Results 1 to 10 of about 1,279 (160)

[Mechanism of Extracellular Histone-Induced Endothelial Dysfunction Leading to Sepsis-Induced Acute Respiratory Distress Syndrome]. [PDF]

open access: yesSichuan Da Xue Xue Bao Yi Xue Ban
目的 揭示组蛋白引起内皮功能障碍致脓毒症急性呼吸窘迫综合征的机制,为靶向组蛋白治疗脓毒症急性呼吸窘迫综合征提供实验依据。 方法 体外实验首先采用梯度浓度组蛋白刺激人脐静脉内皮细胞(human umbilical vein endothelial cells, HUVEC),探索体外最佳刺激浓度。进而采用组蛋白刺激HUVEC 24 h进行造模,将细胞分为:①空白对照组、②空白对照+瑞沙托维(Toll样受体4抑制剂)干预组、③组蛋白刺激组、④组蛋白+瑞沙托维干预组。使用流式细胞术测定HUVEC凋亡情况 ...
Yang T, Li Y, Su B.
europepmc   +2 more sources

2019 新型冠状病毒肺炎重症病例临床特点分析 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】探讨并分析新型冠状病毒肺炎重症病例的临床特点,以提高对该病的认识。【方法】回顾分析我院收治的1例新型冠状病毒肺炎重症病例特点,包括一般资料、临床表现、实验室检验结果、胸部影像、治疗、并发症及预后,讨论重症病例的临床特点。【结果】该例新型冠状病毒肺炎确诊病例为61岁男性,有基础疾病。临床表现包括发热、咳嗽、乏力与气促。检验结果示白细胞不高,淋巴细胞总数降低,乳酸脱氢酶升高及低氧血症。胸部影像示双肺炎性渗出。经1周支持、抗感染、抗炎、免疫调节等治疗后病情仍进行性加重,并发重度急性呼吸窘迫综合征 ...
石云锋   +7 more
doaj   +2 more sources

Ghrelin 预处理骨髓间充质干细胞来源上清液对内皮细胞增殖、迁移及凋亡的影响 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】研究生长激素释放肽(ghrelin)预处理骨髓间充质干细胞(BMSCs)来源上清液对内皮细胞增殖、迁移及凋亡的影响,并初步探索其作用机制。【方法】全骨髓贴壁分离法提取大鼠BMSCs,利用流式细胞术鉴定 BMSCs 表面分子标记。收集 BMSCs 上清液及高、中、低浓度(100 nmol/L、10 nmol/L、1 nmol/L)ghrelin 预处理BMSCs 24 h 后上清液,以无血清培养基为对照,将上清液分别加入人脐静脉细胞融合细胞(EA.hy926)作用24 h, 利用 CCK8 ...
葛珊慧, 张莉珊, 林山, 曾勉
doaj   +2 more sources

Application of Biomarker Detection of Exhaled Air Condensate in Respiratory Diseases [PDF]

open access: yes, 2022
Respiratory diseases are getting more and more attention, and their complex and changeable symptoms have brought a series of challenges to medical treatment.
XU Baichuan, LI Yiting, ZHAO Hulei, ZHANG Peng, XIE Yang
core   +1 more source

Nursing experience of non-invasive ventilation in prone position for a patient with acute respiratory distress syndrome combined with COVID-19 (1例新型冠状病毒肺炎合并急性呼吸窘迫综合征患者俯卧位无创通气护理体会)

open access: yes中西医结合护理, 2021
This paper summarized the nursing experience of non-invasive ventilation in prone position for a patient with acute respiratory distress syndrome combined with COVID-19.
WANG Jijun (王吉军)   +2 more
doaj   +1 more source

COVID‐19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity? 新冠肺炎与合并症:二肽基肽酶4在疾病严重程度中的作用?

open access: yesJournal of Diabetes, Volume 12, Issue 9, Page 649-658, September 2020., 2020
Highlights Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2; recent modeling of the structure of SARS‐CoV‐2 spike glycoprotein, which mediates viral‐host‐cell entry, predicts interactions with dipeptidyl peptidase 4 (DPP4) in addition to angiotensin‐converting enzyme 2.
Margaret F. Bassendine   +3 more
wiley   +1 more source

Human respiratory CO2 concentration monitoring model and its experimental verification [PDF]

open access: yes, 2021
Aiming at the monitoring of the concentration of human respiratory CO2, this paper reasonably simplifies the human respiratory process from the perspective of physics. Based on the gas exchange in the lungs during respiratory process and the relationship
Guo, Zhurui   +4 more
core   +2 more sources

Application and nursing of prone ventilation technique in ICU (俯卧位通气技术在ICU的应用及护理)

open access: yes中西医结合护理, 2023
Objective To explore the therapeutic effect and nursing experience of patients with respiratory failure in ICU after prone ventilation. Methods From January 2020 to January 2021, 4 patients with acute respiratory distress syndrome (ARDS) and 1 patient ...
DAI Hongran (代洪然)   +3 more
doaj   +1 more source

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