VERP（73．5ms ...
方昶 +4 more
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肾素-血管紧张素系统基因多态性与慢性心力衰竭的关系 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]探讨中国南方汉族人群中,血管紧张素转换酶（ACE）及血管紧张素原（AGT）双基因多态性与慢性心力衰竭发病的关系.[方法]用聚合酶链反应及限制性片段长度多态性技术检测111例慢性心力衰竭患者和110例健康者的ACE基因I/D及AGT基因M235T的多态性.[结果]①慢性心力衰竭组DD基因型与D等位基因的频率均高于对照组.DD基因型0.468比0.227,P＜0.01;D等位基因0.667比0.436,P＜0.01.②AGT基因M235T多态性在慢性心力衰竭组及对照组的分布无统计学差异 ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 2004 【目的】 探讨慢性心力衰竭患者血清瘦素水平改变及其与胰岛素抵抗?胰岛素水平之间的关系? 【方法】 观察60例慢性心力衰竭患者及30例正常对照组血清瘦素水平变化,分析血清瘦素与胰岛素抵抗(以I-AI表示)?胰岛素水平之间的关系? 【结果】 慢性心力衰竭组血清瘦素水平较正常对照组明显升高(12.0±3.4)ng/mL vs (6.3±2.0) ng/mL, P < 0.01?与对照组相比,慢性心力衰竭组胰岛素浓度升高(24.1±5.5) ×10-3 U/L vs (13.9±3.1) ×10-3U/L, P
冷秀玉
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Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨心力衰竭患者心率变异能谱及其昼夜规律的变化以及相关的病理生理基础。【方法】对45 例充血 性心力衰竭连续病例(分为NYHA 心功能≥ Ⅲ 级组和心功能Ⅱ 级组两组)与30 例心功能正常组对照研究。采用Holter 24 h 全信息心电记录, 计算机分析系统对心率变异能谱进行分析。同时用放射免疫法测定各组患者血浆肾素活性及血管紧张素 Ⅱ 、醛固酮血浆浓度。【结果】①随着心力衰竭加重, 心率变异低能谱范围逐渐下降;Ⅱ 级心功能组高能谱范围突然下降, 与正 常心功能组对比差异有显著性(P ...
高修仁 +6 more
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Efficacy and Safety Combined with Conventional and Western Medicine Treatments on Coronary Heart Disease Complicated with Heart Failure：a Systematic Review [PDF]
, 2022 BackgroundAnti-atherosclerotic and anti-heart failure therapies are the key to the treatment of coronary heart disease (CHD) , a common cardiovascular disease.
WANG Tianyuan, WANG Yanbo, FENG Shuo, HU Jing, ZHANG Huina, WANG Hong, LI Bo
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Reliability and Validity of the Chinese Version of the Partners in Health Scale in Patients with Chronic Heart Failure [PDF]
, 2022 BackgroundChronic heart failure (CHF) is a common cardiovascular disease. Improving the self-management ability of CHF patients will contribute to quality of life improvement and reduction of rehospitalization and mortality rates. The Partners in Health (
WANG Xiaonan, JIANG Ying, KANG Xiaofeng, JI Shiming, ZHANG Jian
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Heart Failure with Mid-range Ejection Fraction——a Comprehension of the Disease [PDF]
, 2022 Heart failure is the final main battlefield of various cardiovascular diseases with huge harm, which can cause all kinds of arrhythmias and even sudden cardiac death. The 2016 ESC guidelines formally define heart failure with mid-range ejection fraction (
RUAN Zheng, HUANG Jianyu, JIANG Wencai, CHEN Meixiang, QIN Changyu, XU Lin
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Characteristics and Prognosis of Herat Failure with Improved Ejection Fraction [PDF]
, 2022 BackgroundLeft ventricular ejection fraction (LVEF) is often used to classify heart failure (HF) . Some HF patients were observed to have improved ejection fraction after treatment, thus giving rise to the concept of HF with improved EF (HFimpEF ...
SU Kangkang, WANG Yan, WANG Lili, CHEN Shuxia, GU Jian
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, 2021 目的探讨外周血白细胞端粒长度与慢性心力衰竭（CHF）发生风险的相关性。方法本研究招募了224例患者，根据左心室射血分数分为非CHF（Non-CHF）组（117例）和CHF组（107例），用实时荧光定量多聚核苷酸链式反应（ qPCR） 进行外周血白细胞端粒长度的测量。比较Non-CHF组和CHF组患者端粒长度，并采用二元 Logistic回归模型分析端粒长度与CHF发生风险是否相关。结果Non-CHF组和CHF组患者外周血白细胞端粒相对长度分别为0.9（0.64~1.18）、0.7（0.53~0.89 ...
吴智业 +5 more
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Interpretation of the 2015 guidelines on diagnosis and treatment of endogenous subclinical hyperthyroidism by the European Thyroid Association [PDF]
, 2017 亚临床甲状腺功能亢进症在临床中很常见,但对其危害及处理有很大的争议。欧洲甲状腺学会根据现有的临床证据,公布了内因性亚临床甲状腺功能亢进症诊治指南; 。指南强调,要确立持续性亚临床甲状腺功能亢进症的诊断,明确其病因,按照其进展为临床甲亢、发生不良心血管事件及骨质疏松风险进行危险分层,以指导临床; 处理。Endogenous subclinical hyperthyroidism (Endo SHyper) is a common form of; thyroid diseases.
刘超, 李学军, 肖方森
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