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CD4细胞内ATP浓度代替CD4/CD8比值用于评估结核感染患者的免疫状态
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的：研究CD4 T淋巴细胞内的基础ATP浓度代替CD4/CD8比值用于评估结核病感染者免疫状态的可行性。方法：本研究通过磁珠法分离相同体积全血中的CD4、CD8细胞，并计算CD4和CD8细胞的基础ATP浓度来评估结核病感染者的免疫状态，以QFM（Quantiferon Monitor）检测法作为对照。结果：研究发现传统的CD4/CD8比值或CD4 T细胞计数方法不适用于结核病患者。采用CD4细胞的基础ATP浓度来监测活动性结核患者和健康人群，在以290.7×10-6 g/L为cut-off值 ...
刘振杰 +7 more
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Local composite quantile regression for the varying coefficient model(变系数模型的局部组合分位数估计)
Zhejiang Daxue xuebao. Lixue ban, 2015 变系数模型推广了经典的线性模型，能灵活描绘变量间的非线性和交互性特征.考虑跨越一系列分位点的变系数模型的稳健估计，采用局部组合分位数回归方法，给出了该模型估计的局部Bahadur表示和渐近正态分布性质.证明了所得的估计量能够满足非参数收敛率要求.同时，模型计算容易执行且不需要指定误差分布的具体形式.进而推导了最优窗宽的表达式并提供了 一个基于分位数交叉核实准则的窗宽选择方法.通过Monte Carlo模拟，检验了局部组合分位数估计变系数模型的有限样本性质.
XIEQichang(解其昌)
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Wildlife Letters, EarlyView.Using a 3‐year, broad‐scale camera‐trap network in western Kansas, we tested whether coyotes and American badgers exhibit spatiotemporal patterns consistent with coordinated hunting. Despite high diel activity overlap, detection‐conditioned co‐detections occurred far less frequently than expected under independence, and short‐term temporal sequencing ...
Ty J. Werdel +3 more
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Comprehensive framework for assessing and optimizing existing research networks
Conservation Biology, EarlyView.Abstract Conservation, monitoring, and research networks, or collections of ecological research sites unified under a common mission of data collection or a research mission, are essential infrastructure for understanding large landscapes. However, most networks developed opportunistically over decades rather than through systematic design, creating ...
Alyson East +2 more
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Scientists’ warning on the global destruction of rock outcrop ecosystems
Conservation Biology, EarlyView.Abstract Rock outcrops are geological formations that harbor a highly specialized biota adapted to harsh environmental conditions that differ from their surrounding landscapes. They are globally distributed, especially in old, highly weathered landscapes, and can function as habitat islands containing high levels of endemism and distinct evolutionary ...
Luiza F. A. de Paula +19 more
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Conservation Biology, EarlyView.Abstract Qualitative approaches are increasingly applied in conservation social science, yet methodological reflection remains limited. Member checking, a process of returning findings to participants for feedback, is widely recognized outside conservation as a means to enhance rigor and reciprocity, but it is rarely reported in conservation research ...
Judith J. Rakowski +6 more
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He jishu近年来，机器学习方法被广泛应用于对原子核质量的预测中。基于连续型贝叶斯概率（Continuous Bayesian Probability，CBP）估计器，结合贝叶斯模型平均（Bayesian Model Averaging，BMA）改进了理论模型对核质量的描述。在CBP方法中，核质量理论值与实验值的差异被视为连续变量，通过核密度估计（Kernel Density Estimation，KDE）生成其先验和似然概率密度函数，并以贝叶斯定理确定后验概率密度函数。在全局优化和外推分析中 ...
谭 凯中, 高 琬晴, 刘 健
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua +9 more
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四川大学学报. 自然科学版, 1989 在统计估计及检验中,有时涉及到基于样本（X1,Y1）,…,（Xn,Yn）直接估计未知条件密度f（yx）的不少参数方法,而双重核估计就是较常用的一种.许多学者已讨论了f（yx）的双重核估计量fn（yx）的相合性及收敛速度,但从应用角度来看,此估计量仍有不便之处.在密度估计的情形,Devroye提出了“自动选择窗宽”核估计的概念,即窗宽完全由样本确定.本文推广这种思想于上述估计量,讨论其一致强相合性,并作为应用,顺便得到其“近邻估计”的强相合性.
袁敖
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Assessing differences among elasmobranch nurseries to aid conservation based on a genomics framework
Conservation Biology, Volume 40, Issue 4, August 2026.Abstract Elasmobranch nurseries often differ in environmental conditions, demographics, and use patterns. These differences affect the distribution of genetic variation among nurseries. However, conservation and management strategies often fail to account for such differences because they are difficult to characterize.
Dominic G. Swift +8 more
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