急性冠脉综合征患者负荷量阿托伐他汀对择期经皮冠脉 介入术诱导的炎症反应与心肌损伤的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 探讨我国急性冠脉综合征患者择期冠脉介入术(PCI)术前给予负荷量阿托伐他汀对术后炎症因子与心肌损伤标志物的影响65377;【方法】 入选2008年11月至2009年7月在我院行择期冠脉介入术的急性冠脉综合征连续病例85例,随机分为实验组和对照组,分别为42例和43例65377;实验组在阿托伐他汀20 mg/d基础上,术前8 h再给予负荷量阿托伐他汀80 mg,对照组仅给予阿托伐他汀20 mg/d65377;分别在术前65380;术后6 h及术后24 h检测炎症因子单核细胞趋化因子-1(MCP ...
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Effect of ApoB/ApoA1 ratio on the all-cause mortality of patients with pulmonary embolism [PDF]
, 2023 Objective To investigate the effect of ApoB/ApoA1 ratio on the all-cause mortality of patients with pulmonary embolism at admission. Methods One hundred and seventy-seven patients with hemodynamically stable pulmonary embolism were retrospectively ...
Ouyang Xiaoli, Zhao Huijun, Chen Juping
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Skin Ultrastructure and the Changes of HIF-2α, H-FABP Expression in the Myocardium of Electric Shock Death Rats [PDF]
, 2021 Objective To observe the skin ultrastructure change of electric shock death rats and to test the expression changes of hypoxia-inducible factor-2α （HIF-2α） and heart type-fatty acid-binding protein （H-FABP） of myocardial cells, in order to provide basis ...
FENG Guo-wei, LIU Xia, QI Qian, et al.
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Harel-Yoon综合征一家系临床表型及ATAD3A基因变异分析
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2023 一例11 d女性新生儿因咳嗽伴口吐白沫、喂养困难就诊。实验室检查结果提示高乳酸血症，心肌损伤标志物升高，炎症指标升高，血串联质谱酰基肉碱检测辛酰基肉碱、癸酰基肉碱偏高。心脏超声及磁共振提示心功能不全、肥厚型心肌病。进一步完善家系全外显子测序，结果显示先证者及其姐姐均为ATAD3A基因c.1492dup（p.T498Nfs*13）和c.1376T>C（p.F459S）复合杂合变异，分别遗传自其父亲和母亲，诊断为Harel-Yoon综合征。先证者及其姐姐出生后均出现代谢性酸中毒、高乳酸血症、喂养困难 ...
Y. Zheng +5 more
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Evaluation of Cardiac Structure and Function in Patients with Wilson Disease Based on RT-3DE: a Clinical Study [PDF]
, 2023 Background Wilson disease (WD) is a rare autosomal recessive disease that causes impaired copper excretion, mainly manifestedashepatic and/or neuropsychiatric symptoms, but diversifies with the varying affected organs and severity of the disease.
ZHANG Yu, WANG Meixia, ZHANG Jing, WANG Fei, LI Zhonglei, ZHANG Yanyun, JIANG Zhenzhen
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Effect of phosphate binders on serum FGF-23 levels in maintenance hemodialysis patients with hyperphosphatemia [PDF]
, 2006 目的：近年来，许多研究显示高水平的FGF-23与肾脏疾病进展、心血管病死率及左心室肥厚相关。饮食磷限制及磷结合剂可用来控制磷酸盐平衡及升高的血清FGF-23水平。本研究的目的在于比较碳酸镧和碳酸钙对于维持性血液透析高磷血症患者血清FGF-23水平的影响。 方法：选取56例在我科行维持性血液透析治疗的慢性肾功能衰竭患者，所有患者维持性血液透析治疗超过3个月，接受血液透析治疗3次/周，每次4h，碳酸氢盐透析液钙离子浓度为2.5mEq/L。研究期间，患者的血液透析治疗方案保持不变。入选患者符合血磷＞1 ...
郭晓丹
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Correlation of serum activated protein C and 4⁃hydroxynonenal levels with myocardial injury in severe pneumonia and their prognostic prediction [PDF]
Objective To investigate the changes of serum activated protein C（APC）and 4 ⁃ hydroxynonenal（4 ⁃ HNE）levels in patients with severe pneumonia，and analyze their correlation with patient outcomes and myocardial injury.
GAO Tian*，WANG Wei，WANG Ling，QIAN li，HAN fei，WANG Shuo，YE Xiaoman，YIN Jie，ZHAI Aiqin
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Predictive value of Clinical Frailty Scale in long term prognosis of patients with acute myocardial infarction after in-hospital cardiac rehabilitation [PDF]
Objective·To investigate the predictive value of the Clinical Frailty Scale (CFS) in the long term outcomes in acute myocardial infarction (AMI) patients who completed in-hospital cardiac rehabilitation (CR).Methods·A total of 501 AMI patients treated in
DANZENG Quyang +7 more
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The preliminary study of the High-density Lipoprotein (HDL - C) changes on Myocarditis and possible mechanism [PDF]
, 2017 【目的】心肌炎是指各种原因引起的心肌的炎症性病变，轻症患者无任何症状，而重症患者可发生心力衰竭、心源性休克甚至猝死，目前其发病机制仍未完全明确，临床上也没有特异性的治疗手段。血脂代谢紊乱在动脉硬化性心血管病中的研究较多，但在心肌炎中的作用研究较少。本课题拟对心肌炎中的血脂代谢情况进行初步探讨，并进一步与心肌炎的炎症程度进行相关性分析，为心肌炎诊断和治疗提供新思路。 【方法】本研究分两部分内容：（一）临床研究：选取2013-2016年入住我院诊断明确的急性心肌炎患者，对照组选取健康体检患者 ...
吴阳
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Zhongguo shiyan zhenduanxue, 2022 缺血性心脏病是我国心血管疾病中致死率排名第二的疾病，目前发病率呈现逐年上升的趋势[1]。心肌严重缺血可能会导致急性心肌梗死的发生，并可引起室间隔穿孔、二尖瓣关闭不全、室壁瘤等严重并发症[2]，致死率高达50%以上。临床上常用的心肌梗死诊断方法包括血液化验和心电图检查，血液化验心肌损伤标志物以及心肌酶学应用最为广泛。肌钙蛋白被认为在心肌梗死的诊断中特异性和敏感性较高，但肌钙蛋白通常在发病24h达到高峰[3]，不适合心肌梗死的急性期诊断，可能会延误此类患者的早期临床干预。
汪雪, 王新新, 纪天亮, 徐彩霞
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