Results 21 to 30 of about 664,468 (171)

Dual‐Regulation of Continuous and Discontinuous Precipitation via Carbon Alloying for Enhanced Strength‐Ductility Synergy in a Medium‐Entropy Alloy

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT The exceptional ductility of face‐centered cubic high/medium‐entropy alloys (H/MEAs) is counterbalanced by intrinsically restrained yield strength, fundamentally compromising their application in structural and functional materials. Here, a novel carbon (C)‐driven precipitation strategy is introduced to promote discontinuous precipitation (DP)
Hao Feng   +10 more
wiley   +1 more source

抑制机制研究的新进展

open access: yes, 1999
在近几年的一些认知研究中, 抑制机制作为认知活动的一个重要维度开始受到越来越多的重视 ...
杨丽霞, 陈永明
core   +1 more source

瞬时受体电位M2型通道抑制剂的开发现状

open access: yes浙江大学学报. 医学版
开发高效且特异的瞬时受体电位M2型(TRPM2)通道抑制剂,不仅有助于深化对相关疾病病理机制的理解,还能为临床治疗提供新的有效靶点和候选药物。根据研发方法不同,TRPM2通道抑制剂的开发主要分为四类,分别有以下特点:同源离子通道调节剂的再利用及结构改造能够发现多种抑制效果较强的TRPM2通道抑制剂;基于通道开放机制开发所得的TRPM2通道抑制剂通常表现出良好的选择特异性;高通量筛选开发所得的抑制剂往往具备新颖的化学结构,丰富了TRPM2通道抑制剂的设计思路;开发源于天然抗氧化剂的抑制剂则具备较高安全性 ...
陈 世尧   +4 more
doaj   +1 more source

Hierarchically Structured Zn‐ZnO@HA/PCL Biocompatible Coating: Enabling Controlled Degradation and Mechanical Stability of Magnesium Alloy Bone Implants

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Biodegradable magnesium alloys are limited in orthopedic applications due to their rapid corrosion and poor interfacial stability. In this work, a composite coating is constructed via magnetic filtered cathodic vacuum arc (MFCVA) deposition of a Zn interlayer, followed by hydrothermal in situ generation of ZnO to induce hydroxyapatite (HA ...
Chao Zhang   +9 more
wiley   +1 more source

蛋白质磷酸化酶抑制剂对肺癌细胞株的增殖抑制作用 附视频

open access: yesZhongguo shiyan zhenduanxue, 1998
目的探讨蛋白质磷酸化酶抑制剂对肺癌细胞株的增殖抑制作用。方法用蛋白质磷酸化酶抑制剂对6株小细胞肺癌和7株非小细胞肺癌细胞株的增殖抑制效果进行了检测,并采用免疫法,测定了蛋白质磷酸化酶抑制剂对肺癌细胞内Rb蛋白表达的影响。结果随其浓度的增加,对肺癌细胞株的增殖抑制作用增强,小细胞肺癌的半数抑制量平均值ST为95nM,UCN-01为588nM,非小细胞肺癌则分别为188nM和1029nM,ST和UCN-01可抑制肺癌细胞Rb蛋白的磷酸化。结论蛋白质磷酸化酶抑制剂通过抑制Rb蛋白的磷酸化 ...
赵美蓉, 王杨, 裴瑞莲
doaj  

GHK‐Cu Delays Aging Through the Repair of Mitochondrial Dysfunction

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Althugh glycyl‐L‐histidyl‐L‐lysine copper (GHK‐Cu) shows antiaging potential, its precise molecular mechanisms remain unclear. Using Caenorhabditis elegans (C. elegans) as an in vivo aging model, we observed that GHK‐Cu extended organismal lifespan and improved stress resilience.
Haoquan Yu   +8 more
wiley   +1 more source

Synergistic Enhancement of Creep Performance in Al19Co21Fe20Ni40 Eutectic High‐Entropy Alloy by Coupling Heterostructure Design With Boron‐Assisted Interfacial Optimization

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT This study systematically investigates the creep behavior of an Al19Co21Fe20Ni40 eutectic high‐entropy alloy (EHEA) at 500°C, focusing on the synergistic effects of heterostructure design and trace boron doping. Thermomechanical processing was employed to produce a heterostructure consisting of alternating lamellar and equiaxed regions.
Xudong Liu   +7 more
wiley   +1 more source

Ultrasonic Spray Pyrolysis‐Derived LSCF‐GDC Nanocomposites as Durable Oxygen Electrodes for Solid Oxide Electrolysis Cells

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Solid oxide electrolysis cell (SOEC) technology is a promising route for efficient and clean green hydrogen production because of its high conversion efficiency and the use of precious‐metal‐free catalysts. However, developing oxygen electrodes that combine high electrochemical activity with robust long‐term operational stability remains ...
Yue Zhao   +8 more
wiley   +1 more source

Sb2S3 Nanorods Anchored on Lignite‐Derived Carbon With Strong C‐S Interfacial Coupling Enabling High Initial Coulombic Efficiency Sodium‐Ion Batteries

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Sb2S3 is regarded as a promising anode for sodium‐ion batteries (SIBs) because of its high theoretical capacity and moderate working potential. However, it suffers from huge volume changes, poor conductivity, and excessive side reactions, leading to severe capacity decay and a low initial Coulombic efficiency (ICE), thus limiting its practical
Jia‐Hao Zhao   +6 more
wiley   +1 more source

小叶女贞叶片脲酶抑制物质的提取及抑制作用研究

open access: yes四川大学学报. 自然科学版, 2010
从小叶女贞叶片中提取分离了具有抑制脲酶作用的活性成分并对其抑制作用进行研究.结果显示该活性物质主要成分为多糖和酚类物质,对脲酶有较强的抑制作用,随着脲酶抑制物质浓度增加,抑制作用增强.加入β-巯基乙醇(2-Me)后,脲酶的活性恢复,说明该脲酶抑制物质是通过与脲酶的-SH发生作用而导致脲酶的活性降低.
武慧玲, 王胜华, 陈放
doaj  

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