Results 11 to 20 of about 1,470 (101)

不同类型淋巴瘤组织中EB病毒的表达及意义

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 检测100例淋巴瘤患者中潜伏膜蛋白1(LMP1)及EBV编码的小RNA(EBER)的表达情况;观察LMP1与EBER的相关性及二者与淋巴瘤类型的相关性,为淋巴瘤的诊断提供依据。方法 采用免疫组化SP法和原位杂交法分别检测100例淋巴瘤患者中LMP1和EBER的表达情况,比较两种方法的敏感性。结果 (1)仅经典型霍奇金淋巴瘤、弥漫性大B细胞淋巴瘤表达LMP1和EBER及NK/T细胞淋巴瘤表达EBER,其余类型淋巴瘤中非肿瘤细胞可散在表达EBER ...
徐海芹   +3 more
doaj  

Clinicopathological analysis of DLBCL/HGBL with MYC, BCL2 and BCL6 gene rearrangement [PDF]

open access: yes, 2023
Background and purpose: Diffuse large B-cell lymphoma/high-grade B-cell lymphoma (DLBCL/HGBL) with gene rearrangement of MYC, BCL2 and BCL6, also known as triple-hit lymphoma (THL), has a low incidence and relevant literature is limited.
WEI Jing, HE Yaqi, XUE Tian, BAI Qianming, SHUI Ruohong, LU Hongfen, LI Xiaoqiu, YU Baohua
core   +1 more source

A qualitative study on the establishment and application experience of whole-process management nursing pathway for lymphoma patients by navigation nurses (导航护士对淋巴瘤患者全程管理护理路径建立及应用体验的质性研究)

open access: yes中西医结合护理
Objective To understand the establishment and application experience of whole-course management nursing path for lymphoma patients by navigation nurses, and to provide reference for the construction of whole-course management for lymphoma patients ...
WANG Shijuan (王石娟)   +6 more
doaj   +1 more source

B cell lymphoma:Characterization of the microenvironment and the tumor cell proteome [PDF]

open access: yes, 2016
B cell lymphoma is the most common hematologic malignancy. Besides alterations in the malignant lymphoma cells, also the interaction with the microenvironment has gained much interest in recent years.
Wu, Rui
core   +2 more sources

Efficacy of Lithospermum oil gauze wet compress in preventing and treatment of mechanical phlebitis after PICC catheters placement in patients with malignant lymphoma (紫草油纱湿敷防治恶性淋巴瘤患者PICC置管机械性静脉炎的效果观察)

open access: yes中西医结合护理
Objective To investigate the efficacy of Lithospermum oil gauze wet compress in preventing and treatment of mechanical phlebitis caused by peripherally inserted central catheter(PICC) catheters placement in patients with malignant lymphoma.
WANG Shijuan (王石娟)   +5 more
doaj   +1 more source

Cutaneous epitheliotropic T‐cell lymphoma in a sugar glider (Petaurus breviceps)

open access: yesVeterinary Dermatology, Volume 36, Issue 2, Page 218-221, April 2025.
A 3‐year‐old male sugar glider presented with pruritus and alopecia primarily affecting the back and neck regions. Dermatologic diagnostics ruled out common causes. Skin biopsies revealed cutaneous epitheliotropic T‐cell lymphoma, a rare condition in sugar gliders. Despite treatment, the glider's condition worsened, leading to death.
Piercarlo Amati   +3 more
wiley   +1 more source

Novel CRM1 Inhibitor Induces Beclin-1 Signaling Mediated Autophagy in Mantle Cell Lymphoma [PDF]

open access: yes, 2015
摘要 目的:探讨新型CRM1抑制剂对套细胞淋巴瘤(MCL)细胞自噬的影响和机制。 方法:应用CCK8法检测新型CRM1抑制剂KPT-185对8株MCL细胞的增殖抑制作用、KPT-185联合蛋白酶体抑制剂Carfilzomib(CFZ)对JVM2和JEKO-1细胞的增殖抑制作用,并用CalcuSyn软件分析KPT-185与CFZ的联合用药指数(Combinationindex,CI);不同浓度的KPT-185作用于JEKO-1和Z-138细胞后不同时间,采用MDC荧光染色 ...
陈昱函
core  

A multicentric intermediate‐size B‐cell lymphoma with epitheliotropism in a Freiberger mare

open access: yesVeterinary Dermatology, Volume 35, Issue 5, Page 573-577, October 2024.
This report describes a multicentric intermediate‐size B‐cell lymphoma with epitheliotropism in a Freiberger mare affecting multiple mucous membranes, skin and internal organs. The clonal neoplastic B‐cell population was accompanied by numerous reactive polyclonal small T cells. Differential diagnoses for these unusual findings are discussed.
Inês Berenguer Veiga   +6 more
wiley   +1 more source

Construction and preliminary application of human naïve phage antibody library [PDF]

open access: yes, 2004
治疗性抗体在临床的应用已从30年代的抗血清时代经由80年代后的单克隆抗体时代进入到今天的基因工程抗体时代。目前处于各期临床的生物新药中,基因工程抗体是最多的一类,显示出治疗性抗体具有广阔的临床应用前景,而人源抗体是治疗性抗体的发展趋势。人源性噬菌体抗体库技术解决了人源性单抗来源困难、人体杂交瘤系统低效及鼠单抗的动物源性难题,是分子生物学和免疫学领域中一个强有力的研究手段。本研究从20例未经免疫的健康人的外周血中分离出淋巴细胞,提取总RNA并纯化出mRNA,然后反转录成cDNA ...
李利峰
core  

Immunosuppression complicated with Legionnaires’ disease after chemotherapy in a lymphoma patient confirmed by blood mNGS: one case report and literature review [PDF]

open access: yes, 2023
Objective To analyze the clinical characteristics of Legionnaires’ disease in immunosuppressive patients, and to explore the significance of blood metagenomic next-generation sequencing (mNGS) in the early diagnosis and treatment of Legionnaires’ disease
Zhou Lei, Zhu Wenwen
core   +1 more source

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