Results 151 to 160 of about 25,302 (204)

[Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair]. [PDF]

open access: yesZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu F   +5 more
europepmc   +1 more source

番茄红素对脂多糖诱导巨噬细胞炎症反应的作用及其分子机制

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 探讨番茄红素对脂多糖(LPS)所诱导的RAW264.7巨噬细胞炎症因子生成的影响及其作用的分子机制【方法】 分别用1510 μmol/L 的番茄红素孵育细胞1 h,再用1 μg/mL LPS 处理细胞不同时间,分别用Griess法和ELISA法检测RAW264.7巨噬细胞培养基中NO及IL-6的含量,用Western-blot检测核因子-κB(NF-κB) p65磷酸化和非磷酸化I-κBα丝裂原活化蛋白激酶(MAPKs)的蛋白表达量【结果】 番茄红素能有效地降低炎性因子NO和IL-6分泌 ...
doaj  

[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Zhao RQ   +9 more
europepmc   +1 more source

[Advances in application of hydrogels for treatment of osteonecrosis of the femoral head]. [PDF]

open access: yesZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Han G, Li Q, Wang Q, Kang P.
europepmc   +1 more source

PGC-1α通过上调SIRT3表达发挥心肌保护作用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】探讨第III类组蛋白去乙酰化酶成员3(SIRT3)在过氧化物酶体增殖物受体γ共激活因子1α(PGC-1α)的调控下发挥改善心肌肥大和心肌能量代谢的作用?【方法】 建立血管紧张素II(Ang II)诱导的心肌肥大模型;利用质粒转染诱导PGC-1α基因过表达?siRNA干扰敲低SIRT3表达;Western blot检测PGC-1α?SIRT3及心肌肥大标志蛋白肌球蛋白重链β(β-MHC)的水平?TMRE染色法测定线粒体膜电位;测定ATP含量;DHE染色法测定活性氧水平;qRT ...
doaj  

[cGAS-STING agonist cGAMP enhances natural killer cell-mediated cytotoxicity against gastric cancer cells]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
Wang Q   +6 more
europepmc   +1 more source

[Spatial omics in pulmonary fibrosis: advancing mechanistic insights and therapeutic strategies]. [PDF]

open access: yesZhejiang Da Xue Xue Bao Yi Xue Ban
Peng Y, Xie Y, Yang F, Qiao X, Tian Y.
europepmc   +1 more source

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