Zhongshan Daxue xuebao. Yixue kexue ban, 1989 用人新鲜胰腺癌组织免疫BALB/c小鼠,取脾细胞与小鼠骨髓瘤细胞Sp2/0-Agl4融合,获得了分泌抗人胰腺癌单克隆抗体的杂交瘤细胞株。本文重点报道以ABC免疫组织化学法检查YPC1单克隆抗体与人正常组织和肿瘤组织的反应性。结果表明YPC1单克隆抗体与16例被检测的胰腺癌组织发生反应。其中9例(56.3％)呈强阳性反应,与23种正常组织中的10种(43.5％)以及19种非胰腺肿瘤中的8种(42.1％)有不同程度的交叉反应,但多数反应较弱。本研究提示以新鲜人体肿瘤组织作为免疫原制备单克隆抗体是简便可行的 ...
doaj
, 2007 目的:观察藤梨根和益气补肾口服液对S180实体瘤的抑制作用,并进行病理学观察。方法:用小鼠S180模型,观察藤梨根和益气补肾口服液对肿瘤的抑制作用,计算抑瘤率,并做病理学检查。结果:藤梨根和益气补肾口服液高、中、低剂量组与模型组比较,对S180实体瘤均有一定的抑制作用,但益气补肾口服液抑瘤率较藤梨根高。结论:藤梨根有一定的抑制S180生长的作用 ...
郭建友, 阮叶萍
core
[Single extract of Forsythia Suspense versus the prepared drug in pieces: comparison of their anti-inflammatory, antitumor and antibacterial effects in zebrafish]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoGuo X +8 more
europepmc +1 more source
, 2008 目的对海洋弧菌B2817的抗肿瘤活性成分进行分离纯化和结构鉴定。方法采用溶剡萃取、制备HPLC等分离手段，对该菌株所产的活性成分进行了活性追踪分离，通过现代波谱学手段进行化学结构鉴定，以MTT法评价了化合物的抗肿瘤活性。结果从中分离得到4个化合物，分别鉴定为灵菌红素（1）、肉豆蔻酸（2）、7-十六碳烯酸（3）、7，10-十八碳二烯酸（4）。化合物1对肿瘤细胞SM7721、S180具有强细胞毒活性，IC50分别为6．3、5．6μg·mL^-1，而对人正常肝细胞HL—02无毒性 ...
肖红斌 +6 more
core
[ORY-1001 inhibits glioblastoma cell growth by downregulating the Notch/HES1 pathway via suppressing lysine-specific demethylase 1 expression]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYang H, Xiang Y, Tan T, Lei Y.
europepmc +1 more source
[Efficacy of CD4/TGF-β bispecific antibody in a mouse model of peritoneal metastasis of malignant melanoma]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoJiang Q +11 more
europepmc +1 more source
[Bone marrow infiltration of large B-cell lymphoma with clinical manifestations similar to systemic lupus erythematosus: A case report]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanMa D +5 more
europepmc +1 more source
[Molecular mechanisms and clinical applications of anti-angiogenic therapy in precision treatment of breast cancer]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanWang H, Jiang Y.
europepmc +1 more source
[Incidence of severe cancer therapy-related thrombocytopenia and associated factors in children]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiChen L +5 more
europepmc +1 more source
[Conversion therapy for hepatoid adenocarcinoma of the stomach: A case report]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanLi J, Chen L, Tang J, Wu Y, Wang A.
europepmc +1 more source