Results 31 to 40 of about 13,784 (158)

血清AFU、LAP和GGT联合检测在早期原发性肝癌诊断中的应用与评价

open access: yesZhongguo shiyan zhenduanxue, 2016
我国是肝炎发病大国,肝癌发病率也呈逐年上升的趋势,是临床常见的疾病。据统计,每年大约有11万人因肝癌死亡。肝癌一般起病比较隐蔽[1],早期无典型的临床症状,临床上一旦确诊一般属于中、晚期。因此,如何早期诊断肝癌具有重要的意义[2]。现阶段,临床上应用甲胎蛋白和影像学方法辅助诊断早期肝癌,但早期肝癌的诊断率仍然较低。a-L盐藻糖苷酶(a-L Salina glucosidase AFU ...
隋菱
doaj  

Synthesis of MnO@Au nanocomposite and its applications in multifunctional imaging and photothermal treatment [PDF]

open access: yes, 2016
肿瘤的诊断,特别是针对高致死性和侵袭性肿瘤的早期诊断,已经越来越得到人们的重视。但是,目前癌症的早期诊断也同癌症治疗一样,仍然是一项充满难度与挑战性的一项工作。现在的诊断方法包括了X射线计算机断层扫描技术(CT),磁共振(MRI),超声成像(US),以及当下兴起的光声层析成像技术(PAI),由于每种成像方式都有其固有的缺点,所以任何单一成像方式都不能获得完全关于癌症的信息。本文设计了一种非常简便的方法,在室温条件下,第一次合成出以MnO和Au为基的草莓状MnO@Au复合纳米材料,实现了集MRI,CT ...
雷胜岚
core  

Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 635-650, November 2024.
ABSTRACT Objectives To reach an international expert consensus on the diagnosis, prognosis and management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure, and to use this to define a core outcome set (COS). Methods A three‐round Delphi procedure was conducted among an international panel of experts in fetal LUTO.
H. J. Mustafa   +90 more
wiley   +1 more source

缺血修饰白蛋白与平板运动试验联合检查对早期冠状动脉综合征的临床诊断意义

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨缺血修饰白蛋白(IMA)测定与平板运动试验联合诊断早期冠脉综合征的临床应用价值。方法以30例体检健康者做为对照,对80例心肌缺血、缺氧症状患者分别进行平板运动试验(TET)、冠状动脉造影(CAG)以及检测其运动前后的IMA值。比较运动试验前后患者与健康对照组IMA测定值的变化;以冠脉造影结果为标准,分别评价IMA、TET、IMA联合TET对于诊断早期冠状动脉综合征敏感性与特异性。结果运动试验前试验组IMA值与对照组差异显著 ...
杨曦明, 姚兴伟, 刘福鼎, 周智
doaj  

PET Imaging and Targeted Radiotherapy of Integrin αvβ3 Positive Tumors [PDF]

open access: yes, 2016
目的:含有三肽序列的精氨酸-甘氨酸-天冬氨酸(Arg-Gly-Asp,RGD)的配体和整合素αvβ3具有特异性和高亲和力,因此利用RGD与整合素αvβ3特异性结合而设计的放射性核素标记的RGD分子探针在肿瘤显像方面得到了广泛的研究和应用。然而,放射性核素标记的RGD分子探针在肿瘤治疗方面的研究却并不多。本研究中,我们创造性的将环状多肽RGDfK与白蛋白结合基团伊文思蓝(EvansBlue,EB)共价结合,以期构建一种可长时间存在于体内循环的长效分子探针EB-RGD ...
陈皓鋆
core  

Combined first‐trimester screening and invasive diagnostics for atypical chromosomal aberrations: Danish nationwide study of prenatal profiles and detection compared with NIPT

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 4, Page 470-479, October 2024.
ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll   +6 more
wiley   +1 more source

Analysis on Lung Cancer Survival from 2001 to 2007 in Qidong, China [PDF]

open access: yes, 2011
Background and objective Lung cancer is one of the most important malignancies in China. Survival rates of lung cancer on the population-based cancer registry for the years 2001-2007 in Qidong were analysed in order to provide the basis for the prognosis
Jian ZHU   +4 more
core  

Adverse pregnancy outcome in fetuses with early increased nuchal translucency: prospective cohort study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 2, Page 164-172, August 2024.
ABSTRACT Objectives An increased nuchal translucency (NT) thickness of ≥ 3.5 mm is a well‐established marker for congenital anomalies and adverse pregnancy outcome between 11 and 14 weeks' gestation, but little is known about its performance as a screening tool before 11 weeks.
B. B. Bet   +5 more
wiley   +1 more source

恶性肿瘤患者循环DNA的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2011
目前,对于恶性肿瘤,缺乏一种行之有效的早期诊断手段。绝大多数的恶性肿瘤明确诊断时已经是中晚期,经治疗后患者五年生存率极低[1],并且预后极易复发。所以建立一种方便、微创、灵敏、特异的恶性肿瘤早期诊断手段势在必行,循环DNA极易获得 ...
倪培民   +4 more
doaj  

Ovarian ectopic pregnancy: clinical characteristics, ultrasound diagnosis and management

open access: yesUltrasound in Obstetrics &Gynecology, Volume 63, Issue 6, Page 815-823, June 2024.
ABSTRACT Objective To compare the clinical, ultrasound and biochemical characteristics of ovarian ectopic pregnancy (OEP) with those of tubal ectopic pregnancy (TEP). Methods This was a retrospective case–control study of women with OEP and those with TEP seen at a single center between December 2010 and February 2021.
S. A. Solangon, J. Naftalin, D. Jurkovic
wiley   +1 more source

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