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广州、湛江、茂名、江门四市部份十七万人口中支气管哮喘流行病学情况的初步调查 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1987
目前,支气管哮喘(以下简称哮喘)在广东地区的流行病学情况尚无完整的数据。哮喘的患病率可因调查地区,人数,对象,方法和环境因素等不同而相差悬殊。我们于一九八三年四月至一九八四年七月对广州、湛江、茂名、江门四市的部份工厂,学校,街道居民点共172,162人进行了哮喘患病情况的初步调查。
张森泉
doaj   +2 more sources

聚合变应原治疗支气管哮喘临床与实验 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1990
用戊二醛使野苋菜花粉变应原聚合,再用凝胶层析法将大分子聚合变应原析出。免疫学实验表明该聚合变应原免疫原性不变而变应原性减低。28例支气管哮喘的临床对照研究表明,聚合变应原免疫治疗起效快,疗效好,可能减低气道的非特异反应性,未发现全身副反应。
doaj   +2 more sources

Development of a Personalized Pharmacologic Treatment Repository for Bronchial Asthma Based on the 2018 Guideline for the Diagnosis and Management of Bronchial Asthma in Primary Care(Practice Edition) [PDF]

open access: yes, 2022
Bronchial asthma is a chronic inflammatory disease with high heterogeneity, polygenic inheritance, complex etiology and many complications. The effects of prevention and treatment for a bronchial asthma patient often depend on whether the patient has ...
HUO Hongmin, YANG Yaofang, DONG Jiatian, MAO Zixian, HU Ping, SONG Fengchun
core   +1 more source

Clinical significance of FEV0.5 and FEV0.75 in the determination of pulmonary function in children with bronchial asthma [PDF]

open access: yes, 2023
Objective·To evaluate the abnormal rates of measured/predicted values of forced expiratory volume in 0.5 second (FEV0.5) and FEV0.75 in lung ventilation function testing, as well as the clinical significance of different cut-off points for improvement ...
TANG Lanfang, ZHENG Guimei
core   +1 more source

Current status and countermeasures of diagnosis and treatment of mild bronchial asthma in China [PDF]

open access: yes, 2023
In China, bronchial asthma has emerged as the second most prevalent respiratory disease, with mild asthma constituting 50%-70% of the reported cases.
ZHOU Yan, ZHANG Min
core   +1 more source

Exploratory analysis of gut microbiota differences in childhood asthma with different severity [PDF]

open access: yes, 2023
Objective·To explore the characteristics and differences of gut microbiota in children with different severity of bronchial asthma, and build a prediction model of gut microbiota in severe asthma.Methods·In this study, children aged 5 to 14 diagnosed ...
HAN Xiao   +3 more
core   +1 more source

珠三角地区变应性鼻炎和/或支气管哮喘患者皮下特异性免疫治疗依从性的真实世界研究 [PDF]

open access: yes, 2022
目的了解珠三角地区变应性鼻炎(AR)和/或支气管哮喘患者(BA)中止皮下变应原免疫治疗(SCIT)的原因,为提高患者SCIT的依从性提供参考依据。方法本研究是一项回顾性、多中心、大样本的真实世界研究,收集和分析2015年1月到2020年12月在珠三角地区6家三甲医院接受SCIT的AR和/或BA患者的临床资料,并对中止治疗患者的进行电话随访。结果纳入1 244例接受SCIT的患者,中止治疗427例(脱落率为34.3%);儿童、已婚、过敏家族史阳性、总IgE (tIgE)>200 U ...
唐隽   +7 more
core   +1 more source

Epidemiological characteristics and risk factors of severe asthma in children: a single-center prospective cohort study [PDF]

open access: yes, 2023
Objective·To explore the epidemiological characteristics of severe asthma in children and analyze the risk factors.Methods·A single-center prospective cohort study was conducted.
DAI Jiajia   +7 more
core   +1 more source

儿童下气道菌群多样性及其对支气管哮喘辅助性T细胞分化机制影响研究进展 [PDF]

open access: yes, 2018
哮喘是由多种细胞(如嗜酸性粒细胞、肥大细胞、T淋巴细胞、中性粒细胞、气道上皮细胞等)和细胞组分参与的以慢性气道炎症和气道高反应性为特征的一种异质性疾病[1]。近年来哮喘发病率逐年攀升,据全球哮喘防治创议(GINA)委员会调查显示,全球约有3亿人受到哮喘困扰[2],世界卫生组织(WHO)预计至2025年全世界哮喘患者将会增至4亿人。研究发现,哮喘患者气道菌群在丰度及多样性等方面与正常人存在显著差异[3 ...
侯凌云, 吴谨准, 葛丹丹
core   +1 more source

Clinical value of nitric oxide parameters in children with bronchial asthma [PDF]

open access: yes, 2023
Exhaled nitric oxide (eNO), as a marker of eosinophilic inflammation in the airway, has been widely utilized in the diagnosis and treatment of asthma. The fractional concentration of exhaled NO (FeNO) mainly reflects the degree of airway inflammation. By
Wei Ziqian, Yilimuguli Abudukeremu, Wu Baojing
core   +1 more source

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