The left panel shows cerebral lactate homeostasis in young mice. The middle panel displays accelerated ANLS rates due to FGF21 secretion in aging mice. The right panel demonstrates that lactate uptake and usage inhibition contribute to lactate extracellular accumulation, followed by HCA1‐mediated learning and memory decline in mice.
Keru Ji +6 more
wiley +1 more source
[Association between dynamic elevation of high-sensitivity cardiac troponin T and functional outcomes in patients with acute ischemic stroke]. [PDF]
Xi Z +9 more
europepmc +1 more source
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source
[Comparison of functional outcomes between tenecteplase and alteplase as bridging thrombolysis prior to mechanical throm-bectomy for acute ischemic stroke patients with large vessel occlusion]. [PDF]
Shi Z +8 more
europepmc +1 more source
[Semi-quantitative risk assessment of human infection with H7N9 avian influenza epidemic in Zhejiang province]. [PDF]
Yang T, Li F, He F.
europepmc +1 more source
ABSTRACT Dent's disease, an X‐linked recessive disorder predominantly affecting males, is characterized by nephrocalcinosis, nephrolithiasis, and a high risk of progression to end‐stage renal disease. Dent's disease type 1, accounting for 60% of cases, caused by mutations in the CLCN5 gene encoding the chloride ion channel protein ClC‐5, exhibits ...
Chengpeng Wu +8 more
wiley +1 more source
[Efficacy and safety of mechanical thrombectomy beyond 24 to 72 hours in acute ischemic stroke patients with large vessel occlusion]. [PDF]
Jiang X +8 more
europepmc +1 more source
GmMYB4 Positively Regulates Isoflavone Biosynthesis via the GmMAPK6‐GmMYB4‐MBW Module in Soybean
ABSTRACT Isoflavones, a class of bioactive compounds predominantly found in leguminous plants, are largely responsible for their beneficial effects on human health. Although MYB transcription factors (TFs) are known to be crucial regulators of isoflavone biosynthesis in soybean, the precise mechanisms underlying their regulatory functions remain poorly
Changyun Yang +12 more
wiley +1 more source
根据浙江省农用地的实际特点,在GIS技术的支持下,探索农用地分等因素因子作用分值图的编制及其应用、农用地分等单元的划分方法,以及土地质量综合分值的测算,紧密结合农作物的气候生产潜力,提出气候生产潜力-总分值的复合分等指数。依据修正后的分等指数,将浙江省农用地划分为20个等别。
doaj
[Clinical value of AI-assisted cardiac auscultation in screening for congenital heart disease in neonates]. [PDF]
Zhang J +5 more
europepmc +1 more source

