Results 21 to 30 of about 13,784 (158)

Activatable Hybrid Nanoparticles for Cancer Theranostic [PDF]

open access: yes, 2016
众所周知癌症已经成为人类在健康领域中面临的重大问题。临床研究控制和治愈肿瘤最有效的方式是实现早期的诊断和治疗,而如何使肿瘤早期诊断成为现实,提高治疗效果已成为这一研究领域的一个热门话题。纳米医学,即纳米技术在医学中的应用,推动了脂质体,纳米颗粒,胶束等载药型纳米颗粒的发展。而重要的是这些医学纳米材料作为有效的诊断治疗试剂用于多种疾病的诊断和治疗。一个优秀的纳米材料应该具备多重优势:(1)实现肿瘤或其他疾病的早期可视化,(2)有效转运药物到目标部位,(3)诊断治疗试剂在体内的分布和(4 ...
张力文
core  

CT、MRI在成人早期股骨头缺血坏死诊断中的运用价值分析

open access: yesZhongguo shiyan zhenduanxue, 2013
目的对CT和MRI在成人早期股骨头缺血坏死诊断中的运用价值进行分析。方法从2011年12月至2012年12月在我院接受治疗的股骨头缺血性坏死(ANFH)患者中选取56例作为研究对象,共88髋,年龄均在31-57岁之间,对所有患者都进行两侧髋关节的CT和MRI检查,以ARCO法分期为标准,比较两者定性诊断敏感度和早期检查定性敏感度以及早期影像学。结果 CT和MRI对ANFH的识别与诊断都有准确的效果,两者比较无明显差异,但是MRI早期检查定性敏感度达到了100%,远高于CT的早期检查定性敏感度 ...
任勇, 母其文, 陈世孝, 张福洲
doaj  

Potential Diagnosis and Prognosis Value of Plasma MicroRNA-19a in Esophageal Cancer [PDF]

open access: yes, 2015
背景:食管癌是发生于食管上皮组织的恶性肿瘤,具有高死亡率、高复发率和高转移率的特点。然而目前针对食管癌敏感的肿瘤标志物不多,且诊断效率较低,远远不能满足临床需求。MicroRNA是一类非编码RNA,可以稳定存在于人体血浆中并且易于检测。据报道,microRNA在诸多疾病状态下会出现表达异常,如食管癌、结直肠癌、肝癌等,这一发现极大地增加了血浆microRNA作为食管癌标志物的可能。在前期实验中,我们观察到microRNA-19a(miR-19a)在食管癌血浆标本中高表达,本文将重点探讨miR ...
白永颖
core  

N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan   +15 more
wiley   +1 more source

微小点状钙化在彩超诊断乳腺癌中的意义

open access: yesZhongguo shiyan zhenduanxue, 2014
乳腺癌是常见的女性恶性肿瘤种类之一,早期诊断以及实施早期治疗是改善此类患者预后关键。在早期诊断所用检查手段中,超声检查较为常用。而微钙化显示是乳腺癌诊断的重要影像显示依据。本文选择我院乳腺癌患者,观察彩超微钙化在乳腺癌诊断中临床意义,现报告如下。1资料和方法1 ...
曹剑标
doaj  

Diagnotic Value of the Combined Determination of Telomerase Activity in Induced Sputum, Pleural Effusion and Fiberobronchoscopic Biopsy Samples in Lung Cancer [PDF]

open access: yes, 2010
Background and objective It has been proven that telomerase activation correlates with the carcinogenesis, aggressiveness and turnover of lung cancer.
Cheng ZHAO   +4 more
core  

Implementation of clinical breast examination screening programme as part of primary care in Vietnam: An analysis of contextual factors

open access: yesWorld Medical &Health Policy, Volume 17, Issue 1, Page 90-107, March 2025.
Abstract Clinical breast examination (CBE) screening for breast cancer in Vietnam was proved to be cost‐effective and acceptable to women. However, the outcomes of the implementation of such proposed programme are unknown. To inform the design and implementation planning of the proposed screening programme, this study investigated and analysed the ...
Tran Thu Ngan   +3 more
wiley   +1 more source

原发性甲状旁腺功能亢进症的早期诊断

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1987
原发性甲状旁腺功能亢进症(简称甲旁亢)早期症状隐匿,诊断颇为困难。自六十年代后期,国外广泛应用血清生化自动分析仪,开展血清钙筛选工作以来,高血钙病例显著增多,为早期诊断原发性甲旁亢提供了重要线索。我们通过对门诊及部分住院病人常规进行血清钙筛选,结合有关诊断指标,进一步探讨了原发性甲旁亢的发病情况及其早期诊断等问题。
陈规划
doaj  

Design, synthesis and preliminary bio-evaluation of progestrone receptor targeting probes for breast cancer imaging with PET [PDF]

open access: yes, 2016
乳腺癌是严重威胁女性健康的疾病,它的早期诊断能够有效的降低病人的死亡率。孕激素受体属于核受体超家族,有PRA和PRB两种亚型,在调节和控制卵巢,子宫和乳腺的功能方面有重要作用。研究表明,在雌激素受体阳性(ER+)的乳腺癌病人中,PR的表达与否不会对病人接受他莫西芬治疗的疗效产生影响。但是在雌激素受体表达阴性(ER-)的乳腺癌病人中,病人接受他莫西芬治疗的疗效依赖于PR的表达。因此,监测PR的表达对乳腺癌的早期诊断和ER-/PR+病人的治疗都是很重要的。PET的灵敏度高,空间分辨率好,安全性也较好 ...
吴晓伟
core  

Clinical utility of ultrasonography in pediatric and adolescent gynecology: retrospective review of 1313 ultrasound examinations

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 226-234, February 2025.
ABSTRACT Objectives Ultrasound is the first‐line imaging modality of the pelvis in the pediatric and adolescent gynecology (PAG) population. Ultrasound findings in pre‐ and postpubertal PAG patients differ from those in adults. Diagnostic models for adnexal pathology have not been validated in this cohort.
N. Cooper   +15 more
wiley   +1 more source

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