Results 31 to 40 of about 19,759 (205)
Affinity Maturation of Human Immunodeficiency Virus Diagnostic Antibody [PDF]
, 2012 9E8是本实验室筛选获得的一株针对人类免疫缺陷病毒（HumanImmunodeficiencyVirus，HIV）的鼠源抗体，其亲和力为3.23×10-10M，目前已经成功应用到本实验室开发的HIV诊断试剂盒中，但其灵敏度和特异性都还有待提高。 本研究的目的就是利用噬菌体展示技术对HIV诊断抗体9E8进行亲和力成熟，进一步提高HIV诊断的灵敏度和特异性。首先，用RT-PCR的方法从杂交瘤细胞中调取鼠源抗体9E8的可变区基因，将其构建成单链抗体VH-(G4S)3-VL的形式，展示到噬菌体pIII蛋白上 ...
李善伟
core
Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 6, Page 768-775, December 2024.Abstract Objective Lower urinary tract obstruction (LUTO) is a chronic condition with a spectrum of outcomes. It is usually suspected prenatally based on ultrasound features (USFs). Given the unknown postnatal trajectory and the potential for significant morbidity and mortality, many families choose termination of pregnancy (TOP), often based on USFs ...
J. Richter +10 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 目的利用结核分支杆菌噬菌体裂解法检测结核杆菌对利福平、异烟肼、链霉素敏感性。方法选用传统方法判定为利福平、异烟肼、链霉素的耐药或敏感菌株,采用噬菌体裂解法检测其对以上三种药物的敏感性,对比其特异性和敏感度。结果运用噬菌体裂解法检测结果显示,异烟肼药物浓度为1μg/ml时,其灵敏度为87.0%,特异度为93.3%,与传统方法的符合率为92.0%;链霉素药物浓度为4μg/ml时,其灵敏度为96.2%,特异度为92.0%,与传统方法的符合率为92.9%;利福平药物浓度为5μg/ml时,其灵敏度为91.4 ...
于宏波, 宋阳, 齐红, 韩忠波
doaj
Guangtongxin yanjiu, 2020 针对光纤布拉格光栅（FBG）超声探测传感器测量灵敏度和量程相互制约的问题,文章提出了一种基于法布里珀罗（FP）腔和π相移FBG（π-FBG）的解调方案。文章分析了利用FP腔解调的原理并进行了详细的数值仿真分析。理论分析表明,利用FP腔的两个纵模作为一组解调器同时解调,可将系统灵敏度提高两倍,并且具有很好的线性度。扩展到多个纵模时可构建解调器阵列,从而极大地提高了系统的量程,有效地解决了测量灵敏度和量程相互制约的问题。数值仿真结果表明,该方案在实际可操作参数范围内切实可行,并具有灵敏度高和响应速度快等优势。
高在青 +3 more
doaj
Greenhouse gas emissions from croplands of China [PDF]
, 2003 China possesses cropland of 1.33 million km 2. Cultivation of the cropland not only altered the biogeochemical cycles of carbon (C) and nitrogen (N) in the agroecosystems but also affected global climate.
Bohan, Liao +13 more
core +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 661-668, November 2024.ABSTRACT Objective To determine the diagnostic accuracy of virtual autopsy using whole‐body postmortem ultra‐high field magnetic resonance imaging (MRI) at 7 Tesla (T), using a short T2‐weighted imaging (T2‐WI) protocol, compared with classical autopsy, for detecting structural abnormalities in small second‐trimester fetuses. Methods Thirty consecutive
A. Staicu +11 more
wiley +1 more source
Guangtongxin yanjiu, 2005 结合IEEE 802.3 ah标准中的以太无源光网络（EPON）接收灵敏度指标,着重分析了接收灵敏度光调制幅度（OMA）,该OMA指标的采用有利于系统降低对消光比的要求,使发射机和接收机的设计更加简单;最后,简要讨论了OMA和增强型接收灵敏度的测试,指出增强型测试更有实际意义。
杨立伟, 寿国础
doaj
Gaoya dianqi, 2021 传统SMS结构的光纤传感器具有模式单一、损耗较大的问题而导致温度灵敏度较低,文中采用单模—多模—多模—多模—单模结构的新型光纤马赫—曾德尔干涉传感器,对原有结构进行了改进。大芯径多模光纤与两端的单模光纤耦合,实现光的分束和合束,同时将大芯径多模光纤与小芯径多模光纤（MMF2）熔接,使高阶模与基模分别进入小芯径多模光纤包层与纤芯进行传输从而产生相位差,最终形成对温度敏感的模式干涉,理论分析了该结构的温度敏感特性。采用MMF2长度分别为8 mm和12 mm的两种该结构传感器,温度灵敏度均能提高到80 pm/℃
皎文毓, 肖玉阳, 孙雨欣
doaj
Design, synthesis and preliminary bio-evaluation of progestrone receptor targeting probes for breast cancer imaging with PET [PDF]
, 2016 乳腺癌是严重威胁女性健康的疾病，它的早期诊断能够有效的降低病人的死亡率。孕激素受体属于核受体超家族，有PRA和PRB两种亚型，在调节和控制卵巢，子宫和乳腺的功能方面有重要作用。研究表明，在雌激素受体阳性（ER+）的乳腺癌病人中，PR的表达与否不会对病人接受他莫西芬治疗的疗效产生影响。但是在雌激素受体表达阴性（ER-）的乳腺癌病人中，病人接受他莫西芬治疗的疗效依赖于PR的表达。因此，监测PR的表达对乳腺癌的早期诊断和ER-/PR+病人的治疗都是很重要的。PET的灵敏度高，空间分辨率好，安全性也较好 ...
吴晓伟
core
Methods in Ecology and Evolution, Volume 15, Issue 8, Page 1408-1421, August 2024.Abstract Environmental DNA (eDNA) monitoring of species distribution has become a critical tool in ecology, conservation biology and fisheries for identifying the presence and distribution of diverse organisms, including important, threatened and invasive species.
Jiwei Yang +4 more
wiley +1 more source