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Updated insights into the molecular pathogenesis of canine atopic dermatitis
Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Advantages and advances in neoadjuvant therapy of pancreatic cancer [PDF]
Due to the characteristics of the insidious onset, difficult early diagnosis and high malignancy of pancrea-tic cancer, only a minority of patients still have the chance of surgical resection at the time of diagnosis.
HU Binwei, SHEN Baiyong
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Zhongguo shiyan zhenduanxue, 2023 肝门静脉积气(HPVG)作为一种影像学征象，在接受化疗的患者中罕有发生，其出现多认为伴随着较差的预后及较高的死亡率。本文报道1例胃癌腹腔转移的患者，在首次接受腹腔热灌注化疗(HIPEC)联合ROX方案治疗时，突发下消化道出血伴HPVG。1 病例资料患者女性，72岁，2020年10月10日于梅河口市中心医院行腹腔镜探查时诊断为胃癌腹腔广泛转移，计划后续进行腹腔热灌注化疗(HIPEC)联合ROX方案的新辅助化疗(NC)。
韩海东, 刘琦
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The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help ...
Changli WANG +7 more
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Advances and Reflections on Neoadjuvant Therapy for Locally Advanced Thyroid Cancer [PDF]
The vast majority of thyroid cancers show a good prognosis. However, the treatment of locally advanced thyroid cancer presents a huge problem. The wide application of targeted and immunotherapy in neoadjuvant therapy for locally advanced thyroid cancer ...
CHEN Jian, FAN Qianyu, HUANG Qiuyi
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Zhongguo shiyan zhenduanxue, 2009 目的探讨乳腺癌新辅助化疗对血清肝细胞生长因子水平的影响及相关临床意义。方法应用酶链免疫吸附法（ELISA）检测100例可手术乳腺癌患者新辅助化疗前及术后的血清肝细胞因子水平,并评估其水平与乳腺癌新辅助化疗疗效的关系。结果血清肝细胞生长因子水平与乳腺癌的分期密切相关（P=0.018）;血清肝细胞生长因子水平在治疗前后的变化与新辅助化疗效果密切相关。结论血清肝细胞生长因子可能在乳腺癌的发生发展中起重要作用,可能是预测化疗疗效的独立指标。
王承正, 毛书明, 崔树德
doaj
The efficacy and side effects of liposomal doxorubicin-based therapy and epirubicin-based therapy for breast cancer patients: a meta-analysis [PDF]
Objective To conduct a meta-analysis to explore the specific efficacy and side effects of liposomal doxorubicin (LD) and epirubicin (E)-based therapies in breast cancer patients.
DENG Lang +5 more
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The research progress of endocrine therapy combined with targeted therapy for triple-positive breast cancer [PDF]
, 2023 Triple-positive breast cancer (TPBC) refers to breast cancer with positive expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 (HER2), accounting for 5%-10% of all pathological types of breast cancer.
CAO Xiaoshan, CONG Binbin
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Zhongguo shiyan zhenduanxue, 2020 近年来直肠癌发病率及死亡率呈逐年上升的趋势,其中T3期约占60%-80%。目前直肠癌的治疗主要包括手术治疗和新辅助治疗,对于T分期达T3或N+的患者,建议先进行新辅助放化疗。因此,患者术前准确分期,对于制定治疗方案及预后至关重要。高分辨率MRI无法准确鉴别患者术前肿瘤是否侵犯周围脂肪间隙,造成术前T2与T3期的过高或过低分期[1]。本研究通过对T2、T3期直肠癌ADC序列影像组学特征进行研究,包括提取病灶区域影像特征、特征筛选,进而通过分析比较建立高效稳定的诊断模型 ...
孙伯尧 +8 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2022 随着脊柱外科手术技术发展，手术操作的精准化、手术过程的微创化和手术方案的个性化已成为脊柱外科未来发展的热点方向。如何通过最小的创伤获得最大的手术疗效，如何减少术中患者承受的射线辐射量，以及如何在保持手术效果的前提下缩短手术时长，都是我们当前需要思考的问题。目前，虚拟现实（virtual reality， VR）技术作为脊柱外科领域的研究热点，在操作培训、理论教学、术中辅助，以及术后康复各个环节都显示出极大优势。然而目前VR技术在脊柱外科的应用仍处于探索阶段，本文尝试对VR技术在脊柱外科术中辅助 ...
李春海
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