【目的】 对两株从轻症病例和重症死亡病例中分离的人H7N9禽流感病毒进行全基因组测序,研究其来源?基因组特征以及相互间的分子差异,旨在了解毒株的遗传进化特征与其致病性及其所致疾病临床类型的关系,为进一步阐明H7N9禽流感病毒的致病机制提供科学依据?【方法】 选取两株从轻症病例和重症死亡病例中分离的H7N9禽流感病毒进行全基因组序列测定;运用生物信息学软件比较分析两株病毒的遗传进化关系?基因组特征?受体结合位点?宿主特异性位点及致病相关位点等重要分子特征;从禽流感共享数据(GISAID ...
doaj
[Epidemiological characteristics of febrile seizure among children under 6 years old in Ningbo City from 2015 to 2021]. [PDF]
Liu G +10 more
europepmc +1 more source
【目的】探讨糖尿病大鼠视网膜中央动脉(CRA)的血流动力学变化及灯盏花素的防治作用。【方法】用链脲佐菌素(STZ)诱导糖尿病模型后,在第12-13周采用彩色多谱勒对各组视网膜中央动脉(CRA)进行血流参数的测量,包括峰值血流速度(PSV)、舒张期最低流速(EDV)、平均血流速度(MV)、阻力指数(RI)和搏动指数(PI)。【结果】糖尿病组大鼠CRA的血流速度较对照组显著降低 ...
doaj
[Epidemiological characteristics of hemorrhoids in a healthy physical examination population in China]. [PDF]
Guo C +10 more
europepmc +1 more source
Epidemiology and pathogenesis of the link between rheumatoid arthritis and periodontitis. [PDF]
Fang H, Lin J, Qiu Y, Cheng Z, Chen W.
europepmc +1 more source
Augmented renal clearance in neurocritical patients: An epidemiological investigation and risk-factor analysis. [PDF]
Xiao Q, Luo B, Zhang H, Wu X.
europepmc +1 more source
Antibiotic resistance and epidemiological characteristics of polymyxin-resistant Klebsiella pneumoniae. [PDF]
Chen L +7 more
europepmc +1 more source
[Epidemiology of atrial fibrillation/atrial flutter and its risk factors from 1990 to 2021: a systematic analysis and Mendelian randomization study based on the China and Global Burden of Disease Study 2021]. [PDF]
Ma H, Yan K, Liu G, Xu Y, Zhang L, Li Y.
europepmc +1 more source

