Results 21 to 30 of about 18,233 (162)
Veterinary Dermatology, Volume 36, Issue 5, Page 552-565, October 2025.Abstract Background Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler +9 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2017 糖尿病是一种全球性公共卫生挑战。在最近的国际糖尿病联盟发布的糖尿病地图中报告,世界上糖尿病患者流行人数估计达8.3%,约3.87亿,每7秒就有一人因糖尿病死亡[1]。2013年中华医学会糖尿病学分会公布糖尿病流行病学调查结果显示,我国18岁以上人群糖尿病患病率为9.
顾天菊, 王清
doaj
The establishment of Elispot-based neutralization assay for HCMV and its application in epidemiological study [PDF]
, 2013 人巨细胞病毒（humancytomegalovirus，HCMV）的感染在全球普遍存在。HCMV感染一般以潜伏状态存在，当机体免疫力低下时，则易发生再激发感染，引起严重甚至威胁生命的感染性疾病。在自然感染过程中，HCMV可感染包括淋巴细胞，上皮细胞以及内皮细胞在内的多种类型的细胞。HCMV体外培养体系的宿主细胞主要是上皮细胞及成纤维细胞。传统的基于细胞病变的TCID50以及空斑形成减少实验检测样本中和滴度的方法，存在周期长，操作繁杂，主观因素影响大的缺点，不适合大样本量的临床研究 ...
赵利利
core
Infant Mental Health Journal: Infancy and Early Childhood, Volume 46, Issue 5, Page 564-576, September 2025.Abstract Parental reflective functioning (PRF) is important in guiding parenting behavior. It is traditionally measured with interviews that are relatively time‐consuming. A self‐report measure of PRF, the Parental Reflective Functioning Questionnaire (PRFQ), has been developed but has not yet been extensively validated across different sociocultural ...
Marjo Flykt +4 more
wiley +1 more source
Anatomic and radiograph study of anterior cruciate ligament reconstruction [PDF]
, 2015 目的：1、观察膝关节交叉韧带股骨附着处的解剖形态学特点，并利用PhotoshopCC2014软件测量股骨附着处印迹的实际面积大小；2、研究标准膝关节侧位X线片上前交叉韧带（ACL）股骨止点的相关骨性标志数据，为临床上ACL双束解剖重建提供参考。 方法：对10例成人膝关节标本进行解剖，剔除膝关节标本周围肌肉、关节囊，把髌韧带从股骨端切断，保留髌骨、髌韧带、内外侧副韧带、前后交叉韧带及内外侧半月板，经髁间窝前出口最高点沿矢状面在股骨前面和后面作两条平行股骨纵轴的直线，用手锯沿两直线将股骨分为两部分 ...
甘志勇
core
Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective
World Medical &Health Policy, Volume 17, Issue 3, Page 468-474, September 2025.ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2023 目的 了解长春市儿童下呼吸感染病原学特征及其分布规律，为本地区儿童下呼吸道感染的临床治疗提供的参考依据。方法 采用Realtime PCR方法对2018年12月至2019年11月份采集的73份儿童支气管肺泡灌洗液标本进行28种病原及亚型检测。结果 儿童下呼吸道感染中非典型病原体以支原体为主，病毒病原以呼吸道腺病毒、EB病毒、副流感病毒以主，细菌病原感染以流感嗜血杆菌为主。不同的病原体表现不同的流行期。结论 通过对长春市儿童下呼吸道感染进行多病原检测，掌握病原流行特点，不同季节的呼吸道病原谱不一致。
李静 +4 more
doaj
Cyclin Dependent Kinase 5 promotes invasion and metastasis of Hepatocellular Carcinoma [PDF]
, 2016 肝细胞癌（HepatocellularCarcinoma，HCC）在所有恶性肿瘤导致的死亡原因中占第三位，其发病率居恶性肿瘤的第六位。肝癌具有的高复发以及高转移，使肝癌愈后很差，而导致肝癌高复发和高转移的机制还不是很清楚。最近研究表明细胞周期蛋白激酶家族蛋白在上述调控过程中具有重要作用。 细胞周期素依赖蛋白激酶家族中的一个特殊蛋白：细胞周期素依赖蛋白激酶5（CyclinDependentKinase5，CDK5）引起了我们的注意，CDK5被认为主要在神经系统发挥作用。但是 ...
赵文兴
core
Review of Policy Research, Volume 42, Issue 5, Page 1322-1349, September 2025.Abstract Narratives play an essential role in fast‐paced policy making that occurs during crises. The COVID‐19 pandemic brought numerous disruptions of normality, including school closures, which were intensely debated in narratives by many policy actors. Two shutdowns of New York City's public school system affected over 1.1 million students.
Nikolina Klatt, Sonja Blum
wiley +1 more source
The expression and clinical significance of SATB2 in Esophageal Squamous Cell Carcinoma [PDF]
, 2015 摘要 研究目的：食管癌在中国是一种高发的消化系统恶性肿瘤。由于解剖位置深、临床症状隐匿、早期症状不明显、易以多种路径转移、高位癌手术残留、术后容易复发以及放化疗不敏感等特点，食管癌预后较差。因此，进一步深入研究食管癌发生发展、侵袭转移以及预后评估因素的内在机制具有重要的意义。SATB1是富含AT序列结合蛋白的特殊家庭成员之一，已被证明影响众多肿瘤致瘤性的过程。SATB2与肿瘤的关系密切一直是研究的关注点，然而，其在食管鳞状细胞癌组织中的作用不清楚。本论文以食管鳞癌为研究对象，以SATB2为切入点 ...
李宁
core