本发明涉及抑制血管紧张素转换酶(angiotensin-converting?enzyme,ACE)活性及降血压的四种多肽化合物ATVLNYLP,ACEPGVDYVY,VTSIDWVR,SSEANLYR,它们的氨基酸序列分别为Ala-Thr-Val-Leu-Asn-Tyr-Leu-Pro,Ala-Cys-Glu-Pro-Gly-Val-Asp-Tyr-Val-Tyr,Val-Thr-Ser-Ile-Asp-Trp-Val-Arg,Ser-Ser-Glu-Ala-Asn-Leu-Tyr-Arg ...
靳艳, 邹汉法, 刘晓艳
core
[Preliminary investigation into the mechanisms of thalidomide in inhibiting the malignant transformation of oral leukoplakia]. [PDF]
Shang Q, Awuti G, Xu H, Chen Q, Zhao J.
europepmc +1 more source
[Dihydroartemisinin inhibits the progression of oral squamous cell carcinoma]. [PDF]
Shan T +5 more
europepmc +1 more source
[Tongdu Zhiyu Acupuncture Improves Post-Stroke Depression by Upregulating miR-223-3p and Inhibiting NLRP3 Inflammasome: A Clinical Study]. [PDF]
Zhang J +7 more
europepmc +1 more source
[Dual inhibition of PSME2 and STAT3 induces ferroptosis in esophageal squamous cell carcinoma cells by regulating the SLC7A11/GPX4 axis]. [PDF]
Qi C +7 more
europepmc +1 more source
[Multiple components in Astragalus Injection target CCL2/FOS/PPARG/CXCL8 to suppress cervical cancer progression]. [PDF]
Ma Y +10 more
europepmc +1 more source
分析了微型激光投影引擎的两种主要光学噪音:干涉网格和激光 散斑产生的基理;提出采用振动的随机位相板同时实现干涉网格和激光散斑抑制的方法并进行了理论分析;自行设计了微型激光投影引擎,利用微型电控马达带动随 机位相板振动,用CCD相机在不同的F#及曝光时间下对投影图像进行了采集,并对图像的散斑对比度行了测试.结果表明,通过静止的随机位相板可以很好地抑 制干涉网格噪音;通过使随机位相板以大于视觉暂留效应形成的融合频率进行振动,可以同时抑制干涉网格和激光散斑,使得散斑对比度小于5%,达到投影观察的 要求.
庄松林, 杨波, 张薇
core
【目的】 探讨去甲二氢愈创木酸对骨肉瘤细胞Mg63的生长抑制作用及其机制. 【方法】 应用四甲基偶氮唑蓝(MTT法)和克隆形成法测定去甲二氢愈创木酸对Mg63细胞的生长抑制作用,检测其抑制骨肉瘤细胞生长的时间效应和剂量效应;用流式细胞技术进行细胞周期分析;用Western blot法检测药物对Mg63细胞mTORC1信号通路活性的影响.【结果】 去甲二氢愈创木酸对Mg63细胞具有明显的生长抑制作用,且呈时间依赖和剂量依赖关系,72 h IC50值为(48 ± 2)μmol/L?10?20?50 ...
doaj
[Anwulignan inhibits malignant phenotypes of gastric cancer cells by antagonizing activation of the JAK1/STAT3 signaling pathway]. [PDF]
Liu X +9 more
europepmc +1 more source
[Mechanism and clinical progress of JAK inhibitors in hemophagocytic lymphohistiocytosis]. [PDF]
Wang MX +4 more
europepmc +1 more source

