The role of circadian rhythm and its new strategies for prevention and treatment in oral diseases [PDF]
Circadian rhythm is a biological endogenous process regulated by the suprachiasmatic nucleus of the hypothalamus, which transmits light signals to peripheral clocks and synchronizes the body with the external environment through balanced expression of ...
WANG Yajun, ZHANG Lin, CHENG Chen, XING Wenmin, GE Xuejun, CHENG Fengli, ZHANG Fang
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在生物组织几乎所有的水平都存在生物节律,其频率范围很大,高达几毫秒一次,低至数年一次。在各种生物节律中,研究得最多的是以约24小时为周期的似“昼夜节律”(“Circadianrhythms”),常被简称作昼夜节律。人体多种生理功能的节律周期是接近一个昼夜,如体温、血压、代谢变化和激素分泌等。近期,有人研究证明,如果没有环境昼夜信号的影响,人体“自由运行”(“free run”)的节律周期略长于24小时 ...
吴振云, 李德明
core
Lipidomic Analysis of the Effect of Piperine on Circadian Rhythm of Lipid Metabolism-Associated Genes in Obese Rats [PDF]
In this study, an obese rat model induced by a high-fat diet (HFD) was used to investigate the modulating effect of 1-piperoylpiperidine (PIP) on circadian misalignment caused by metabolic dysregulation. The results showed that PIP attenuated HFD-induced
ZHANG Weiyun, HO Chi-Tang, LÜ Muwen
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Evaluation of circadian rhythms in depression by using actigraphy: a systematic review and meta-analysis [PDF]
Objective·To systematically review the effectiveness of actigraphy on the evaluation of circadian rhythm characteristics in patients with depression.Methods·A systematic literature search was conducted in PubMed, Embase, Web of Science, Cochrane Library,
FANG Yiru +4 more
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Latest Developments in the Effects of Intermittent Fasting on Weight Loss and Glycolipid Metabolism [PDF]
Dietary intervention is an important approach to treating obesity. Intermittent fasting (IF) is a eating pattern alternating between eating and energy-restricted fasting or fasting periods, whose types mainly include alternate-day fasting, periodic ...
BA Tao, WANG Xiaoli, CHANG Xiangyun
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昼夜节律是与人体关系最为密切的生物节律之一,近年来临床医生越来越重视昼夜节律对药物作用效果的影响[1-4]。时间药理学研究指出,同一组织或是器官对于相同剂量的同一种药物在不同时间时段,药物敏感性和作用效果是有差异的。咪达唑仑是一种在临床麻醉和ICU镇静中被广泛应用的苯二氮卓类短效中枢神经抑制剂,具有抗焦虑、催眠、抗惊厥和顺行性遗忘作用。目前已有研究证实昼夜节律对异丙酚、氯胺酮、戊巴比妥 ...
王岩, 叶虹, 王庆波
doaj
Study on Circadian rhythm and clock genes in Microcystis aeruginosa PCC7820 [PDF]
生物钟是广泛存在于蓝藻、植物和动物细胞中的内源计时系统,它对各种代谢和行为的实时调控使机体能更好地适应环境日变化(如光照、温度和湿度等)。生物钟一般具有三个主要特点,即在稳恒条件下生物钟仍然能以近似24h的周期自由运行;光/暗和温度信号能重置生物钟时相;生物钟周期长度具有温度补偿性。 蓝藻是具有生物钟的最简单生物,当其生物钟周期与环境光/暗周期相近时,藻细胞具有更强的生存竞争优势。生物钟这种内源计时系统在蓝藻中普遍存在,并且能全面调控细胞代谢,如细胞分裂,固氮作用、光合作用、氨基酸吸收 ...
徐虹
core
Regulatory Effect and Mechanism of Capsaicin on the Circadian Rhythm of Hepatic and Pancreatic Glucose Metabolism in High-Fructose and High-Fat Diet-Fed Mice [PDF]
In this study, the modulatory effect of capsaicin (CAP) on the circadian rhythm of glucose metabolism in the liver and pancreas of mice fed a high-fructose and high-fat diet (HFFD) was investigated.
HAN Liguang, LIANG Wanxia, WANG Wenshuo, XIAO Jie, HO Chi-Tang, Lü Muwen
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Effects of two intermittent fasting strategies on postprandial lipid metabolism in adults [PDF]
ObjectiveTo investigate the effects and potential mechanisms of morning and evening fasting on postprandial lipid responses, a post hoc analysis based on a crossover randomized controlled trial was conducted to assess the effects of different fasting ...
HE Gengsheng +6 more
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Effect of DBP inhibition on vascular calcification in chronic uremic rats [PDF]
Objective To evaluate the effect of D-site binding protein (DBP) inhibition on vascular calcification in chronic uremic rats. Methods GSE146638 was downloaded from the public database (Gene Expression Omnibus, GEO), and a total of 10 samples from rat of ...
Cao Sujuan, Liu Shuzheng, Yuan Buqi, Yuan Peile, Zhao Songhe, Zhang Yunfang
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