Results 21 to 30 of about 63,434 (198)
Structural Probability Damage Identification with Integration of Structural Reliability Evaluation [PDF]
, 2016 考虑不确定性的损伤识别及可靠度指标对结构安全评估起着关键作用。由于各种不确定性因素的影响，从而导致观测数据、识别结果具有不确定性问题。目前，关于损伤识别的理论和方法有很多，然而基于不确定性的损伤识别及可靠度研究仍是一个重要课题。 常用的不确定性的结构损伤识别方法主要分为以下几类：1）基于经典概率统计的损伤识别；基于概率的损伤识别方法都是采用数值仿真算例来进行的，对于损伤和噪声的模拟同实际结构会有一定的出入。2）基于贝叶斯模型修正的损伤识别；贝叶斯模型修正方法大多是将预测误差建模为高斯白噪声过程 ...
翁梦秀
core
On the Damage Tolerance of Diffusion Bonded Titanium–Aluminum Phase Biomimetic Composites
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT The biomimetic design principles of natural structures involve the strategic integration of stiff and compliant phases to synergistically enhance strength and toughness. Its evolutionary refined natural armor, characterized by a specialized microarchitecture, enables superior damage tolerance.
Shuai Tong +10 more
wiley +1 more source
The role of jumping translocation breakpoint gene promoting instability of genome and the biological function of its protein and potential clinical value [PDF]
, 2014 染色体不稳定性是大多数肿瘤细胞特别是实体瘤细胞和体外转化细胞的基本特征。其表现形式包括整条染色体的获得或缺失，杂合缺失，染色体易位重排，基因扩增等。目前认为染色体不稳定是肿瘤形成的始发因素，出现在肿瘤进展的早期阶段。体内外各种损伤刺激导致的基因组DNA链的断裂是染色体不稳定的根本原因。我们的研究发现，跳跃易位断裂点基因（JTB）在胃癌、肝癌中存在广泛的基因扩增和基因易位行为，而基因的扩增和易位是DNA双链断裂后异常修复的最终结果。JTB基因的断裂易位将导致其编码跨膜结构域的基因序列丢失 ...
刘贇鹏
core
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT TA18 alloy is an ideal material for piping systems in the aerospace field, the low notch sensitivity and high damage tolerance enhance its engineering application value. However, the complex failure mechanism influenced by strain gradient necessitates further improvement of the service stability for TA18 alloy in practical engineering ...
Xin Du +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2020 骨骺损伤是青少年时期特有的损伤,而胫骨近端骨骺损伤则是一种少见的特殊类型的骺损伤[1],通常以单侧为主,多为运动损伤所致。治疗方案根据损伤类型、复位质量及骨折块复位后的稳定性决定保守治疗或手术治疗[2-4,8,9]。2019年初我科收治了一例Ⅱ型胫骨近端骨骺损伤患者,现将该患者的临床资料报告如下:
窦世鲁 +4 more
doaj
Asparagus Oligosaccharide’s Purification and Protection of Acute Alcoholic Liver Injury in Kunming Mice [PDF]
, 2015 寡糖具有抗病毒、抗肿瘤、抗氧化、免疫调节等生物活性，是一种高活性物质，在医药和功能性食品领域显示了巨大的应用前景。与其它来源于植物、几丁质的寡糖相比，目前来源于海藻的寡糖尚未得到大规模开发。本研究前期工作中建立了利用微生物与龙须菜（Gracikarialemaneifarmis）共培养，一步法获得寡糖的方法，简化了生产步骤，降低了成本，并开展了龙须菜寡糖的各项活性研究与开发。本文研究了龙须菜寡糖的纯化方法，并研究其在动物生长、急性酒精肝损伤保护等方面的生理活性。 首先对龙须菜寡糖的纯化制备进行研究 ...
刘海凤
core
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 脑损伤是外界暴力作用于头部造成的脑组织器质性损伤,脑损伤包括脑震荡、弥漫轴索损伤、脑挫裂伤和脑干损伤。急性脑损伤往往表现为发病急,病情变化快,病情危重,致残率和病死率高[1,2]。脑损伤根据伤后脑组织与外界相通与否分为开放性或闭合性脑损伤。脑震荡头部CT检查无异常;脑挫裂伤头部CT了解有无骨折、蛛网膜下腔出血、有无颅内血肿。头部MRI了解具体损伤部位、
方思月, 杨涟
doaj
The mechanism of BaP and DDT co-exposure induced DNA damage via MAPK signal pathway [PDF]
, 2016 【目的】 苯并(a)芘(benzo[a]pyrene，BaP)是多环芳烃类化合物的典型代表之一，于各种环境介质中广泛存在，具有很强的致癌性，被国际癌症研究机构列为1类致癌物。滴滴涕(2，2-bis(4-chlorophenyl)-1，1，1-trichloroethane，DDT)曾是生产及使用范围最广的一类有机氯农药，在环境中非常难于降解，具有高亲脂性，可以对哺乳动物的肝脏、肾脏、神经等系统造成损害。BaP和DDT常共存于环境并可通过食物链的生物放大作用富集于人体，危害人类健康。因此 ...
刘敏
core
Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu +12 more
wiley +1 more source