Results 161 to 170 of about 22,800 (217)

番茄红素对脂多糖诱导巨噬细胞炎症反应的作用及其分子机制

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 探讨番茄红素对脂多糖(LPS)所诱导的RAW264.7巨噬细胞炎症因子生成的影响及其作用的分子机制【方法】 分别用1510 μmol/L 的番茄红素孵育细胞1 h,再用1 μg/mL LPS 处理细胞不同时间,分别用Griess法和ELISA法检测RAW264.7巨噬细胞培养基中NO及IL-6的含量,用Western-blot检测核因子-κB(NF-κB) p65磷酸化和非磷酸化I-κBα丝裂原活化蛋白激酶(MAPKs)的蛋白表达量【结果】 番茄红素能有效地降低炎性因子NO和IL-6分泌 ...
doaj  

Mitigating light pollution impacts on arthropods based on light‐emitting diode properties

open access: yesConservation Biology, Volume 40, Issue 1, February 2026.
Abstract Light pollution from artificial light at night (ALAN) is a significant environmental problem with far‐reaching consequences for ecological systems. Recent innovations in light‐emitting diode (LED) technology may offer sustainable outdoor lighting solutions, but scientific evidence is lacking. We investigated the effects of various LED lighting
Nicola van Koppenhagen   +3 more
wiley   +1 more source

PGC-1α通过上调SIRT3表达发挥心肌保护作用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】探讨第III类组蛋白去乙酰化酶成员3(SIRT3)在过氧化物酶体增殖物受体γ共激活因子1α(PGC-1α)的调控下发挥改善心肌肥大和心肌能量代谢的作用?【方法】 建立血管紧张素II(Ang II)诱导的心肌肥大模型;利用质粒转染诱导PGC-1α基因过表达?siRNA干扰敲低SIRT3表达;Western blot检测PGC-1α?SIRT3及心肌肥大标志蛋白肌球蛋白重链β(β-MHC)的水平?TMRE染色法测定线粒体膜电位;测定ATP含量;DHE染色法测定活性氧水平;qRT ...
doaj  

Evidence for a fisher‐designed solution to manta and devil ray bycatch in tuna fisheries

open access: yesConservation Biology, Volume 40, Issue 1, February 2026.
Abstract Bycatch in global tropical tuna purse seine fisheries represents a significant source of mortality for manta and devil rays (mobulids), which are globally threatened. Use of best handling and rapid release practices on purse seine vessels can substantially reduce mortality and improve vulnerability status for mobulids.
Melissa R. Cronin   +12 more
wiley   +1 more source

Informal Digital Learning of English (IDLE) as Form‐Focused and Meaning‐Focused Activities: Refining its Measurement and Examining its Predictive Role in L2 Achievement and Confidence

open access: yesInternational Journal of Applied Linguistics, Volume 36, Issue 1, Page 393-408, February 2026.
ABSTRACT Acknowledging the limitations of existing measurement instruments in adequately capturing the distinct cognitive processes (e.g., form‐focused vs. meaning‐focused) involved in informal digital learning of English (IDLE), this paper asserts a pressing need to develop and validate robust instruments that measure form‐focused and meaning‐focused ...
Minlin Zou   +3 more
wiley   +1 more source

Metadiscourse and Teacher Moves for Supporting Student Reasoning in Linguistics Classroom Interactions

open access: yesInternational Journal of Applied Linguistics, Volume 36, Issue 1, Page 522-539, February 2026.
ABSTRACT This paper examines the features of metadiscourse across different teacher moves in university linguistics classroom discourse and the teaching strategies reflected in its use. The results reveal that teachers employ diverse metadiscourse during classroom interactions to support student reasoning.
Jingjie Li, Wenjie Hu
wiley   +1 more source

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