Results 21 to 30 of about 13,461 (187)
Selective Isolation, Identification and Biological Activity Investigation of Rare Actinomycetes from Rhizosphere Soil [PDF]
, 2016 天然产物是新药制备的重要原料，绝大多数来源于微生物的天然产物都分离自放线菌，尤其是链霉菌。链霉菌是放线菌的重要组成成员，能合成结构类型丰富、生物活性多样的次级代谢产物，可用于创制抗生素、抗肿瘤药物、免疫抑制药物、抗虫药物等，在医疗、农业、食品等领域具有重要的应用价值。然而，随着对链霉菌持续的开发利用，目前从链霉菌中发现新型、高活性的次级代谢产物的几率在不断下降，来源于链霉菌的新药研发速度明显放缓。为了解决链霉菌活性次级代谢产物资源日趋枯竭的问题 ...
施金迪
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Weaving knowledges to support wildlife health surveillance in Kenya's pastoral rangelands
Conservation Biology, Volume 40, Issue 1, February 2026.Abstract In wildlife–livestock–human interfaces, pathogens capable of spreading between wild and domestic animals and humans have important implications for conservation outcomes, economics, and public health. Robust wildlife health surveillance can help address these risks.
Brock Bersaglio +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2004 目的 比较不同性别患者标本中支原体和衣原体分离率及对 6种抗菌素的耐药性。方法 采用IST和VI DAS试剂盒 ,对 4 5 5例疑为NGU患者的泌尿生殖道标本进行了支原体和衣原体检测 ,同时对支原体检测阳性标本进行了菌落计数和抗生素敏感性检测。结果 4 5 5例标本中支原体和衣原体分离率为 36 8% ,其中男性标本中支原体和衣原体分离率为 19 9% ,女性标本中支原体和衣原体分离率为 5 2 3%。Uu菌落计数结果 ,≥ 10 4 cfu ml比较女性（74 4 % ）高于男性 （6 0
刘君, 张晓凤
doaj
The Expression and Biological Significance of PD-L1 on Lung Cancer Cell Lines [PDF]
, 2009 Background and objective Tumor-associated PD-L1 expression was recently shown to promote T-cell apoptosis and proposed as a potential mechanism of immune evasion by tumors. On the basis of the ability of tumor-associated PD-L1 to mediate activated T-cell
Cheng CHEN +6 more
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Research progress of the intratumoral microbiome [PDF]
, 2023 Intratumoral microbiome is defined as the microbes that reside within tumor tissues to form the tumor microenvironment. Although substantial advances have been made in the research on virus infection and cancer during the past century, little is known ...
LI Xinran, LIANG Yiyi, TU Hong
core +1 more source
Conservation Biology, Volume 40, Issue 1, February 2026.Abstract In the era of the sixth mass extinction, reversing global biodiversity loss is of vital importance for life on Earth. In 2022, parties to the Convention on Biological Diversity (CBD) adopted the Kunming‐Montreal Global Biodiversity Framework (GBF), a strategic plan with 23 action‐oriented targets to be achieved by 2030.
Ina Lehmann +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2017 目的通过对被动凝集法检测肺炎支原体（mycoplasma pneumoniae,MP）抗体与荧光定量PCR法检测肺炎支原体核酸的对比分析,探讨两种不同肺炎支原体感染实验室检测方法在临床诊断中的价值。方法选择我院儿科支气管肺炎病例848例,进行肺炎支原体抗体检测、肺炎支原体核酸检测,对两种方法的检测结果进行统计学分析。结果在出院确诊肺炎支原体感染的462例病例中,肺炎支原体MP核酸检测阳性占总检出肺炎支原体感染的55.63%,MP抗体检测阳性占总检出肺炎支原体感染的79.00 ...
庄严, 栗俊杰, 张诗蒙, 李小燕
doaj
The application of PCR technology in detection of SPF laboratory animal rats [PDF]
, 2017 PCR作为一项新兴技术,越来越受到人们的重视。近几年来,PCR技术不断发展,它以准确、快速、便捷等优点广泛应用在科学研究的各个领域。PCR技术应用在实验动物领域中,可提高实验动物临床检测和监测水平。笔者主要介绍PCR技术在SPF级实验动物鼠病原微生物检测中的应用。PCR as a new technology, more and more get people＇s attention to it in a quick, accurate and convenient advantages are ...
张越华, 郑秀青
core
Journal of Critical Infrastructure Policy, Volume 7, Issue 1, Spring/Summer 2026.ABSTRACT The National Quality Infrastructure (NQI) in a given country provides the essential framework for quality assurance integrating standardization, metrology, accreditation, and conformity assessment to create the technical backbone for industry and trade. Hence, building a resilient NQI is fundamental to securing medicine quality, enabling local
Addisu Afrassa Tegegne +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2009 目的了解解脲支原体及人型支原体的感染情况及对常用抗生素的敏感性。方法应用支原体定量培养及药敏试验一体化的方法检测我院妇科门诊就诊患者宫颈分泌物,分析支原体的感染情况及对抗生素的敏感性。结果1 129例患者宫颈分泌物中培养出512例支原体,其中主要是解脲支原体。解脲支原体对四环素类抗生素最为敏感,强力霉素及美满霉素敏感性超过95%,而对于临床常用的阿奇霉素、罗红霉素及左氧氟沙星等敏感性不足30%。结论支原体感染是女性生殖道感染较常见的病原体,而且对常用抗生素的耐药现象也很严重。
李江, 许岩丽, 程艳丽
doaj