Results 21 to 30 of about 1,249,305 (180)
ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua +9 more
wiley +1 more source
Metal‐Based Materials for Redox Modulation in Biomedicine
ABSTRACT Metal materials have become increasingly important in modulating biological redox networks for therapeutic and diagnostic purposes, owing to their distinctive electronic properties and adaptable reactivity. This review synthesizes recent developments across various metal‐based materials, including elemental metals, metal oxides, coordination ...
Yan Fan +7 more
wiley +1 more source
ABSTRACT Biodegradable zinc (Zn)‐based materials are considered promising candidates for orthopedic applications because of their favorable mechanical properties, controllable biodegradability, and good biosafety profiles. However, their clinical translation is limited by early‐stage corrosion‐induced cytotoxicity and inflammation, as well as ...
Jinlong Mao +9 more
wiley +1 more source
ABSTRACT Lignin is a natural non‐toxic polyphenolic macromolecule, which shows inherent antioxidant and broad‐spectrum antibacterial activities. However, due to the low content and the high bond dissociation energy of phenolic hydroxyl groups (Ar‐O·H), its antioxidant and antibacterial activities are relatively weak, which limits its application as a ...
Meiling Han +10 more
wiley +1 more source
水生呼肠孤病毒为感染水生动物的一类病原体,隶属于呼肠孤病毒科新建水生呼肠孤病毒属。草鱼呼肠孤病毒(Grass carp reovirus,GCRV)是引起中国南方淡水养殖草鱼暴发性出血病病原,鲅鱼呼肠孤病毒(Threadfin reovirus,TFV)是引起海水养殖鲅鱼病毒病病原。本研究将GCRV与新加坡TFV分离株进行了部分特性比较研究。结果表明,GCRV与TFV均能感染CIK细胞,但对其它鱼类细胞系的敏感性有所差异。此外,凝胶电泳与逆转录聚合酶链式扩增显示,GCRV与TFV核酸属不同的基因型 ...
汪亚平, 方勤, 丁清泉, 朱作言
core +2 more sources
ABSTRACT Methanol‐assisted hydrogen generation reduces energy consumption while maintaining high hydrogen productivity. However, constructing bifunctional catalysts with high hydrogen evolution reaction (HER) activity, CO tolerance, and long‐term stability remains challenging.
Xiaoyu Zheng +5 more
wiley +1 more source
内毒素是革兰氏阴性菌菌体中存在的毒性物质的总称。是革兰氏阴性菌细胞壁成分,由菌体裂解后释出的毒素,又称之为"热原"。其化学成分是磷脂多糖-蛋白质复合物,其毒性部分主要为类脂质A[1]。内毒素位于细胞壁的最外层、覆盖于细胞壁的黏肽上。各种细菌内毒素的毒性作用较弱,作用机理大致相同,可引起发热、微循环障碍、内毒素休克及播散性血管内凝血等。革兰氏阴性菌菌血症占相当大的比例,越来越引起人们的重视 ...
孙安民, 王伟
doaj
ABSTRACT Biodegradable Zn‐based alloys are promising candidates for temporary implants, yet excessive Zn2+ release during degradation may induce cytotoxicity and adverse tissue responses. In this study, Zn‐xBa alloys (x = 0.1 wt%, 0.5 wt%, 1.0 wt% and 3.0 wt%) were developed to achieve controlled corrosion behaviors with improved biocompatibility.
Liu‐Dang Fang +9 more
wiley +1 more source
“百毒杀”消毒剂在动物园中的应用张恩珠,车桂翠,贲亚华(齐齐哈尔龙沙公园161005)百毒杀做为优秀的消毒剂,其特点是杀灭细菌病毒迅速,作用时间长。在正确比例浓度应用时其毒性、刺激性、腐蚀性和蓄积性都小于目前其它类消毒剂。现国内外已广泛应用,但在野生...
张恩珠, 车桂翠, 贲亚华
doaj
Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang +6 more
wiley +1 more source

