Results 61 to 70 of about 2,535 (167)
Associations between serum complement component 3a and sC5b⁃9 levels with the prognosis of sepsis patients [PDF]
"Objective To investigate the associations of serum complement component 3a（C3a）and soluble terminalcomplement complex C5b⁃9（sC5b⁃9）levels with the severity of sepsis and 28⁃day clinical prognosis among patients，and to provide new biomarker references ...
SU Yixing，BAO Lei，YU Jun'an，GU Zhijian
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Zhongguo shiyan zhenduanxue, 2019 目的分析4类尿液生物标记物(尿N-乙酰-β-D-氨基葡萄糖苷酶、肝脏型尿脂肪酸结合蛋白、尿富半胱氨酸蛋白61、尿胎球蛋白A)联合血清指标(血肌酐、血尿素氮)在急性肾损伤中的应用价值。方法选取我院2014年3月-2016年3月收治的98例急性肾损伤患者作为观察组,另选同期105例健康体检者为对照组,在征得两组受试者知情同意下对其4类尿液生物标记物和血清指标进行检测与比较。结果观察组4类尿液生物标记物、血清指标均高于对照组,差异有统计学意义(P2期>1期且差异有统计学意义 ...
王洋一, 陈婷
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Research advances Progress in mechanistic studies of renal fibrosis based upon regulatory cell death [PDF]
As a basic pathological feature at advanced stage of various kidney diseases, renal fibrosis (RF) is an important cause of kidney failure. It is characterized by an excessive accumulation of extracellular matrix (ECM), damage of renal tissue structure ...
Guang-ming Yin +5 more
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联合检测胱抑素C和同型半胱氨酸对早期急性肾损伤辅助诊断的临床意义
Zhongguo shiyan zhenduanxue, 2017 急性肾损伤是临床常见的肾功能急性减退性综合征,危害性较大,临床表现不一,早期可无明显临床症状,急性肾小管坏死是其常见类型,典型的临床表现分为Ⅰ、Ⅱ、Ⅲ期,患者若未及时得到确诊和治疗造成病情延误,可能导致代谢性酸中毒、肾衰竭等,危及生命安全[1 ...
刘晓萍, 张召涛
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Advances in intensive antihypertensive treatment in hypertensive patients complicated with cardiovascular disease [PDF]
Hypertension is a serious public health problem worldwide and a major risk factor for cardiovascular disease. Hypertensive patients are constantly complicated with cardiovascular disease.
Zhang Rongzhen, Jia Min, Lou Doudou, Wang Xiaoxiao, Wang Liang, Wang Rutao, Tao Ling
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Clusterin在庆大霉素诱导的急性肾损伤大鼠模型中的表达及诊断意义
Zhongguo shiyan zhenduanxue, 2014 Clusterin是体内一种异二聚体糖蛋白,最初见于公羊睾丸液,作用为促细胞聚集。其后陆续研究发现Clusterin参与许多重要生理过程:细胞周期调控、DNA的损伤修复和组织修复等,具有辅助生殖、脂质转运、抑制补体介导的细胞免疫等功能[1],还与调控细胞凋亡有关[2]。为进一步明确尿中Clusterin水平与在急性肾损伤中的诊断意义[3,4],本研究建立大鼠庆大霉素急性肾损伤模型 ...
耿嘉男 +7 more
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Development of a prediction model for acute respiratory distress syndrome in ICU patients with acute pancreatitis based on machine learning algorithms [PDF]
"Objective To develop and validate a predictive model based on machine learning algorithms to assess the risk of acute respiratory distress syndrome（ARDS）in patients with acute pancreatitis（AP）admitted to the intensive care unit（ICU）.
REN Xia*，LIU Luojie，ZHA Junjie，YE Ye，XU Xiaodan，YE Hongwei，ZHANG Yan
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Zhongguo shiyan zhenduanxue, 2017 急性肾损伤（AKI）具有高发病率、高死亡率以及给患者带来的沉重的经济负担的特点[1,2]。AKI是一种频发的临床综合征。是一种危急重症,其病因复杂,临床表现多样,病情变化快。AKI的主要特征是在数小时至数周内肾功能急剧恶化,造成新陈代谢失调、电解质紊乱及液体失衡[3]。AKI分肾后性AKI、肾性AKI、肾前性AKI[4]三类 ...
封文媛 +3 more
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Zhongguo shiyan zhenduanxue, 2012 AQP2是特异性表达在集合管上皮细胞膜上水通道蛋白,影响原尿重吸收、浓缩、稀释的重要转运通道,在肾脏缺血-再灌注损伤后12-48小时表达显著减低,且与缺血时间呈正相关[1]。本研究从分子学上探讨大鼠肾缺血-再灌注损伤（IRI）后肾脏集合管AQP2的表达和吸入麻醉剂七氟醚预处理对急性肾缺血再灌注损伤的保护作用。1材料与方法1.1实验动物、模型建立及分组8-12周健康SD雄性大鼠 ...
高凤, 赵国庆, 王伟华, 李龙云
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