Results 21 to 30 of about 23,468 (167)
ABSTRACT This study demonstrates a new strategy for modifying the boron content to address stress‐relief cracking (SRC) in the 7CrMoVTiB10.10 alloy. First, coarse‐grained heat‐affected zone (CGHAZ) specimens with different boron contents were prepared via simulated welding thermal cycles.
Dongdong Zhang +3 more
wiley +1 more source
晚期乳腺癌患者Survivin的表达情况及与放疗敏感性的关系
目的对晚期乳腺癌患者Survivin的表达情况及对放疗敏感性的分析。方法选取首诊并确诊为晚期乳腺癌(局部T4期)并丧失手术治疗机会的30例女性患者作为研究对象。对入组患者行TAC方案全身化疗及放疗,根据放疗敏感性进行分组,分为放疗敏感组和放疗不敏感组,比较2组放疗前后Survivin表达情况。结果 1Survivin蛋白在晚期乳腺癌患者放疗敏感组和放疗不敏感组组的高表达率分别为40%(8/20)和80.0%(8/10),两组差异具有统计学意义 ...
艾秀清 +3 more
doaj
Screening the Drug Sensitivity Genes Related to GEM and CDDP in the Lung Cancer Cell-lines [PDF]
Background and objective Screening of small-cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) cell lines with gemcitabine hydrochloride (GEM) and cisplatin (CDDP) related to drug sensitivity gene might clarify the action mechanism of anti ...
Chunyu YANG +3 more
core
ABSTRACT Laser powder bed fusion (LPBF) can fabricate high‐entropy alloys (HEAs) with refined microstructure and enhanced mechanical properties. However, the deformation and fatigue mechanisms of Al‐containing HEAs produced by LPBF remain unclear. In this work, we systematically investigate the tensile properties, deformation mechanisms, and high‐cycle
Dan Zheng +4 more
wiley +1 more source
ABSTRACT Masculinity significantly influences men's health‐seeking behaviors, yet its intersection with legal frameworks and healthcare access in Sub‐Saharan Africa remains underexplored. This mixed‐methods study investigates how gender norms and structural barriers influence healthcare experiences among 60 middle‐aged men (aged 30–60 years) in Yaoundé,
Ikekhwa Albert Ikhile +1 more
wiley +1 more source
目的观察双侧迷路破坏对压力感受性反射敏感性的影响。方法清洁级雄性大鼠40只,随机分为正常组、手术组和假手术组。手术组和假手术组又进一步分为双侧迷路破坏组(bilateral labyrinthectomy,BL)和压力感受性反射去除组(sinoaortic denervation,SAD)。通过静脉灌流苯肾上腺素(phenylephrine,PE)和硝普钠(sodium nitro-prusside,SNP)观察压力感受性反射敏感性的变化。结果 (1)BL不影响PE所诱发的压力感受性反射敏感性 ...
兰艳 +5 more
doaj
Involvement of Abnormal MicroRNA Expression in the Mechanism of Drug Resistance with Acute Myeloid Leukemia [PDF]
目的:分析miRNA-98的表达异常在急性髓系白血病化疗耐药机制的作用,通过靶向过表达miRNA-98的表达水平探讨以miRNA-98为靶点增加化疗药物敏感性的可能性并分析其可能作用的机制。评价异常表达的血清miRNA-155是否可作为急性髓系白血病的预后标志。 方法:离体实验中,采用qRT-PCR方法检测K562和其耐药株K562/A02中miR-98、E2F1基因表达情况。通过瞬时转染miR-98mimic处理耐药细胞K562/A0248h后,通过qRT-PCR法检测miR-98表达情况;通过qRT-
黄英丹
core
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
wiley +1 more source
目的了解解脲支原体及人型支原体的感染情况及对常用抗生素的敏感性。方法应用支原体定量培养及药敏试验一体化的方法检测我院妇科门诊就诊患者宫颈分泌物,分析支原体的感染情况及对抗生素的敏感性。结果1 129例患者宫颈分泌物中培养出512例支原体,其中主要是解脲支原体。解脲支原体对四环素类抗生素最为敏感,强力霉素及美满霉素敏感性超过95%,而对于临床常用的阿奇霉素、罗红霉素及左氧氟沙星等敏感性不足30%。结论支原体感染是女性生殖道感染较常见的病原体,而且对常用抗生素的耐药现象也很严重。
李江, 许岩丽, 程艳丽
doaj
Using LICOM to estimate roles of topography near the Luzon Strait on Kuroshio intrusion [PDF]
基于观测资料、卫星高度计资料和LICOM2.0模式一序列的地形敏感性试验,本论文首先划分吕宋海峡附近黑潮入侵方式,然后利用地形敏感性试验评估吕宋海峡附近地形对黑潮入侵的作用。主要研究成果如下: (1)基于1993–2013年AVISO卫星高度计资料,本论文定义了一个双指数(Double-index)并划分出吕宋海峡附近3种典型的黑潮入侵类型:黑潮暖涡路径、黑潮冷涡路径和黑潮泄漏路径,这展示了吕宋海峡附近黑潮与中尺度涡之间典型的空间配置关系。因此,双指数可以较好地区分黑潮入侵路径。 (2 ...
黄志达
core

