Results 1 to 10 of about 2,081 (138)

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang   +11 more
wiley   +1 more source

Orifice barriers to prevent coronal microleakage after root canal treatment: systematic review and meta‐analysis

open access: yesAustralian Dental Journal, Volume 68, Issue 2, Page 78-91, June 2023., 2023
ABSTRACT Aims This systematic review aimed to compare the efficiency of orifice barriers in preventing coronal microleakage in vitro. Methods Articles published in English, German and Chinese were searched for studies describing microleakage assays for the bacterial penetration of root canal‐treated teeth in vitro. The final sample included 18 articles
P Chen   +4 more
wiley   +1 more source

Percutaneous fetoscopic spina bifida repair: effect on ambulation and need for postnatal cerebrospinal fluid diversion and bladder catheterization

open access: yesUltrasound in Obstetrics &Gynecology, Volume 58, Issue 4, Page 582-589, October 2021., 2021
Abstract Objective A trial comparing prenatal with postnatal open spina bifida (OSB) repair established that prenatal surgery was associated with better postnatal outcome. However, in the trial, fetal surgery was carried out through hysterotomy. Minimally invasive approaches are being developed to mitigate the risks of open maternal–fetal surgery.
D. A. Lapa   +9 more
wiley   +1 more source

Blockchain and Quantum Technologies for Securing the Global Nuclear Supply Chain: Synergies, Applications, Technical Challenges and Opportunities

open access: yesJournal of Critical Infrastructure Policy, Volume 7, Issue 1, Spring/Summer 2026.
ABSTRACT The infiltration of counterfeit, fraudulent, and suspect items into civil nuclear supply chains, notably within power generation and medical isotope production, poses severe safety and security threats. The ever‐increasing growth in nuclear installations (70 power plants are under construction and another 100 are in the planning stage) and the
Hafiz Ahmed
wiley   +1 more source

桂西北喀斯特地区新开水田渗漏特征与效益

open access: yesShuitu Baochi Xuebao, 2006
在桂西北喀斯特地区,新开水田经营4年后渗漏系数是老田的1.36~1.45倍,漏水漏肥仍很严重,经营成本增加,增加经营中的犁耙次数,可以加速犁底层的形成,减少渗漏。从投入产出来讲,新开水田前2年种植旱作(大豆或早稻),第3年开始种植水稻,既能有效降低新开田的渗漏,又能减少经营成本,获得较好的经济效益。
曾馥平
doaj   +2 more sources

The Application of Long Circulation Liposomes Combined with Phospholipid Complex or Calcium Phosphate Coated- Mesoporous Silica in Anti-Tumor Therapy [PDF]

open access: yes, 2016
纳米药物传递系统种类多样,优势明显。良好的纳米药物传递系统能够降低药物的毒副作用,延长药物在体循环时间,缓控释药物以及拥有良好的靶向性能等特点,使得其具有更好的疗效和治疗指数。然而在抗癌药物载体的研究中,许多药物传递系统的细胞摄取效果并不佳,若长循环脂质体运用在纳米药物传递系统中,势必能够增加药物载体的生物相容性,延长药物在体循环时间。 本课题研究了长循环脂质体在“软物质”和“硬颗粒”两种模型纳米药物载体中的应用,分别对其形态、粒径、电位等理化性质进行了表征,对其稳定性、细胞毒性 ...
吴泓杰
core  

土壤大孔隙形态对喀斯特区水土漏失过程的影响

open access: yesShuitu Baochi Xuebao, 2020
在岩溶作用下,喀斯特土壤—表层岩溶带耦合发育,上覆土壤中大孔隙与下伏表层岩溶带中裂隙、管道存在密切的水力联系,然而土壤大孔隙影响土壤—表层岩溶带系统中水土漏失的过程机理尚不清楚。通过人工模拟降雨试验,采用试验微区模拟不同土壤大孔隙形态(出露型、浅埋型、深埋型),并以全土微区为对照,探讨了土壤大孔隙对喀斯特地区水土漏失过程的影响。结果表明:与全土微区相比,土壤大孔隙的存在明显加速了水分的垂直渗漏,其对水分渗漏量的影响表现在峰值不同(出露型 > 浅埋型 > 深埋型 > 全土 ...
周春衡   +4 more
doaj  

An experimental study about the restrictive fluid resuscitation for burns shock [PDF]

open access: yes, 2015
研究目的 本研究通过颈内静脉置管大鼠烫伤休克模型,探讨限制性液体复苏在烧伤休克救治中的应用的可行性,为临床采用限制性液体复苏方案提供实验理论依据。 研究方法 将60只Wistar雄性大鼠按随机数字表法分成对照组、单纯颈内静脉置管组(单纯组)、实验1组、实验2组、实验3组、实验4组,每组10只。单纯颈内静脉置管组和实验1、2、3、4组均进行颈内静脉置管术,对照组颈部不做处理;所有大鼠均进行背部及双侧脱毛,术后大鼠单笼饲养1天;次日,实验1、2、3、4组大鼠麻醉后背部、双侧浸于100˚ ...
段训洪
core  

The synthesis and investigation of Silica/Lipid related nanohybrid for anti-cancer drug delivery [PDF]

open access: yes, 2015
化学治疗法是肿瘤学中最广泛应用的方法,但传统的化疗药给药方式存在靶向性低,毒副作用大,容易出现肿瘤耐药性等多重障碍,严重影响了癌症的治疗。现如今,随着纳米科技的发展,设计出一种纳米载药系统应用于化疗药物的传递,从而降低给药剂量、降低毒副作用、提高细胞吸收具有明显的临床意义。在诸多纳米粒材料的选择中,硅纳米粒由于其具有诸多良好的物理化学性质被广泛应用于药物传递及生物成像,然而普通二氧化硅纳米粒性质较为单一且载药量较小;介孔二氧化硅药物容易渗漏,靶向释放性能较差,这些都限制了二氧化硅纳米粒的进一步发展和应用。
刘泽华
core  

用大型Lysimeter和TDR测算赣东北红壤农田的渗漏量

open access: yesShuitu Baochi Xuebao, 2002
红壤农田的渗漏量及透水性能对评价红壤水土流失状况具有很重要的意义。利用大型称重式蒸渗仪、时域反射仪和张力计 ,研究了赣东北红壤农田的渗漏量。结果表明 ,红壤农田土体渗漏性能良好 ,4 0 0 cm处最高日渗漏量可达 6 0 mm / d;3年结果表明年渗漏量为 10 36 .37~ 16 2 0 .4 6 mm,占到年降水量的 5 5 .1%~ 6 7.0 % ;在有花生生长和等高种植的情况下 ,即使在雨季 ,缓坡农田的径流量也很小而渗漏量较大。红壤表层以下的透水状况不是造成土壤侵蚀的主要因素 ...
陈家宙 何圆球 陈明亮
doaj  

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