抗リン脂質抗体症候群は,抗カルジオリピン抗体やループスアンチコアグラントなどに代表される抗リン脂質抗体(aPL)の出現と,それに伴う動脈・静脈血栓症や習慣性流死産を特徴とする自己免疫性血栓性疾患であるが,その発症機序は未だ解明されていない.我々は,aPLがリン脂質に直接結合する抗体ではなく種々のタンパク分子が酸性リン脂質に結合し構造変化を起こした際に出現する新たなエピトープを認識して結合する抗体であることに着目し,5種類のリン脂質結合タンパク[β2-グリコプロテインI(β2-GPI),プロトロンビン ...
野島, 順三
core
[Clinical characteristics of children with anti-neutrophil cytoplasmic antibody-associated vasculitis]. [PDF]
Liu JQ +9 more
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[Two Cases of Behcet's Disease-Like Syndrome with Gene Deficiency in ELF4]. [PDF]
Wang N, Xie Y, Wang Z.
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[Biological characteristics and translational research of dental stem cells]. [PDF]
Ou Q +6 more
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[Recent advances of molecular imprinting technology for the separation and recognition of complex biological sample systems]. [PDF]
Xie BX, Lyu Y, Liu Z.
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[Research progress on the role of adipokines in intervertebral disc degeneration]. [PDF]
Gong C, Zhao G, Xiang G, Liu K, Zhang H.
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[Screening for Characteristic Genes of Different Traditional Chinese Medicine Syndromes of Psoriasis Vulgaris: A Study Based on Bioinformatics and Machine Learning]. [PDF]
Liu X +6 more
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[Progress on the roles of glia in postoperative cognitive dysfunction]. [PDF]
Niu W, Li Q, Jiang R.
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[Clinicopathological significance and prognostic value of serum 25-hydroxyvitamin D3 level in children with IgA vasculitis nephritis]. [PDF]
Yu P +6 more
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[PLCE1 mutation-induced end-stage renal disease presenting with massive proteinuria: a family analysis and literature review]. [PDF]
Abasi R +5 more
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