Results 141 to 150 of about 311,294 (224)

基于分子对接和QSAR方法预测B-Raf II型抑制剂活性

, 2015
刘海春, 卢帅, 冉挺, 张艳敏, 徐金星, 熊潇, 徐安阳, 陆涛, 陈亚东   +8 more
semanticscholar   +1 more source

In vivo study on IL-37 inhibition of malignant melanoma metastasis. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Yang J, Fu L, Yang Y, Lin L.
europepmc   +1 more source

两面针碱对钙调蛋白依赖环核苷酸磷酸二酯酶的抑制作用

Zhongshan Daxue xuebao. Yixue kexue ban, 1995
以钙调蛋白依赖环核苷酸磷酸二酯酶（ＣａＭ－ＰＤＥ）为分子模型，应用正文试验证实两面针碱（Ｎｉ－ｔｉｄｉｎｅ，Ｎｉｔ）是一种新的ＣａＭ拮抗剂。实验结果表明：①：Ｎｉｔ抑制ＣａＭ－ＰＤＥ活性ＩＣ５０为８６μｍｏｌ／Ｌ。②７５μｍｏｌ／ＬＮｉｔ对０～８０ｎｇ／ｍｌＣａＭ存在下，ＣａＭ－ＰＤＥＶｍａｘ基本不变，半激活浓度（ＡＣ５０）增大，抑制常数（Ｋｉ）为６６μｍｏｌ／Ｌ。提示Ｎｉｔ以竞争方式拮抗ＣａＭ对其靶酶（ＰＤＥ）的活化。③７５μｍｏｌ／ＬＮｉｔ对ＣａＭ－ＰＤＥ抑制动力学研究：改变底物（ｃＡＭＦ）浓度 ...
doaj  

[Inhibition of ferroptosis alleviates acute kidney injury caused by diquat in zebrafish]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Ou Z, Li Y, Chen S, Wang Z, He M, Chen Z, Tang S, Meng X, Wang Z.   +8 more
europepmc   +1 more source

[Antitumor component-Ι in <i>Agkistrodon halys</i> venom inhibits proliferation and migration of cisplatin-resistant gastric cancer cells by downregulating RAI14]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li Y, Li CDC, Guo R, Han H, Lu L, Zhou F, Zhi H, 支 慧.   +7 more
europepmc   +1 more source

[Design, Synthesis, and Efficacy Evaluation of a Novel BRD4/HDAC Dual-Target Small-Molecule Inhibitor in Prostate Cancer]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Feng S, Shao Y, Wu K, Yang W, Li X.
europepmc   +1 more source

[Acquired factor ⅩⅢ deficiency with FⅩⅢ inhibitor secondary to rheumatoid arthritis: a case report]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhu BC, Cai HC, Zhang Y, Wang L, Wang W.
europepmc   +1 more source

[Inhibitory Effects of the Deep Underground Low Background Radiation Environment on the Proliferation and Migration of NP69 Human Nasopharyngeal Epithelial Cells and the Underlying Mechanisms]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Hao Z, Li C, Wang L, Zou Y, Wen J, Wu J, Wan X, Liu F, Liu J.   +8 more
europepmc   +1 more source

[Research progress on targeted delivery of proteasome inhibitor nanoparticles for the treatment of multiple myeloma]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Lin YX, Jing DH, Mi JQ.
europepmc   +1 more source

Classical Eyelid Conditioning and Personality Factors [PDF]

, 1979
Hiraoka Kiyoshi, 平岡 清志
core   +1 more source