Results 111 to 120 of about 8,006 (148)

黄芪甲苷通过抑制STING通路减轻D-半乳糖诱导的心肌细胞衰老和凋亡

Zhongshan Daxue xuebao. Yixue kexue ban
目的探讨黄芪甲苷（AS-Ⅳ）对D-半乳糖（D-gal）诱导的心肌细胞衰老的保护作用及其潜在机制。方法以心肌细胞H9C2为模型，采用D-gal诱导心肌细胞衰老，通过CCK-8法检测细胞活力，β-半乳糖苷酶（SA-β-Gal）染色评估细胞衰老程度，ROS检测细胞内活性氧水平，TUNEL检测细胞凋亡程度，qRT-PCR和Western blot检测衰老相关基因和蛋白（p21、p53）及干扰素基因刺激因子（STING）通路关键基因（STING、CXCL10和 MX-1）和蛋白（STING、cGAS、p-IRF3/
郭文玉, 高佳佳, 段玮丽, 阮焕钧, 黄于朗, 王珂妹, 柯晓   +6 more
doaj  

Exosomal let-7a-5p derived from human umbilical cord mesenchymal stem cells alleviates coxsackievirus B3-induced cardiomyocyte ferroptosis via the SMAD2/ZFP36 signal axis. [PDF]

J Zhejiang Univ Sci B
Li X, Hu Y, Wu Y, Yang Z, Liu Y, Liu H.
europepmc   +1 more source

[Expression of the melanoma 2-mediated pyroptosis pathway in peripheral blood mononuclear cells of patients with idiopathic inflammatory myopathies]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Chu J, Li P, Tian J, Fu D, Guo L, Sun R, Li Y.   +6 more
europepmc   +1 more source

[Construction of cardiac organoids derived from human induced pluripotent stem cells for cardiac disease modeling and drug evaluation]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Gong X, Fan Y, Luo K, Yan Y, Li Z.
europepmc   +1 more source

[Liver-bone axis: novel mechanisms and strategies for MAFLD regulation]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Wang YW, Yan XZ, You H, Yang AT.
europepmc   +1 more source

[Extracellular matrix materials and tissue regeneration and repair]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhao L, Xie H.
europepmc   +1 more source

[A case of toxic shock syndrome secondary to severe bone marrow suppression induced by azathioprine in a patient with autoimmune hepatitis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ren Y, Kong M, Huang CY, Bian XQ, Liu HX, Mou DL, Chen Y.   +6 more
europepmc   +1 more source

[Application of Kartogenin in cartilage tissue engineering]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Jiang J, Zhang S, Lu W.
europepmc   +1 more source

[<i>Fuzheng Xiaoyan</i> Granules ameliorate cancer-related fatigue during breast cancer chemotherapy by regulating the AKT1/BAD/BCL-2 pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Sun X, Wang K, Wang G, Dai Q, Chen J, Kong X, Luan J.   +6 more
europepmc   +1 more source

[Identification and Underlying Mechanisms of Immune Cell- and Senescence-Related Biomarkers in Atrial Fibrillation]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Huang W, Liu E, Fu H.
europepmc   +1 more source