Research progress on TEM8 in malignant tumors [PDF]
, 2023 Tumor endothelial marker 8 （TEM8） is a highly-conserved single-shot transmembrane glycoprotein. TEM8 is a special member of the tumor endothelial marker family，which was first discovered in colon cancer tissues.
Huang Furong, Feng Chengtian, Cao Shiyu, Jiang Yongdong
core +1 more source
The efficacy and side effects of liposomal doxorubicin-based therapy and epirubicin-based therapy for breast cancer patients: a meta-analysis [PDF]
Objective To conduct a meta-analysis to explore the specific efficacy and side effects of liposomal doxorubicin (LD) and epirubicin (E)-based therapies in breast cancer patients.
DENG Lang +5 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2010 目的研究细胞色素P450 3A4（CYP3A4）在乳腺癌组织中的表达及其与化疗反应间的关系,并对其表达差异的遗传基础进行初步探讨。方法乳腺癌病例组包括40例单纯手术患者3、6例新辅助化疗后手术患者和200例辅助性化疗患者;其中新辅助化疗患者接受以紫杉醇为基础的化疗。利用实时荧光RT-PCR检测手术患者癌组织及其癌旁组织中CYP3A4 mRNA的表达,连接依赖性SNP技术检测CYP3A4*18基因分型。结果 CYP3A4在大多数乳腺癌组织及其癌旁组织中均有表达;在40例单纯手术患者中,其表达水平（ΔCt ...
程梅 +6 more
doaj
TACE with Ar-He Cryosurgery Combined Minimal Invasive Technique for the Treatment of Primary NSCLC in 139 Cases [PDF]
, 2010 Background and objective TACE, Ar-He target cryosurgery and radioactive seeds implantation are the mainly micro-invasive methods in the treatment of lung cancer.
Dongmei LI +5 more
core
Analysis of pathological remission degree and influencing factors of radical surgery after neoadjuvant immunotherapy combined with chemotherapy in patients with locally advanced esophageal squamous cell carcinoma [PDF]
Background and purpose: Radical surgery after neoadjuvant immunotherapy combined with chemotherapy (nICT) in patients with locally advanced esophageal squamous cell carcinoma (LAESCC) has good efficacy and safety, and it can improve the patients ...
LIAO Ziyi, PENG Yang, ZENG Beilei, MA Yingying, ZENG Li, GAN Kelun, MA Daiyuan
core +1 more source
The research progress of endocrine therapy combined with targeted therapy for triple-positive breast cancer [PDF]
, 2023 Triple-positive breast cancer (TPBC) refers to breast cancer with positive expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 (HER2), accounting for 5%-10% of all pathological types of breast cancer.
CAO Xiaoshan, CONG Binbin
core +1 more source
Effect of intraoperative use of low-dose dexmedetomidine on the prognosis of patients undergoing breast cancer surgery [PDF]
, 2023 Objective·To investigate the influence of intraoperative dexmedetomidine infusion on the recurrence-free survival (RFS) and overall survival (OS) rate of patients undergoing breast cancer surgery.Methods·A retrospective analysis was performed on patients
CHU Xiaoying +3 more
core +1 more source
Chinese expert consensus on clinical practice of locally advanced gastric cancer invading adjacent organs (2024 edition) [PDF]
Gastric cancer is one of the most common malignant tumors, and over 70% of patients were diagnosed as advanced stage at the first visit in our country. For patients with locally advanced gastric cancer invading adjacent organs, the diagnosis and surgical
Professional Committee on Gastric Cancer of Shanghai Anticancer Association , Professional Committee on Gastrointestinal Cancer of China Association for Promotion of Health Science and Technology
core +1 more source
Lgr-5的表达与Ⅲ期直肠癌患者新辅助放化疗结合直肠癌根治术与预后的关系
Zhongguo shiyan zhenduanxue, 2016 近年来我国直肠癌的发病率显著上升,其病死率在所有恶性肿瘤中位居第三,且发病呈年轻化趋势。目前对于直肠癌的治疗,仍以手术切除为主,但由于直肠癌发病部位较深,且周围解剖结构十分复杂,不易彻底切除,而新辅助放化疗可以将手术切除困难,或无法行手术切除的病灶变为可切除[1 ...
路明, 刘恒昌, 李艳丽
doaj
Zhongguo shiyan zhenduanxue, 2019 非小细胞肺癌（NSCLC）作为较常见的肺癌,起病隐匿,通常发现较晚[1]。而手术根治是其主要的治疗手段,但存在复发率高预后不佳等问题[2]。近年来,研究发现新辅助化疗可在一定程度上降低术后的复发率[3],但缺乏明确指标提示何类患者受益更大。miR-21被证实在多种肿瘤中表达异常且与化疗耐药相关[4]。因此本研究拟探究血清miR-21对NSCLC新辅助化疗预后的检测价值。1材料和方法1 ...
董大鹏, 安然, 刘威
doaj