Predictive value of cystatin C-based estimated glomerular filtration rate combined with thromboelastogram for clinical prognosis of acute-on-chronic liver failure [PDF]
, 2023 Objective To investigate the value of cystatin C-based estimated glomerular filtration rate （eGFR-CysC） combined with thromboelastogram （TEG） to predict clinical prognosis of patients with acute-on-chronic liver failure （ACLF）.
Ba Zhiwei, Zhao Wen, Liu Chuanmiao
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HBV相关肝衰竭患者Th1/Th2型细胞因子变化及与预后的关系
Zhongguo shiyan zhenduanxue, 2023 目的 探讨Th1/Th2型细胞因子在乙型肝炎病毒(HBV)相关慢加急性肝衰竭(HBV-ACLF)患者中的表达变化及与预后的相关性。方法 回顾性分析2021年1月至2021年12月HBV-ACLF患者69例与慢性乙型肝炎(CHB)患者70例的临床资料，并选择同期体检的70例健康人员为对照组，比较3组对象血清Th1/Th2型细胞因子表达，并比较HBV-ACLF组不同病情程度及预后患者血清Th1/Th2型细胞因子表达水平差异。结果 HBV-ACLF组患者血清IL-2、INF-、TNF-α、IL ...
刘艳丽 +5 more
doaj
基于生物信息学途径探究载脂蛋白 H 在肝衰竭中的功能及作用机制 [PDF]
, 2020 【目的】通过生物信息学方法，分析在肝衰竭中高表达的载脂蛋白H（APOH）在疾病发生发展中的功能与机制。【方法】从GEO数据库下载多个芯片数据集（GSE14688、GSE38941和GSE96851），以5筛选出差异表达基因，通过Cytoscape及R对前10位关键基因中的APOH基因进行GO生物学功能富集分析和KEGG信号通路分析，并进一步在慢乙肝相关肝衰竭组织中进行表达验证。【结果】共筛选出2438个差异表达基因，其中，1162个上调基因，1276个下调基因 ...
于明雪 +6 more
core
肝血管肉瘤是一种罕见、高度恶性、起源于肝脏血管或淋巴管的肿瘤，其临床表现及影像检查无特异性，需要病理活检确诊。本文报道一例47岁男性肝血管肉瘤患者，其以腹痛、黄疸、弥散性血管内凝血等为临床表现，且CT、MRI等影像酷似肝窦阻塞综合征。同时，本文回顾了近年肝血管肉瘤的相关文献，对肝血管肉瘤的表现、诊断及治疗等方面总结 ...
唐承薇, 张林昊, 黄志寅
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Analysis of liver function，coagulation function，and complications in patients with low viral load HBV⁃related cirrhosis [PDF]
"Objective To investigate the characteristics of liver function，coagulation function，and complications in patients with low viral load hepatitis B virus（HBV）-related cirrhosis.Methods A retrospective study was conducted in 108 patients with low viral ...
MA Hongfei*，LI Jingran，ZHANG Mei
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Predictive value of TEG for deep venous thrombosis of lower limbs in patients with chronic obstructive pulmonary disease [PDF]
Objective To analyze the value of thromboelastogram （TEG） parameters in predicting deep venous thrombosis of the lower limbs in patients with chronic obstructive pulmonary disease（COPD）.
Tan Huaqiao, Bin Dongmei, Zhou Jieliang, Shao Chaohua, Pei Hua, Huang Weihua, Liu Xiaojuan
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Analysis of changes and influencing factors of activation rate of peripheral blood monocytes after liver transplantation [PDF]
ObjectiveTo analyze the effect of the activation rate of peripheral blood monocytes on the recovery of patients after liver transplantation and to initially explore the possible influencing factors for differences in monocyte activation rates.MethodsA ...
Hui WU +4 more
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Analysis of mortality risk factors in pregnant women with liver failure. [PDF]
, 2013 目的:探讨肝衰竭孕妇的死亡危险因素。方法:回顾分析2002年7月至2011年8月我院收治的43例妊娠合并肝衰竭患者的临床资料,根据患者的结局分为存活组(27例)和死亡组(16例)。采用单因素分析和二元变量lOgISTIC逐步回归筛选相关的危险因素。结果:妊娠合并肝衰竭患者的病死率为37.21%(16/43),病原学以HbV感染多见(17/43),以无慢性肝病基础的急性和亚急性肝衰竭占多数(26/43)。死亡组的总胆红素(TbIl)、白蛋白(Alb)、凝血酶原活动度(PTA)、感染、≥Ⅱ级肝性脑病 ...
曹健英, 蒋佩茹, 陈宝花
core
肝移植是目前临床上用于治疗终末期肝病患者最佳手段。多年来，经过广大专家学者们前赴后继的努力，肝移植技术在不断创新与发展。中国肝移植团队在临床领域取得了一系列重大进展。器官移植已进入2.0时代，无缺血器官移植已拓展至心、肺、肾等多个移植领域，具有广阔的应用前景。无缺血肝移植（IFLT）通过创新性地维持供肝在获取、保存及移植过程中的连续血流灌注，避免了传统肝移植中因缺血再灌注损伤引发的细胞损伤和术后并发症，成为器官移植领域的革新性进展。此外，该技术为边缘供肝（如高龄供肝、脂肪肝）的利用提供了新可能 ...
朱明强, 王小华
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The application of artificial intelligence in medical clinics, scientific research and education [PDF]
In recent years, artificial intelligence (AI) has developed rapidly, and clinical medicine has also seen revolutionary changes. This study traces the development process of AI in clinical medicine and conducts an in-depth analysis through specific ...
Diyuan QIN +12 more
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