Results 41 to 50 of about 5,742 (154)
Zhongguo shiyan zhenduanxue, 2010 目的探讨新辅助化疗（neoadjuvant chemotherapy,NACT）方案治疗局部晚期宫颈癌（locally advanced cancerLACC）分子疗效,为临床遴选治疗方案及评价疗效的分子标志物提供理论依据。方法选取局部晚期宫颈鳞癌60例作为研究对象,随机分成3组,进行2个疗程以铂类为基础的新辅助化疗,分别为TP（紫杉醇+顺铂）、FP（5-氟尿嘧啶+顺铂）及IP（异环磷酰胺+顺铂）,以流式细胞术检测化疗前后的宫颈鳞癌组织中增殖细胞指数ki67的表达,TUNEL法检测肿瘤细胞的凋亡指数 ...
吴良芝 +4 more
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 2020 神经胶质瘤是中枢神经系统中最常见的原发肿瘤，其中过半数是WHOIV级的胶质母细胞瘤，即使接受包括了手术、同步放化疗及辅助化疗的治疗，其中位生寸期仍只有14.2个月。免疫抑制是恶性胶质瘤的重要特征，逆转免疫抑制的免疫治疗仍然是近年来最有希望提高胶质瘤患者治疗效果的方式。本文综述了胶质瘤的免疫治疗进展，以及胶质瘤微环境中调节性T细胞（Treg）与糖皮质激素诱导的肿瘤坏死因子受体（GITR）的研究进展，希望为恶性胶质瘤的免疫治疗提供新的研究思路。
牟永告
doaj
Advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2023 [PDF]
Pancreatic cancer is a highly malignant digestive tract tumor with hidden symptoms, limited treatment options and rapid progression. With an increasing incidence rate year by year, pancreatic cancer has increasingly become a prominent issue endangering ...
LI Tianjiao, YE Longyun, JIN Kaizhou, WU Weiding, YU Xianjun
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 探讨新辅助化疗对Ⅰb2 ～ Ⅲb期宫颈癌的近期临床疗效? 【方法】 选择我院2003年6月～2007年9月收治的经病理确诊的28例Ⅰb2 ～ Ⅲb期宫颈癌患者,动脉介入化疗18例,化疗方案:卡铂(300 mg/m2)+博来霉素(45 mg);静脉化疗10例,化疗方案:卡铂(AUC 6)+5*9鄄FU(4 000 mg/m2 > 96 h)?化疗10 ～ 14 d重新评估,化疗2 ～ 3周行广泛全子宫切除术+盆腔淋巴结清扫术,观察近期临床疗效?【结果】 化疗有效率82.1%(23/28 ...
温国群
doaj
Clinical analysis of 21 cases of primary Ewing sarcoma of the thoracic wall [PDF]
Background and Purpose: Primary Ewing sarcoma of the thoracic wall (PEST) is a rare extraosseous Ewing sarcoma that occurs in the chest wall or thoracic cavity with a short survival, poor prognosis and a high rate of recurrence.
JIANG Lili, MA Yan, ZHANG Tiantian, HUANG Shan
core +1 more source
Zhongguo cuzhong zazhi脑出血（intracerebral hemorrhage，ICH）临床治疗面临手术时机不明确、血肿清除效率低及手术创伤大等多重挑战。传统手术方式（如开颅血肿清除术、立体定向血肿抽吸术等）因创伤大、精度不足等局限，难以满足临床需求。近年来，在人工智能与新型成像技术的驱动下，ICH治疗加速向智能化、精准化转型：术前诊断模型通过提升ICH病因识别的准确率和对血肿扩大风险的预测能力，为手术决策提供精准依据；术中智能辅助系统借助脑移位监测与实时路径调整，进一步优化手术效果 ...
赵润生，李新伟，王乔，张旭，张东ZHAO Runsheng, LI Xinwei, WANG Qiao, ZHANG Xu, ZHANG Dong
doaj +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 1981 鼻咽癌目前的主要治疗方法是放射治疗,或辅以化学药物、手术、中草药等综合治疗。医用激光是近年来发展起来的新技术。为了探讨激光对鼻咽癌的治疗作用,我院在中山医学院物理教研室的协助下,研制成功气化鼻咽癌病灶的CO2激光仪。自1979年7月开始,对鼻咽癌放疗后鼻咽局部复发病例,进行激光气化治疗,取得一定疗效,现将治疗情况报道如下。
孙振权
doaj
Research and guidelines interpretation of neoadjuvant therapy for resectable pancreatic cancer, promising or limited? [PDF]
As a systemic disease, pancreatic cancer is highly malignant and has a high rate of recurrence and metastasis, which makes it particularly difficult in diagnosis, treatment and management.
ZHANG Taiping, WENG Guihu, LIU Yueze
core +1 more source
Preservation of Limb Growth Potential in Treatment of Pediatric Osteosarcoma Around the Knee: Research Progress and Future Prospect [PDF]
With the development of imaging technology, advancements in surgical techniques, application of multidrug chemotherapy, and collaboration in postoperative rehabilitation, the local recurrence rate and survival of patients with osteosarcoma after limb ...
Taiqiang YAN, Wei GUO, Zhiqing ZHAO
core +1 more source
Zhongguo shiyan zhenduanxue, 2016 目的探讨胶原凝胶滴包埋肿瘤细胞培养法化疗药物敏感性检测技术（CD-DST）对结直肠癌术后辅助化疗的指导作用及临床应用可行性。方法将30例结直肠癌患者的新鲜手术标本分别对5-氟尿嘧啶、奥沙利铂、伊立替康3种化疗药物进行CD-DST检测,观察检测成功率、药物敏感性差异。以CD-DST检测结果为指导治疗的患者28例作为实验组,未行CD-DST检测以传统经验治疗的30例患者作为对照组,研究检测结果与临床疗效的一致性,比较2组患者术后1年的无进展生存期（PFS）。结果 （1）检测成功率为93.3%（28/30 ...
郭惠玲 +5 more
doaj