[<i>Tianma Gouteng</i> Granule improves motor deficits in mouse models of Parkinson's disease by regulating the necroptosis pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoChen D +7 more
europepmc +1 more source
Jianzhu Gangjiegou Jinzhan为系统研究梁柱采用自复位连接组合框架的抗震机理，选取预拉杆长度设置、PEC柱截面强弱轴布置和柱脚连接方式3个设计参数，设计制作了4榀PEC柱-钢梁梁柱摩擦耗能部分自复位连接组合框架1∶2缩尺试件并进行拟静力抗震试验。通过试验现象观察和数据分析，对试件的滞回特性、抗侧刚度退化、复位能力、滞回耗能等抗震性能进行研究。结果表明：摩擦耗能部分自复位连接通过T形件长圆孔合理设置实现了“设计地震水平阶段实现复位，大震设计水平阶段自复位连接连接转化为伴随出现螺栓承压型受力实现部分自复位”的性能化设计目标；设计地震阶段，
方有珍 +4 more
doaj
[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhao B +8 more
europepmc +1 more source
[Sulforaphane reduces reactive astrocyte-mediated neuron apoptosis <i>in vitro</i> by inhibiting the MAPK/NF-κB signaling pathway in Aβ42 oligomer-activated astrocytes]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang S +5 more
europepmc +1 more source
Jianzhu Gangjiegou Jinzhan利用ABAQUS软件对14个T形PEC柱进行低周反复加载模拟，分析不同参数对T形PEC柱抗震性能的影响规律。结果表明：T形PEC柱的滞回曲线呈饱满的平行四边形，且刚度退化稳定，耗能能力和延性良好；提高混凝土强度等级虽然可增大柱的初始刚度，但混凝土强度等级过高则会导致柱的延性降低，刚度退化加剧，抗震性能降低；在T形PEC柱内设置横向拉杆，且将x方向和z方向的横向拉杆相互焊接，有利于对混凝土形成套箍作用从而提高柱的抗震性能，但拉杆间距不宜大于150 mm ...
李媛萍, 刘谋雷
doaj
[A neural circuit from paraventricular hypothalamic nucleus oxytocin neurons to trigeminal nucleus caudalis GABAergic neurons modulates pain sensitization in a mouse model of chronic migraine]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanChen H, Zou W, Xu X, Bian J.
europepmc +1 more source
特高压换流站气体绝缘金属封闭输电线路（GIL）抗震性能提升方法研究
Gaoya dianqi随着气体绝缘金属封闭输电线路（GIL）在特高压换流电站中的广泛应用，地震对其结构安全的影响备受关注。文中基于精细化有限元模型，分析了GIL在地震作用下的响应特征，并针对抗震薄弱点提出了针对性的性能提升方法。研究表明，GIL的主要薄弱点位于竖向转角处，存在外壳强度破坏和内部导体接头拔出破坏两种模式。此外，支架的动力放大效应显著，加速度放大系数通常超过2.0，但支架的动力放大作用并非唯一决定GIL抗震性能的因素。通过提高支架的基频和固定支架与外壳的连接方式，能够有效降低内部导体的相对位移峰值和外壳的应力峰值，
王电处, 余荣兴, 李浩丹, 张涵
doaj
[Pinostrobin targets the PI3K/AKT/CCL<sub>2</sub> axis in intestinal epithelial cells to inhibit intestinal macrophage infiltration and alleviate dextran sulfate sodium-induced colitis in mice]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang K +7 more
europepmc +1 more source
[Molecular Mechanisms of Intervention With Lishukang Capsule in a Rat Model of High-Altitude Pulmonary Edema]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZhang D +5 more
europepmc +1 more source
[Untargeted metabolomics reveals differential serum metabolites and metabolic pathways in patients with primary Sjögren syndrome and thrombocytopenia]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanXiang Z, Yang L, Yang J.
europepmc +1 more source