Results 51 to 60 of about 311,294 (224)

Deapartment of Pathogenic Biochemistry [PDF]

open access: yes, 2002
I.癌および癌転移の抑止に関する基礎的研究1)癌および癌転移の抑制物質の探索(伝統薬物を中心に)2)癌の悪性化・進展モデルの確立とその分子機序の解析3)癌ワクチンを指向した免疫遺伝療法の開発と免疫力増強物質の検索4)同所移植性転移モデルにおける転移の臓器特異(選択)性とその機序の解析5)細胞接着の制御に基づく浸潤・転移の抑制6)基底膜分解酵素の転写・産生・分解レベルでの阻害物質の探索II.免疫抑制に関する基礎的研究1)アレルギー性/炎症性疾患モデルの確立と有効物質(抑制/増強)の探索2 ...
中島 松一   +4 more
core   +1 more source

On the Damage Tolerance of Diffusion Bonded Titanium–Aluminum Phase Biomimetic Composites

open access: yesRare Metals, EarlyView.
ABSTRACT The biomimetic design principles of natural structures involve the strategic integration of stiff and compliant phases to synergistically enhance strength and toughness. Its evolutionary refined natural armor, characterized by a specialized microarchitecture, enables superior damage tolerance.
Shuai Tong   +10 more
wiley   +1 more source

Using porous metals to enhance heat transfer in phase change materials (PCMs) [PDF]

open access: yes, 2011
Heat transfer enhancement mechanism of Phase Change Materials (PCMs) by high-porosity metal foams was investigated in this study. The Darcy-Brinkman-Forchheimer modified flow model was employed in the numerical simulations to consider the non-Darcy ...
Tian, Y. (Yuan), Zhao, Changying
core  

Engineering a Tumor‐Targeted MgH2@Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

open access: yesRare Metals, EarlyView.
ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu   +5 more
wiley   +1 more source

铜绿假单胞菌对假丝酵母菌的影响

open access: yesZhongguo shiyan zhenduanxue, 2015
目的研究临床分离的铜绿假单胞菌(PA)对常见假丝酵母菌(包括白色假丝酵母菌、热带假丝酵母菌、光滑假丝酵母菌、近平滑假丝酵母菌、克柔假丝酵母菌和葡萄牙假丝酵母菌等)的抑制作用。方法通过革兰染色、菌落形态、氧化酶试验及上机鉴定收集临床上120株PA;通过纸片法检测PA对常见假丝酵母菌的抑制作用,根据对假丝酵母菌有无抑制作用将PA分为抑制性PA和非抑制性PA;利用十二烷基硫酸钠‐聚丙烯酰胺凝胶法(SDS‐PAGE)对两组PA进行分泌蛋白电泳,观察电泳条带的差异 ...
孙安民, 王伟
doaj  

The toxicity of Rapamycin derivatives—Everolimus, Deforolimus, Zotarolimus on islet [PDF]

open access: yes, 2016
目的:免疫抑制剂的开发与运用一直推动着器官移植领域的发展。自21世纪初,Edmonto方案被提出以后,胰岛移植领域发生的了质的飞跃,尤其是雷帕霉素与他克莫司的开发与利用,使得该方案得到广泛的认可与临床运用。然而随着研究的不断深入,研究者们发现免疫抑制剂在延长移植物存活时间的同时,也给胰岛本身带来了严重的毒性作用,包括抑制胰岛细胞增殖,促进胰岛细胞凋亡,抑制胰岛细胞分泌胰岛素等。应用免疫抑制剂产生的这些不良反应在抗器官移植排斥反应时发生。它们作为抗肿瘤药物应用于临床时也会诱发高血糖的现象。所以 ...
张娟
core  

気管支喘息患者における白血球ロイコトリエン産生能に対する不飽和脂肪酸食の効果に影響する因子 [PDF]

open access: yes, 1999
Dietary supplementation with perilla seed oil, a vegetable oil rich in α -lin- olenic acid, inhibits the generation of leukotrienes(LTs) by leucocytes in patients with bronchial asthma. We examined the factors that affect the suppression of LT generation
Ashida, Kozo   +11 more
core   +1 more source

A Multifunctional Reducing Molecular Dopant for 16% Efficient Tin Perovskite Solar Cells

open access: yesRare Metals, EarlyView.
ABSTRACT Although lead‐based photovoltaics have seen remarkable progress, tin‐based perovskite solar cells (Sn‐PSCs) continue to face challenges due to their limited power conversion efficiency and insufficient operational stability. The primary cause of this performance gap is the susceptibility of Sn2+ to oxidation, which promotes rapid defect ...
Xianyong Zhou   +12 more
wiley   +1 more source

智能电器监控单元浪涌抑制网络工作状态分析和改进

open access: yesGaoya dianqi, 2007
将由电源滤波器、压敏电阻、瞬态电压抑制器(TVS)组成的串级浪涌抑制网络应用于智能电器监控单元电源端口,通过试验观察到该网络的残压水平过高,对后级电路存在着潜在的危险,采用波过程理论对这一现象进行分析,发现开关电源阻抗变化会影响到串级浪涌抑制网络的配合。对抑制网络的结构进行了改进,通过试验可以证明改进后的抑制网络能够明显提高对浪涌过电压的抑制效果。
牛博   +4 more
doaj  

"fordi før så skreiv æ Å-G". En studie om andreklassingers valg av stavemåter.

open access: yes, 2023
The purpose of this master's thesis has been to look at the choices students in Year 2 make when spelling words. The students participating in this research are in the transition between phonological and orthographic writing, and the study will focus on how these students adopt different spelling strategies. The assignment's data material is taken from
openaire   +1 more source

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