【目的】探讨不同时相慢加急性乙肝肝衰竭患者外周血NK细胞及相关受体的表达特点。【方法】采 用流式细胞术检测各研究组,包括肝衰竭进展期组13例、平台期组33例、健康对照组13例的外周血NK细胞比例、 活化性受体NKG2D、NKp30、NKp46、抑制性受体NKG2A、KIR2DL1、KIR2DL3、KIR3DL1、杀伤功能相关因子Perforin、 GranzymeB、FasL 的表达情况。【结果】进展期患者 NK 细胞比例较平台期患者、正常人外周血 NK 细胞比例低 (P=0.021),正常人 ...
翁伟镇 +4 more
doaj
异体骨髓间充质干细胞治疗不同时相慢加急性乙肝肝衰竭患者的疗效
【目的】 探讨异体骨髓间充质干细胞治疗慢加急性乙肝肝衰竭患者合适时机?【方法】 91例慢加急性乙肝肝衰竭患者分为两大组,干细胞治疗组45例,其中进展期12例,平台期33例;对照组46例,进展期13例,平台期33例?首要研究终点是比较12周不同组不同期患者生存状况;次要研究终点是观察干细胞治疗组患者与对照组患者不同时点的胆红素?终末期肝病模型(MELD)评分变化情况?【结果】 与对照组相比,疾病进展期患者12周累积生存率(6/12, 50%)与对照组进展期患者生存率(6/13, 46.2 ...
翁伟镇
doaj
目的评估急性发作期慢性阻塞性肺病患者的营养状况与肺功能、动脉血气指标变化的关系,以预测慢性阻塞性肺病急性发作期患者的病程及预后。方法收集2008年3月至2009年3月因COPD急性加重(AECOPD)入住中日联谊医院呼吸内科53例患者,并除外肝、肾、消化道疾病及结核、恶性肿瘤、甲状腺功能亢进等消耗性疾病。依据轻度:FEV1 ...
王静, 徐震, 李立, 石少敏
doaj
Comparison of tenofovir alafenamide and entecavir for hepatitis B virus-related acute-on-chronic liver failure. [PDF]
Peng W +5 more
europepmc +1 more source
[Assessment Value of Short-Term Prognosis of Six Predictive Models for Patients with Acute-on-Chronic Liver Failure Treated with Artificial Liver Support System]. [PDF]
Ma YJ, Du LY, Bai L, Tang H.
europepmc +1 more source
[Clinical Value of Cystatin C-Based Estimated Glomerular Filtration Rate in Assessing Short-Term Mortality in Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure Treated with Artificial Liver Support System]. [PDF]
Wang L +9 more
europepmc +1 more source
[Liangxue Jiedu Huayu Formula improves liver function of mice with acute-on-chronic liver failure by inhibiting excessive activation of the cGAS-STING signaling pathway]. [PDF]
Tang Q +9 more
europepmc +1 more source
Value of serum tryptophan in stratified management of 90-day mortality risk in patients with hepatitis B virus-related acute-on-chronic liver failure: a multicenter retrospective study. [PDF]
Zhou C +9 more
europepmc +1 more source
[EVA1A overexpression improves non-alcoholic fatty liver disease in mice by regulating lipid metabolism and promoting lipophagy]. [PDF]
Xu J +8 more
europepmc +1 more source
[Advancing the development of hematology care units to enhance hematology‑specific critical care capacity]. [PDF]
Fan SJ, Li HT, Zhang X.
europepmc +1 more source

