Results 51 to 60 of about 2,183 (101)

基于CUMS模型探究抑郁症对细菌感染的影响及作用

Zhongshan Daxue xuebao. Yixue kexue ban
目的抑郁症是一种常见的精神疾病，对患者的身体健康有着深远的影响。抑郁症与较高的细菌感染风险相关；然而，这是否是一种因果关系，以及抑郁症如何影响感染仍不清楚。因此，本研究旨在通过构建慢性不可预测轻度应激（CUMS）模型，探究抑郁表型在小鼠细菌感染中的作用。方法小鼠经CUMS诱导4周，通过行为学测试评估抑郁表型。随后，小鼠腹腔注射肺炎克雷伯菌模拟细菌感染，感染后48 h收集血清和腹腔组织。苏木精-伊红染色（ HE）观察组织病理学改变，酶联免疫吸附试验（ELISA）检测炎性因子水平。此外 ...
徐磊, 赵润平, 陈洁云, 杨艳鲜, 郭锡龙, 代敏, 田国宝, 秦丽娜   +7 more
doaj  

[Application of multidisciplinary team diagnosis and treatment model in the management of patients with combined burns and heat stroke]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Jiang SS, Wang NN, Wang HH, Xiao R, Zhang SL, Wang C, Yan J, Hu DS, Duan SL, Lin ZC, Hu MY, Li S, Wang M, Lyu N, Ji YL, Feng Q, Li QH, Lin GA, Yan TT.   +18 more
europepmc   +1 more source

[Comprehensive management of tophaceous wound]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
He G, Lu S, Lu X, Liu Y.
europepmc   +1 more source

[NLRP3 signaling pathway promotes hepatocyte pyroptosis in mice with nonalcoholic steatohepatitis in hypoxic environment]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Luo S, Zhu Q, Yan Y, Ji Z, Zou H, Zhang R, Ba Y.   +6 more
europepmc   +1 more source

[Knockdown of <i>Cav1</i> inhibits mitochondrial function and mRNA m⁶A modification and expression of key genes in mouse hepatocytes]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Ding S, Liao Y, Bai X, Huang J, Asakawa T.   +4 more
europepmc   +1 more source

[Biological activities of <i>Polygonatum</i> polysaccharides and their roles in the prevention and treatment of related diseases]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Guan P, Li Z, Wang Q, Ding H, Chen L, Qin H.   +5 more
europepmc   +1 more source

胆汁性肾病的基础与临床研究进展 附视频

Linchuang shenzangbing zazhi
胆汁性肾病（cholemic nephropathy,CN）是在晚期慢性肝病并发重度黄疸患者中出现的一种以肾功能障碍为主要表现的疾病。目前，CN缺乏有效的无创诊断方法，肾穿刺活检是该病临床诊断的金标准。此外，该病常与肝肾综合征相混淆，漏诊或误诊易贻误治疗使得患者预后较差。CN的临床治疗原则是降低患者高胆红素水平以缓解肾损伤，若药物效果不佳也可采用人工肝系统改善患者肾功能。CN的病理机制尚未完全阐明，近年来的研究表明该病的发病机制包括肾脏转运体异常、胆汁酸损伤以及炎症反应等。基于此 ...
doaj  

[EVA1A overexpression improves non-alcoholic fatty liver disease in mice by regulating lipid metabolism and promoting lipophagy]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Xu J, Yang D, Zang K, Chu M, Zhao Q, Li Q, Lu S, Chen X, Li N.   +8 more
europepmc   +1 more source

[LncRNA Meg3 expression level is negatively correlated with liver fibrosis severity in patients with Wilson disease]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Hua D, Xuan Q, Sun L, Yu Q, Wang Q, Wang T, Ma Q, Yang W, Wang H.   +8 more
europepmc   +1 more source

[Clinical analysis of nine cases of hemophagocytic lymphohistiocytosis during pregnancy: characteristics, therapeutic strategies, and maternal-infant outcomes]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Liu YP, Miao Y, Li JY.
europepmc   +1 more source