Role and research progress of transient receptor potential vanilloid-1 in acute respiratory distress syndrome [PDF]
Acute respiratory distress syndrome (ARDS) is a severe critical respiratory disease characterized by refractory hypoxemia, which is caused by intrapulmonary and extrapulmonary factors. It has a rapid onset, and high morbidity and mortality.
DU Hailei +4 more
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Correlation of peripheral blood ZO⁃1 and IL⁃38 levels with lung injury degree in patients with acute respiratory distress syndrome [PDF]
Objective To analyze the changes of zonula occludens⁃1（ZO⁃1）and interleukin⁃38（IL⁃38）levels in peripheral blood of acute respiratory distress syndrome（ARDS）patients with different degrees of lung injury，and their correlations with the degree of lung ...
HE Yanxia，XUE Bing，WU Wenjie，CHEN Xing
core +2 more sources
Clinical effect of damage-control orthopedics in the treatment of severe pelvic fracture [PDF]
, 2015 目的探讨骨科损伤控制(dCO)治疗严重骨盆骨折的临床效果。方法回顾性分析本院2010年1月~2014年1月收治的201例严重骨盆骨折患者临床资料,其中采用dCO治疗的患者为试验组(n=104),未采用dCO治疗的患者为对照组(n=97),观察两组的院内死亡率、手术时间、术中失血量、术中输液总量、术后并发症发生率和6 H乳酸清除率。结果试验组、对照组分别有7例(6.7%)和22例(22.7%)死亡,死亡原因均为失血性休克和多器官功能不全综合征,两组院内死亡率比较差异有统计学意义(P=0.003 ...
唐旭华 +4 more
core
The effect of glucocorticoids combined with ulinastatin on IL⁃6/IL⁃10 balance and oxygenation index in patients with early acute lung injury after trauma [PDF]
Objective To investigate the clinical efficacy of glucocorticoid combined with ulinastatin in patients with early acute lung injury（ALI）after trauma. Methods A total of 100 patients with early ALI after trauma who admitted to Shengjing Hospital of China ...
LI Tang，WANG Yudong，LI Wenchao
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A case report of heat stroke with early severe brain edema [PDF]
, 2023 Heat stroke can be divided into two types: exertional and classic, mainly manifested as a clear history of exposure to hot temperature/high heat environment or intense physical activity in hot environment, core temperature exceeding 40 ℃, accompanied by ...
Liya PAN, Shisheng LUO, Tuoying WEN
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中西医结合护理, 2023 This paper summarized the prone position ventilation and nursing management for a patient with influenza A (H1N1)virus infection combined with hypermucoviscous Klebsiella pneumoniae infection.
WEI Xian (魏娴) +4 more
doaj +1 more source
The relationship between serum IL⁃33，vWF，G⁃CSF and prognosis of acute massive hemorrhage patients with transfusion⁃related acute lung injury [PDF]
Objective To explore the predictive value of serum interleukin⁃33（IL⁃33），von Willebrand factor（vWF），and granulocyte colony⁃stimulating factor（G⁃CSF）for the prognosis of acute massive hemorrhage patients withtransfusion⁃related acute lung injury（TRALI ...
DU Dan*，WEI Ge，WANG Lingxue，LIU Hongbin
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Zhongguo shiyan zhenduanxue, 2017 急性肺损伤（ALI）和急性呼吸窘迫综合征（ARDS）是指心源性以外的各种肺内、外致病因素导致的急性、进行性、缺氧性急性呼吸衰竭。急性肺损伤最严重的情况就是急性呼吸窘迫综合征[1]。流行病学调查显示ALI/ARDS是临床常见危重症,其发病机制目前尚不清楚,缺少敏感、特异的指标,使得治疗上的总体预后改善并不大,因此动物模型为研究急性肺损伤提供了较大帮助。目前研究急性肺损伤的动物模型有鼠类、兔、犬、猪、绵羊、山羊及灵长类等动物,但由于动物和人的肺部解剖结构和对抗损伤的防御机制不同 ...
刘泽茹, 宋磊, 李丹
doaj
Effects and mechanisms of Pd-Ia on LPS-induced acute lung injury in mice [PDF]
, 2016 目的：随着环境的不断恶化，空气质量越来越差，并且已经严重影响到了人们的身体健康，雾霾已经遍布中国的众多城市，使得呼吸系统疾病的发病率日渐升高。急性肺损伤（ALI）/急性呼吸窘迫综合征（ARDS）都是比较常见的临床呼吸系统疾病，ARDS对于临床疾病来说，可谓是灾难性的，属于严重的呼吸衰竭，目前无有效的药物治疗措施。ALI是ARDS的早期阶段，其特点是弥漫性的炎症损伤，目前研究发现中药白花前胡根中提取出的活性成分白花前胡甲素（Pd-Ia）在LPS诱导的内皮细胞炎症损伤中具有良好的抗炎效果 ...
周晓霞
core
适应性支持通气在急性呼吸窘迫综合征中实施肺保护性通气策略的应用研究
Zhongguo shiyan zhenduanxue, 2012 目的研究适应性支持通气（ASV）在急性呼吸窘迫综合征（ARDS）中实施肺保护通气策略的应用,并探讨其优越性。方法 60例ARDS机械通气患者随机分为ASV组和PSIMV组,均实行肺保护通气策略,比较两组患者呼吸力学、血气及血流动力学各指标的变化。结果通气24小时后,ASV组较PSIMV组气道峰压（PIP）、平台压（Pplat）显著降低（P0.05）;两组治疗24小时后Pa02、氧合指数、静态肺顺应性较治疗前均明显改善 ...
陈少霖 +5 more
doaj