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Journal of Diabetes, Volume 15, Issue 8, Page 685-698, August 2023., 2023 Highlights Vascular complication is one of the most important causes of death in diabetes patients. Arterial stiffness plays a key role in the progress of diabetes vascular complication; therefore, the improvement of arterial stiffness could inhibit the process of atherosclerosis and reduce the burden of diabetes vascular complications This study first
Jincheng Wang +14 more
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Journal of Diabetes, Volume 15, Issue 7, Page 545-556, July 2023., 2023 Highlights High stress hyperglycemia ratio (SHR) was associated with elevated systematic inflammation in diabetic inpatients with pneumonia on admission. In the absence of hypoglycemia on admission, SHR was of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity.
Bing Liu, Yu Chen, Liping Yu, Min Zhou
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Journal of Diabetes, Volume 15, Issue 7, Page 557-568, July 2023., 2023 Highlights The association between stress hyperglycemia ratio (SHR) and long‐term outcomes was still controversial. Based on a large prospective multicenter cohort, we found that high SHR levels were independently associated with increased risk of major adverse cardiovascular events (MACE), all‐cause death, and unplanned revascularization. Associations
Guyu Zeng +18 more
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Journal of Diabetes, Volume 15, Issue 5, Page 368-381, May 2023., 2023 Highlights This study is the first registered meta‐analysis with three different insights to explore the relationship between the glycated hemoglobin (HbA1c) variability and the risk of cardiovascular disease (CVD). Our study suggests that the higher glucose fluctuation is significantly associated with the higher CVD risk in diabetes patients based on ...
Feng Li +6 more
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Studies of the regulatory mechanism on myocardial related genes of Rbm24 [PDF]
, 2015 实验目的 研究在心肌细胞分化和发育过程中，Rbm24蛋白发挥功能和产生的影响。寻找Rbm24结合的相关基因的不同水平的RNA，以及结合目的RNA后所发挥的功能，为降低Rbm24的表达导致扩张性心肌病等一系列心肌受损和功能紊乱相关疾病探究原因，寻找相关的信号通路，提供一定的实验及理论依据，为成功解决心脏疾病难题寻找重要的攻克点。 方法 通过Westernblot免疫印迹检测Rbm24和其他心肌相关蛋白在C2C12细胞分化中蛋白的表达情况 ...
杨康
core
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 303-310, March 2025.ABSTRACT Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular disease that occurs earlier in life.
M. Charakida +6 more
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Zhongguo shiyan zhenduanxue, 2022 血管壁内结构和功能发生不良改变是动脉硬化最早出现的表现，也是冠状动脉疾病、颈动脉疾病和外周动脉疾病最常见原因[1]。研究表明，动脉僵硬度(AS)是一个独立的心血管疾病预测指标。目前，临床上应用的衡量动脉僵硬度的方法主要有以下几种[2]：中心动脉压(CBP)、脉压(CPP)、增强指数(AIx)、脉搏波传导速度(PWV)、心血管磁共振(CMR)、心踝指数(CAVI)。本文对以上几种方法在心血管相关疾病中的研究进展做一综述。
史敬, 孙莹, 董春哲
doaj
Hypolipemic, hepatoprotective effect and the related mechanism of wedelolactone [PDF]
, 2015 目的：蟛蜞菊内酯属于呋喃香豆素类，据文献报道其具有抑制肝细胞纤维化、抗炎、 免疫调节、抗绝经后骨质疏松等作用，本文首次探讨蟛蜞菊内酯的降血脂作用及相关机 制。方法：首先通过体外实验观察蟛蜞菊内酯对脂质代谢相关基因和蛋白表达的影响。 HepG2细胞给药24h，提取蛋白及RNA，采用蛋白印迹法测定腺苷酸活化蛋白激酶 (AMPK)和过氧化物酶体增殖物活化受体α（PPARα）的蛋白表达水平，用实时荧光定量 PCR方法检测AMPK、PPARα、低密度脂蛋白受体（LDLR）以及脂蛋白脂酶(LPL)基因 表达水平 ...
彭璐
core
Suggestions for Chinese Dietary Lipids Reference Intakes in the New Period [PDF]
, 2022 With the rapid development of economy and society, the dietary pattern of Chinese residents has undergone obvious transition. The recommendation of dietary lipids intake has a significant influence on the improvement of dietary pattern and on the ...
JIA Shan-shan, PANG Shao-jie, ZHANG Jian
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 1, Page 85-93, January 2025.ABSTRACT Objective Accurate differentiation between placenta accreta spectrum (PAS) and uterine‐scar dehiscence with underlying non‐adherent placenta is often challenging, even for PAS experts, both prenatally and intraoperatively. We investigated the use of standardized two‐dimensional grayscale ultrasound and Doppler imaging markers in ...
T. Adu‐Bredu +3 more
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