Results 161 to 170 of about 47,871 (257)
ABSTRACT Objective Irinotecan, a standard therapeutic agent for metastatic colorectal cancer (mCRC), often faces significant limitations due to drug resistance, with treatment failure observed in approximately 30%–50% of patients, leading to poor clinical outcomes.
Yi Pan +9 more
wiley +1 more source
[Impact of outpatient services utilization of heart failure patients on hospitalization rate and its threshold effect: Taking patients with Urban Employee Basic Medical Insurance in Zhejiang Province as an example]. [PDF]
Zhang H, Jing R, Wang J, Fang H.
europepmc +1 more source
Integrative Omics Analysis Reveals the Potential Value of CEACAM6 in Pan‐Gastrointestinal Cancers
Expression of CEACAM6 in spatial transcriptomic of colorectal cancer with liver metastases. (A) Predicted cell types mapping on colorectal cancer tissue slice; (B) Spatial distribution of CEACAM6; (C) Spatial distribution of malignant region, mixed region and normal region; (D) The difference expression of CEACAM6 in malignant region, mixed region and ...
Liying Jin +3 more
wiley +1 more source
[Association between factors in life course and physiological dysregulation among the middle-aged and older population in Zhoushan city of Zhejiang province]. [PDF]
Cao X +9 more
europepmc +1 more source
ABSTRACT Background Sarcopenia is an age‐related degenerative disorder characterized by a progressive decline in skeletal muscle mass, strength, and function with high prevalence in chronic kidney disease (CKD). Identifying clinical and epidemiological factors of sarcopenia in patients with CKD is essential to enable early recognition and appropriate ...
Kaili Jin +6 more
wiley +1 more source
[Analysis and summary of clinical characteristics of 289 patients with paroxysmal nocturnal hemoglobinuria in Zhejiang Province]. [PDF]
Xu GX +25 more
europepmc +1 more source
Engineered Bacteroides fragilis outer membrane vesicles carrying anti‐IL‐1β scFv and kidney‐targeting peptides alleviate renal inflammation and injury in CKD mouse models via precise delivery and NF‐κB inhibition. ABSTRACT Microinflammation is a key driver of chronic kidney disease (CKD) progression, with interleukin‐1β (IL‐1β) playing a pivotal role ...
Liang Li +6 more
wiley +1 more source

