Results 31 to 40 of about 2,535 (167)
Association of extravascular lung water with clinical outcomes in stages 4 and 5 chronic kidney diseases: a prospective cohort study [PDF]
, 2023 Objective To evaluate the impact of extravascular lung water volume on cardiovascular events， renal replacement therapy and mortality in pre-dialysis patients with stages 4 and 5 chronic kidney diseases.
Wang Jiawei, Luo Qiong, Lu Laishun, Hong Chunyan, Tang Xiaoling
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Zhongguo shiyan zhenduanxue, 2014 Clusterin被发现与许多肾脏损伤有关,在肾缺血再灌注损伤、有明显排斥反应的肾移植患者以及一些药物导致的急性肾损伤中Clusterin表达均有上调[1],可作为肾损伤的分子生物标志物。单侧输尿管梗阻（uniliteral ureteral obstruction,UUO）能直接导致肾间质炎症和纤维化等多样性病理学改变,而Clusterin的表达与UUO造成早期肾损伤的关系尚未见详细报道 ...
黄秀英 +7 more
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The renoprotective effects and possible mechanism of aminoguanidine in mice with ischemia/reperfusion injury [PDF]
, 2011 缺血再灌注损伤(ischemicreperfusioninjury，IRI)是指组织或器官在缺血及重获血流灌注或氧供应后，对组织或器官产生的损伤作用。肾是高灌注器官，对缺血缺氧较为敏感，因此肾缺血—再灌注损伤在临床上较为常见。研究表明，肾缺血—再灌注损伤是引起急性肾衰竭（acuterenalfailure，ARF）和慢性肾衰竭（chronicrenalfailure，CRF）的主要原因。但是缺血再灌注肾损伤的发病机制至今尚未完全阐明。因此，明确肾缺血—再灌注损伤的发病机理 ...
徐波
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Analysis of risk factors of adverse pregnancy outcomes in patients with chronic kidney disease [PDF]
Objective·To find out the risk factors leading to adverse pregnancy outcome by analyzing the correlation of clinical data and adverse pregnancy outcomes in patients with pregnancy complicated with chronic kidney disease.Methods·The clinical data before ...
LI Yu, ZHANG Yu
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Zhongguo shiyan zhenduanxue, 2014 急性肾损伤（AKI）是近年来提出用于取代使用多年的急性肾衰竭（ARF）的一个新名词,并已获得广泛认可[1]。是一种临床常见的危急重症,其病因复杂,临床表现多样,病情变化快[2]。如果不早期寻找病因、积极治疗,预后极差。因此,我们探讨急性肾损伤患者肾穿刺活检临床病理特点,以期早期诊断、积极合理治疗、改善预后 ...
王雁德, 刘树军, 刘淑香
doaj
Effects of different therapeutic doses of CRRT on serum PGE2 and I⁃FABP levels and prognosis in patients with severe sepsis [PDF]
"Objective To analyze the effects of continuous renal replacement therapy（CRRT） dose on serum prostaglandin⁃2（PGE2）and intestinal fatty acid⁃binding protein（I⁃FABP）levels and prognosis in patients with severe sepsis，and to reveal the dynamic pattern of ...
XIAO Hui，LI Shanglin，FENG Xincheng，TONG Xia
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Effect of silencing LC3 on apoptosis of mouse hepatocellular carcinoma Heap1-6 cells [PDF]
, 2017 目的建立小鼠LC3基因沉默的Heap1-6稳定表达细胞系，探讨其对衣霉素诱导的肝癌细胞凋亡的影响。方法设计并合成一段针对小鼠LC3基因的shRNA及不针对任何基因的shRNA作为阴性对照，将它们退火后连接构建重组载体，转化扩增及酶切鉴定之后将重组质粒与病毒包装、包膜质粒共同转染293T，收集病毒上清转染Heap1-6细胞，嘌呤霉素筛选10 d，获得稳定的细胞株。以导入LC3基因shRNA的Heap1-6为实验组（Heap1-6 shLC3），以导入shcoo2的Heap1-6为对照组（Heap1-6 ...
任冰霜 +5 more
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Zhongguo shiyan zhenduanxue, 2018 急性肾损伤（AKI）在老年患者中的发病率尤为显著[1]。与年轻患者比较,老年患者发生AKI后进展为慢性肾脏病或终末期肾脏病的风险高,住院期间的死亡率也相对较高[2]。目前,AKI仍是肾活检的主要指征[3]。研究表明与年轻患者比较,老年急性肾损伤患者进行肾活检不仅安全可靠而且更具有临床意义[4]。急性间质性肾炎（AIN）是AKI最常见也是最重要的病因 ...
杨帆, 刘娟, 吴淋淋
doaj
一例热射病合并多器官功能障碍综合征患者的营养支持方案分析 [PDF]
, 2019 目的:对1例热射病合并多器官功能障碍综合征患者的营养支持方案进行分析。方法:临床药师参与1例热射病合并多器官功能障碍综合征患者的用药治疗,并协助医师制定营养支持方案。结果:患者经过12 d的营养支持及综合治疗,肝肾功能逐步恢复正常,无明显相关并发症,胃肠道功能恢复良好,营养支持效果良好。结论:在热射病规范治疗方案的基础上 ...
张云琛 +5 more
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In Vitro Nephrotoxicity of Migrants from Polybutylene adipate-co-terephthalate-Modified Starch Composite Material [PDF]
To investigate the nephrotoxicity of polybutylene adipate-co-terephthalate (PBAT)-modified starch composite material, substances migrating to different food simulants (4% acetic acid, 10% ethanol, and 95% ethanol) from the composite material were ...
WANG Xukai, CHEN Congying, RANG Yifeng, XIAO Xueman, LI Yinhuan, WANG Junming, LIU Chunhong
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