本课题来源于①国家重点基础研究发展计划(973计划)课题:有毒中药毒效学和靶器官毒作用规律研究(课题编号:2009CB522801)。②国家重点基础研究发展计划(973计划)课题:有毒中药毒效物质基础研究(课题编号:2009CB522804)及③国家自然基金面上项目:基于“物质—功效—毒性”新型并行性有毒中药质量评价模式研究(课题编号:81073047)。 本研究针对有毒中药科学应用所涉及的毒性相关物质基础、毒效规律、作用机理和科学应用等关键科学问题,以中药药效/毒性理论创新突破为重点 ...
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[Emphasis on scientific research related to viral hepatitis]. [PDF]
Ren H, Hu P.
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蛙病毒同源蛋白RGV-27R和ADRV-85L的表达及其免疫原性分析
沼泽绿牛蛙病毒(Rana grylio virus,RGV)和大鲵蛙病毒(Andrias davidianus ranavirus,ADRV)同属虹彩病毒科(Iridoviridae)蛙病毒属(Ranavirus)成员,是引起水产动物高死亡率的病原。其同源早期蛋白RGV-27R和ADRV-85L与蛙病毒代表株蛙病毒3型(Frog virus 3,FV3)25R基因所编码的大小为31kD的早期蛋白P31K(FV3-P31K)同一性超过99%。我们在观察和比较RGV与ADRV感染大鲵胸腺细胞(Giant ...
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