Results 91 to 100 of about 2,535 (167)
Machine learning model predicts the occurrence of acute kidney injury after open surgery for abdominal aortic aneurysm repair. [PDF]
Sheng C, Liao M, Zhou H, Yang P.
europepmc +1 more source
Gadd45b mediates TGF-β induced podocytes injury [PDF]
局灶节段性肾小球硬化(focalsegmentalglomerularsclerosis,FSGS)是儿童和成年人肾病综合征的常见原因,其发病率逐年上升。FSGS患者临床表现为大量蛋白尿,病理表现为足细胞不同程度的损伤。患者易并发感染、静脉血栓以及急性肾损伤,部分患者激素治疗效果不理想,进展为终末期肾病(endstagerenaldisease,ESRD)。FSGS足细胞损伤机制尚不清楚。因此本研究从足细胞损伤机制入手,讨论其可能的损伤机制,以加深对该疾病的认识。 第一部分 ...
陈萍
core
目的探讨尿中性粒细胞明胶酶相关脂质运载蛋白(NGAL)检测对急性肾小球肾炎(AGN)早期肾损伤诊断的临床意义。方法选择120例2015年1月-2016年5月确诊为AGN的患者进行尿NGAL和血清胱抑素C(Cystatin C,Cys-C)浓度水平检测,对结果进行综合分析。结果实验组患者的尿NGAL和血清Cys-C浓度水平明显高于对照组,差异具有统计学意义 ...
黄向阳
doaj
Knockout of farnesoid X receptor gene aggravates cisplatin-induced kidney injury. [PDF]
Zhang L, Li A, Huang Z, Wang Y, Yi B.
europepmc +1 more source
急性肾损伤(acute kidney injury,AKI)是临床上较为危重的急症,多继发于重度心力衰竭、心源性休克、急性重症胰腺炎等疾病。血液透析(hemodialysis,HD)是临床上治疗肾衰竭最常用的方式,能够有效清除体内中小分子毒素[1]。但是HD的缺点是对大分子毒素的清除能力较弱,血流动力学波动较大,整体疗效并不理想。连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)是近年来发展起来的AKI治疗方式 ...
王妍妮, 解建国
doaj
A clinical study of acute kidney injury in children with type 1 diabetes and diabetic ketoacidosis. [PDF]
Yuan XW, Wang X, Tang N, Xie H, Gu W.
europepmc +1 more source
Research progress in hypothermia-induced RBM3 in ischemia-reperfusion injury of various organs [PDF]
Ischemia-reperfusion injury (IRI) is a complex hemodynamic disorder with high mortality rates and limited treatment options. Mild hypothermia is a widely-accepted treatment method for alleviating ischemic and hypoxic injury, especially in the study of ...
Sun Luxuan, Dang Xiaoping, Sun Zijian
core +1 more source
目的观察缺血再灌注损伤对肾细胞游离钙([Ca2+]i)水平和细胞凋亡的影响。方法采用摘除左肾,钳夹大鼠右侧肾蒂,建立急性缺血再灌注肾损伤模型,应用Fura-2/AM荧光指示剂测定缺血再灌注大鼠肾细胞[Ca2+]i水平,流式细胞术检测肾细胞凋亡率。结果缺血再灌注不同时期肾细胞呈现不同程度Ca2+超载,与对照组相比差异显著 ...
赵军, 张文岚, 孙玲
doaj
[Risk factors for early acute kidney injury after cardiac arrest in children in the pediatric intensive care unit and a prognostic analysis]. [PDF]
Zhang XP +5 more
europepmc +1 more source
Research progress on the pathogenesis of primary membranous nephropathy [PDF]
This article reviews the pathogenesis of primary membranous nephropathy (PMN) in recent years, encompassing the latest findings of genetic, antigenic, environmental factors, and intestinal flora, etc., so as to provide a reference for further ...
CEN Tao +5 more
core +1 more source

