Results 21 to 30 of about 25,148 (152)

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu   +12 more
wiley   +1 more source

28例颅脑外伤合并视神经损伤的诊治分析

open access: yesZhongguo shiyan zhenduanxue, 2011
视神经损伤是在颅脑损伤中虽不多见但较为严重的并发症之一,手术治疗效果较好。闭合性颅脑损伤合并视神经损伤患者多数为单侧视神经损伤,发病率约为0.5%-4.0%[1],损伤程度较轻者可出现视力下降,视神经萎缩 ...
黄锐, 关文明, 吴艳英
doaj  

Test and Research on the Rheological Damage Properties of Sandstone under Dynamic stress field-Seepage field coupling [PDF]

open access: yes, 2016
机械振动、交通荷载、地震等产生的动应力场与降雨等因素所产生的渗流场耦合,会加快软岩的流变损伤,导致滑坡、崩塌、泥石流等严重的地质灾害。因此,加强对动应力场-渗流场耦合作用下软弱岩体的动态流变损伤特性的研究具有重要的理论和实际意义。论文以软弱砂岩为研究对象,利用重庆大学煤炭灾害与控制国家重点实验室的RLW-2000M煤岩三轴流变试验机研究了砂岩在动应力场-渗流场耦合作用下的动态流变损伤特性。具体的研究内容如下: (1)通过采集-钻芯-切割-打磨-浸泡等过程制备饱和的砂岩试样,根据砂岩试样的全应力 ...
蔡亮
core  

Optimal Laser Strike Intensity to Realize “Nonlethal Pain Stimulation Deterrence” in Human‐Wildlife Conflict Management: Wild Boar as a Case Study 人兽冲突管理中 “非致命性痛觉刺激驱离技术” 的最优激光打击强度 —— 以野猪为案例

open access: yesWildlife Letters, Volume 3, Issue 4, Page 194-202, December 2025.
This study establishes the optimal nonlethal laser deterrence range (210–260 W, 1s) for wild boars, preventing agricultural damage while ensuring animal safety. Results demonstrate that efficacy requires seasonal power adjustments (≤ 285 W in winter) and precise targeting control—enabling effective, injury‐free wildlife conflict mitigation.
Zhenyang Li   +6 more
wiley   +1 more source

Anatomic and radiograph study of anterior cruciate ligament reconstruction [PDF]

open access: yes, 2015
目的:1、观察膝关节交叉韧带股骨附着处的解剖形态学特点,并利用PhotoshopCC2014软件测量股骨附着处印迹的实际面积大小;2、研究标准膝关节侧位X线片上前交叉韧带(ACL)股骨止点的相关骨性标志数据,为临床上ACL双束解剖重建提供参考。 方法:对10例成人膝关节标本进行解剖,剔除膝关节标本周围肌肉、关节囊,把髌韧带从股骨端切断,保留髌骨、髌韧带、内外侧副韧带、前后交叉韧带及内外侧半月板,经髁间窝前出口最高点沿矢状面在股骨前面和后面作两条平行股骨纵轴的直线,用手锯沿两直线将股骨分为两部分 ...
甘志勇
core  

European Trauma Policy: A Systematic Review of European Union Institutions and Legislation Addressing Orthopedic Surgery and Traumatology During and After the COVID‐19 Pandemic

open access: yesWorld Medical &Health Policy, Volume 17, Issue 4, Page 775-790, December 2025.
ABSTRACT The COVID‐19 pandemic had a detrimental impact on healthcare provision globally and in the European Union (EU). This paper investigates european health policy oriented towards orthopedics and traumatology since the onset of the pandemic. A search of peer–reviewed literature and European Union legislation and scientific databases has been ...
Christos Tsagkaris   +3 more
wiley   +1 more source

基于小鼠脊髓背侧半切损伤模型的小胶质细胞激活情况的观察

open access: yesZhongguo shiyan zhenduanxue, 2018
脊髓损伤是一种中枢神经系统的严重创伤,常导致灾难性的神经功能障碍,治疗恢复手段十分有限,预后不佳。脊髓损伤的病理过程一般被分为原发性损伤和继发性损伤,原发性损伤主要与受伤原因和暴力严重程度有关,损伤过程主要发生在暴力发生的瞬间或是之后几秒内,所以干预的机会和手段十分有限[1]。继发性损伤是在原发性损伤因素的基础上发生局部出血,细胞坏死,细胞内酶类释放,
高忠文   +4 more
doaj  

Effects and mechanisms of Pd-Ia on LPS-induced acute lung injury in mice [PDF]

open access: yes, 2016
目的:随着环境的不断恶化,空气质量越来越差,并且已经严重影响到了人们的身体健康,雾霾已经遍布中国的众多城市,使得呼吸系统疾病的发病率日渐升高。急性肺损伤(ALI)/急性呼吸窘迫综合征(ARDS)都是比较常见的临床呼吸系统疾病,ARDS对于临床疾病来说,可谓是灾难性的,属于严重的呼吸衰竭,目前无有效的药物治疗措施。ALI是ARDS的早期阶段,其特点是弥漫性的炎症损伤,目前研究发现中药白花前胡根中提取出的活性成分白花前胡甲素(Pd-Ia)在LPS诱导的内皮细胞炎症损伤中具有良好的抗炎效果 ...
周晓霞
core  

Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 453-461, August 2025.
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos   +5 more
wiley   +1 more source

Function of SAV6 in Maintenance of Genome Integrity and Root Development in Arabidopsis [PDF]

open access: yes, 2015
flap核酸内切酶FEN1(flapendonuclease1)是RAD2家族的一种能够识别特异底物结构的核酶。FEN1具有三种酶活性:flap核酸内切酶(FlapEndonuclease,FEN)活性、5’核酸外切酶(5’-Exonuclease,EXO)活性和缺口依赖的核酸内切酶(GapEndonuclease,GEN)活性,在DNA复制、修复以及维持端粒稳定性等方面发挥着重要作用。人们对FEN1在哺乳动物、酵母中的功能已经有了深入了解,但是拟南芥中尚无相关研究 ...
张益娟
core  

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