Results 1 to 10 of about 9,212 (154)
Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach
Equine Veterinary Journal, Volume 55, Issue 6, Page 1012-1020, November 2023., 2023 Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien +6 more
wiley +1 more source
Advances in Chinese medicine-mediated AMPK/mTOR signaling pathway for the treatment of osteoporosis [PDF]
, 2023 Osteoporosis （OP） is a systemic bone disease and a common orthopedic disorder in elderly patients. High morbidity， disability and mortality rates and medical cost of OP bring huge burden to the patients and their family.
Zhang Wenhao, Yi Lin, Xiang Wenyuan, Remira·Aimaiti, Deng Yingjie, Liao Jun, Liang Zhiquan, Li Leijiang, Fang Rui
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Study of the effect of Strong-bone granules on the differentiation of ROS1728 osteoblasts with silenced ER expression [PDF]
, 2017 目的探讨健骨颗粒对成骨细胞中ERalpha介导的TERT信号通路的调控作用。方法采用雌激素受体拮抗剂ICI182780(Faslodex)阻断成; 骨细胞中雌激素受体alpha(ERalpha)的表达,建立ER抑制的大鼠成骨细胞株ROS1728细胞模型,采用酶联免疫吸附法(ELISA)检测成; 骨细胞液中碱性磷酸酶(alkaline phosphatase,ALP) 、骨钙素(osteocalcin,BGP); 、Ⅰ型胶原(collagen I,Col Ⅰ)的含量。采用实时荧光定量SYBR ...
吴银生 +6 more
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Research progress in the roles of Notch signaling pathway during fracture healing [PDF]
, 2023 Fracture is the most common large-organ injury in humans. It takes several months or even longer from the onset to the completion of bone reconstruction. In severe cases, delayed healing or even bone discontinuity can occur.
GUO Liqiang, SHU Bing, ZHAO Shitian
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miR-4319通过靶向TNFAIP3调控强直性脊柱炎成纤维细胞成骨分化
Zhongguo shiyan zhenduanxue, 2021 目的 探讨miR-4319对强直性脊柱炎（AS）成纤维细胞骨向分化的影响机制。方法 原代分离培养AS成纤维细胞和正常成纤维细胞;脂质体法将pcDNA组（转染pcDNA）、pcDNA-肿瘤坏死因子-α诱导蛋白3（TNFAIP3）组（转染pcDNA-TNFAIP3）、miR-NC组（转染miR-NC）、miR-4319组（转染miR-4319mimics）、miR-4319+pcDNA组（共转染miR-4319 mimics和pcDNA）、miR-4319+pcDNA-TNFAIP3组（共转染miR ...
周华朝, 张武
doaj
Effects of olive oil on osteoporosis after artificial menopause [PDF]
, 2015 随着妇科恶性肿瘤发病率的逐年上升及越趋年轻化，给社会和家庭带来了巨大的经济和精神负担。妇科恶性肿瘤主要以手术为主，并辅以放化疗。随着手术切除双侧卵巢及放化疗对卵巢损害的发生，将会导致雌激素急剧下降，从而增加骨质疏松症的发病率。目前激素替代疗法（hormonereplacementtherapy，HRT）广泛用于防治人工绝经后骨质疏松症，但是有临床大样本研究表明，HRT虽然能够减缓绝经后骨质疏松症的发生，但也增加了心血管疾病、乳腺癌、中风、糖尿病、宫颈癌、子宫内膜癌、卵巢癌等的发病率 ...
刘慧兰
core
Rare Metals, EarlyView.ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
Chemical Composition of Chinese Pyrola Herb Volatile and the Effects on the Osteoblast Proliferation [PDF]
, 2016 目的分析鹿衔草挥发油的化学成分,研究其对体外培养成骨细胞增殖的影响。方法采用水蒸气蒸馏法提取鹿衔草挥发油,GC-MS检测化学成分;鹿衔草挥发油干预成骨细胞系ROS17/2.8后,采用MTT法检测成骨细胞增殖,流式细胞术检测成骨细胞增殖周期,实时荧光定量PCR检测成骨细胞PCNA mRNA表达。结果一定浓度的鹿衔草挥发油能促进成体外培养成骨细胞增殖,处于增殖周期的成骨细胞比例明显增加,且成骨细胞的增殖细胞核抗原(Proliferating Cell Nuclear Antigen,PCNA ...
叶蕻芝 +6 more
core
Pharmacological Research Progress of Cistanches Herba [PDF]
, 2017 目的探讨肉苁蓉药理作用。方法收集近几年国内外对肉苁蓉药理作用的研究资料,并对其进行综述。结果现代药理研究表明,肉苁蓉有润肠通便、保肝、抗骨质疏松、抗氧化、抗衰老、抗疲劳等作用。结论肉苁蓉药理作用广泛,为其临床应用提供一定的参考依据。Objective Discuss deeply the pharmacological action of cistanches herba.
方鉴
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Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source