Results 121 to 130 of about 10,123 (212)

O2‐Accessible Fe–N4 Active Site Density Boosts Efficient Oxygen Reduction to Fuel‐Cell Level

open access: yesAdvanced Materials, Volume 38, Issue 16, 17 March 2026.
This study investigates the role of hierarchical nanostructure design in optimizing oxygen mass transport for the oxygen reduction. Using atomically dispersed Fe–N–C catalysts with solid, yolk‐shell, and hollow structures, it demonstrates that the yolk‐shell architecture provides superior O2 accessibility to active Fe–N4 sites.
Tianyu Zhang   +7 more
wiley   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen   +11 more
wiley   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu   +6 more
wiley   +1 more source

A research on the environmental evaluation index system of provincial capitals ——Based on the Fuzhou City [PDF]

open access: yes, 2016
2012年,党中央将生态文明提升到与政治、经济、社会、文化相同的高度,提出要建设美丽中国。环境保护由此进入一个新的战略阶段。环境绩效评估的有效实施,可以识别环境现状和环境目标之间的差距,判断环境政策在实施过程中的成效与不足,为各级行政管理部门制定环境政策提供科学依据和数据支撑。 本文以省会城市福州市为例,总结多年来福州市环境绩效评估的相关指标体系,探索构建基于城市定位及环境战略分区,符合区域环境现状、经济社会发展情况及环境功能定位的环境绩效评估指标体系,为明确区域环境保护重点领域,改善区域环境功能 ...
陈杨炀
core  

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia   +14 more
wiley   +1 more source

Design and Implementation of the Teacher Digital Work Platform for Primary School [PDF]

open access: yes, 2016
某小学是一所公办普通小学,主要负责培养九年义务教育阶段的学生,是浙江省一流的标准化普通小学,全面贯彻党中央国务院的教育方针政策,积极办学,积极推进素质教育,努力培养个性特长,创造条件,营造环境,全面推进教师课程改革和学生全面发展。互联网信息技术的快速变革为教育信息化建设提供了有力的帮助,数字化工作平台建设能够对传统的教育模式进行有益拓宽,丰富和延伸教师教学、学生学习的活动和视野,为教学活动的多元化提供服务。 某小学教师数字化工作平台建设项目基于Web方式进行开发,采用成熟的三层体系架构,实现了用户管理 ...
王笑笑
core  

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu   +6 more
wiley   +1 more source

Clinical characteristics and plasma antibody titer of patients with COVID-19 in Zhejiang, China. [PDF]

open access: yesJ Zhejiang Univ Sci B, 2020
Xiang WL   +9 more
europepmc   +1 more source

彙報 [PDF]

open access: yes, 2017
文部科学省グローバルCOEプログラム ...

core   +1 more source

Mathematical Prediction for Geometry‐Mediated Cell 3D In‐Growth on Bone Tissue Engineering Scaffolds

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
This study identifies a fundamental pore size dependent pattern of three dimensional bone marrow derived mesenchymal stem cell (BMSC) infiltration within porous scaffolds, where small pores promote horizontal cellular bridging and large pores facilitate vertical migration.
Xiang Gao   +15 more
wiley   +1 more source

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