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不同剂量血管紧张素-(1-7)对心力衰竭大鼠心室有效不应期及心室颤动阈值的影响 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2006
【目的】观察不同剂量血管紧张素-(1-7)对慢性心力衰竭大鼠心室有效不应期及心室颤动阈值的影响。【方法】40只Wistar大鼠成功建立慢性心力衰竭模型,随机分为心力衰竭组(n=10)、心力衰竭并血管紧张素-(1-7)处理3个剂量组(每组n=10)。另取10只Wistar大鼠行假手术,为正常对照组。用心电生理研究方法测定心室有效不应期(VERP)、心室颤动阈值(VFT)的变化,比较心力衰竭并血管紧张素-(1-7)处理的3个剂量组、心力衰竭组及正常对照组各项指标。【结果】心力衰竭大鼠VERP(73.5ms ...
方昶   +4 more
doaj   +2 more sources

肾素-血管紧张素系统基因多态性与慢性心力衰竭的关系 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2006
[目的]探讨中国南方汉族人群中,血管紧张素转换酶(ACE)及血管紧张素原(AGT)双基因多态性与慢性心力衰竭发病的关系.[方法]用聚合酶链反应及限制性片段长度多态性技术检测111例慢性心力衰竭患者和110例健康者的ACE基因I/D及AGT基因M235T的多态性.[结果]①慢性心力衰竭组DD基因型与D等位基因的频率均高于对照组.DD基因型0.468比0.227,P<0.01;D等位基因0.667比0.436,P<0.01.②AGT基因M235T多态性在慢性心力衰竭组及对照组的分布无统计学差异 ...
doaj   +2 more sources

慢性心力衰竭血清瘦素及其与胰岛素抵抗的关系 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2004
【目的】 探讨慢性心力衰竭患者血清瘦素水平改变及其与胰岛素抵抗?胰岛素水平之间的关系? 【方法】 观察60例慢性心力衰竭患者及30例正常对照组血清瘦素水平变化,分析血清瘦素与胰岛素抵抗(以I-AI表示)?胰岛素水平之间的关系? 【结果】 慢性心力衰竭组血清瘦素水平较正常对照组明显升高(12.0±3.4)ng/mL vs (6.3±2.0) ng/mL, P < 0.01?与对照组相比,慢性心力衰竭组胰岛素浓度升高(24.1±5.5) ×10-3 U/L vs (13.9±3.1) ×10-3U/L, P
冷秀玉
doaj   +2 more sources

心力衰竭心率变异能谱及其昼夜规律变化 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2002
【目的】探讨心力衰竭患者心率变异能谱及其昼夜规律的变化以及相关的病理生理基础。【方法】对45 例充血 性心力衰竭连续病例(分为NYHA 心功能≥ Ⅲ 级组和心功能Ⅱ 级组两组)与30 例心功能正常组对照研究。采用Holter 24 h 全信息心电记录, 计算机分析系统对心率变异能谱进行分析。同时用放射免疫法测定各组患者血浆肾素活性及血管紧张素 Ⅱ 、醛固酮血浆浓度。【结果】①随着心力衰竭加重, 心率变异低能谱范围逐渐下降;Ⅱ 级心功能组高能谱范围突然下降, 与正 常心功能组对比差异有显著性(P ...
高修仁   +6 more
doaj   +2 more sources

Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study 糖尿病血压控制目标(BPROAD)研究的原理和设计

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1029-1040, December 2023., 2023
Highlights The Blood Pressure Control Target in Diabetes (BPROAD) study is a multicenter, randomized controlled trial conducted in mainland China to test the hypothesis of whether intensive blood pressure (BP) management (systolic BP <120 mm Hg) has additional benefits over standard BP management (systolic BP <140 mm Hg) over a follow‐up period of up ...
The BPROAD Study Group   +18 more
wiley   +1 more source

A network meta‐analysis of association between cardiometabolic risk factors and COVID‐19 outcome severity 心血管代谢危险因素与COVID‐19严重程度关联的网络荟萃分析

open access: yesJournal of Diabetes, Volume 15, Issue 11, Page 968-977, November 2023., 2023
Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li   +9 more
wiley   +1 more source

Developing a prediction model for all‐cause mortality risk among patients with type 2 diabetes mellitus in Shanghai, China 中国上海地区建立的2型糖尿病患者全因死亡风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 1, Page 27-35, January 2023., 2023
Highlights This study constructed the first 5‐year all‐cause mortality risk prediction model for patients with type 2 diabetes mellitus in south China. This well‐performing model, using highly accessible predictors collected in routine clinical settings, provides a powerful tool for clinicians to identify high‐risk diabetic patients.
Jiying Qi   +10 more
wiley   +1 more source

Implications of fetal premature atrial contractions: systematic review

open access: yesUltrasound in Obstetrics &Gynecology, Volume 60, Issue 6, Page 721-730, December 2022., 2022
ABSTRACT Objective Fetal heart‐rate irregularities occur in 1–2% of pregnancies and are usually caused by premature atrial contractions (PAC). Although PAC are considered benign, they may be associated with cardiac defects and tachyarrhythmia. We aimed to determine the incidence of congenital heart defects (CHDs) and complications in fetuses with PAC ...
B. B. Bet   +6 more
wiley   +1 more source

Health utilities in Chinese patients with coronary heart disease and impaired glucose tolerance (ACE): A longitudinal analysis of a randomized, double‐blind, placebo‐controlled trial 中国冠心病合并糖耐量异常患者的健康相关生活质量:一项随机、双盲、安慰剂对照试验的纵向分析

open access: yesJournal of Diabetes, Volume 14, Issue 7, Page 455-464, July 2022., 2022
Highlights The Acarbose Cardiovascular Evaluation (ACE) trial assessed the effects of acarbose in patients with coronary heart disease (CHD) and impaired glucose tolerance (IGT) in China. Acarbose treatment did not impact on health‐related quality of life in ACE trial participants with CHD and IGT. Myocardial infarction (MI), stroke, heart failure, and
José Leal   +4 more
wiley   +1 more source

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