摘 要: 【目的】 观察ENH(Enigma Homolog)蛋白在大鼠坐骨神经选择性损伤(SNI)疼痛模型引起的病理性疼痛中的表达,并探索其与疼痛的相关性及可能机制。【方法】取15只雄性SD大鼠,分为3组(每组5 只),分为SNI组,麻醉治疗组和假手术对照组。另取30只雄性SD大鼠,分为6组(每组5 只),按时间点分为非手术组对照组和实施SNI手术的1、4、7、10、14d组。通过检测大鼠50%机械刺激撤足阈值,观察SNI,SNI+利多卡因和罗哌卡因复合制剂及假手术组在4、7、10 ...
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